node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C51E3.6 | R09H10.3 | C51E3.6.1 | R09H10.3a.1 | Uncharacterized protein. | Probable 5-hydroxyisourate hydrolase R09H10.3; Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | 0.468 |
C51E3.6 | ZK697.8 | C51E3.6.1 | ZK697.8.1 | Uncharacterized protein. | Probable 5-hydroxyisourate hydrolase ZK697.8; Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | 0.452 |
R09H10.3 | C51E3.6 | R09H10.3a.1 | C51E3.6.1 | Probable 5-hydroxyisourate hydrolase R09H10.3; Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | Uncharacterized protein. | 0.468 |
R09H10.3 | T09F3.2 | R09H10.3a.1 | T09F3.2.1 | Probable 5-hydroxyisourate hydrolase R09H10.3; Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | Carrier protein (C2); Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.742 |
R09H10.3 | ZK697.8 | R09H10.3a.1 | ZK697.8.1 | Probable 5-hydroxyisourate hydrolase R09H10.3; Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | Probable 5-hydroxyisourate hydrolase ZK697.8; Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | 0.901 |
R09H10.3 | kmo-1 | R09H10.3a.1 | R07B7.5.1 | Probable 5-hydroxyisourate hydrolase R09H10.3; Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | 0.511 |
R09H10.3 | kmo-2 | R09H10.3a.1 | R07B7.4b.1 | Probable 5-hydroxyisourate hydrolase R09H10.3; Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | FAD_binding_3 domain-containing protein. | 0.495 |
R09H10.3 | lad-2 | R09H10.3a.1 | Y54G2A.25a.1 | Probable 5-hydroxyisourate hydrolase R09H10.3; Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | Immunoglobulin domain-containing protein Y54G2A.25. | 0.500 |
R09H10.3 | lpr-2 | R09H10.3a.1 | T12A7.5.1 | Probable 5-hydroxyisourate hydrolase R09H10.3; Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | LiPocalin-Related protein. | 0.700 |
R09H10.3 | pqn-53 | R09H10.3a.1 | R07B7.3a.1 | Probable 5-hydroxyisourate hydrolase R09H10.3; Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | Prion-like-(Q/N-rich)-domain-bearing protein. | 0.495 |
R09H10.3 | suox-1 | R09H10.3a.1 | H13N06.4a.1 | Probable 5-hydroxyisourate hydrolase R09H10.3; Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | Cytochrome b5 heme-binding domain-containing protein. | 0.514 |
R09H10.3 | ttn-1 | R09H10.3a.1 | W06H8.8f.1 | Probable 5-hydroxyisourate hydrolase R09H10.3; Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | Titin homolog; Serine/threonine-protein kinase. Key component in the assembly and functioning of muscles. By providing connections at the level of individual microfilaments, it contributes to the fine balance of forces between the two halves of the sarcomere. The size and extensibility of the cross-links are the main determinants of sarcomere extensibility properties of muscle. In non-muscle cells, seems to play a role in chromosome condensation and chromosome segregation during mitosis. Might link the lamina network to chromatin or nuclear actin, or both during interphase (By similarity). | 0.499 |
T09F3.2 | R09H10.3 | T09F3.2.1 | R09H10.3a.1 | Carrier protein (C2); Belongs to the mitochondrial carrier (TC 2.A.29) family. | Probable 5-hydroxyisourate hydrolase R09H10.3; Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | 0.742 |
T09F3.2 | ZK697.8 | T09F3.2.1 | ZK697.8.1 | Carrier protein (C2); Belongs to the mitochondrial carrier (TC 2.A.29) family. | Probable 5-hydroxyisourate hydrolase ZK697.8; Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | 0.742 |
ZK697.8 | C51E3.6 | ZK697.8.1 | C51E3.6.1 | Probable 5-hydroxyisourate hydrolase ZK697.8; Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | Uncharacterized protein. | 0.452 |
ZK697.8 | R09H10.3 | ZK697.8.1 | R09H10.3a.1 | Probable 5-hydroxyisourate hydrolase ZK697.8; Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | Probable 5-hydroxyisourate hydrolase R09H10.3; Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | 0.901 |
ZK697.8 | T09F3.2 | ZK697.8.1 | T09F3.2.1 | Probable 5-hydroxyisourate hydrolase ZK697.8; Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | Carrier protein (C2); Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.742 |
ZK697.8 | kmo-1 | ZK697.8.1 | R07B7.5.1 | Probable 5-hydroxyisourate hydrolase ZK697.8; Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | 0.495 |
ZK697.8 | kmo-2 | ZK697.8.1 | R07B7.4b.1 | Probable 5-hydroxyisourate hydrolase ZK697.8; Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | FAD_binding_3 domain-containing protein. | 0.495 |
ZK697.8 | lad-2 | ZK697.8.1 | Y54G2A.25a.1 | Probable 5-hydroxyisourate hydrolase ZK697.8; Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | Immunoglobulin domain-containing protein Y54G2A.25. | 0.500 |