STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gkow-1G-patch domain and KOW motifs-containing protein homolog 1; Belongs to the MOS2 family. (462 aa)    
Predicted Functional Partners:
mog-4
Probable pre-mRNA-splicing factor ATP-dependent RNA helicase mog-4; ATP-binding RNA helicase involved in pre-mRNA splicing (Probable). Operates during embryogenesis.
   
 
 0.981
mog-1
Probable pre-mRNA-splicing factor ATP-dependent RNA helicase mog-1; Probable ATP-binding RNA helicase involved in pre-mRNA splicing; Belongs to the DEAD box helicase family. DEAH subfamily. PRP16 sub-subfamily.
   
 
 0.958
R08D7.1
BUD13 homolog; Belongs to the CWC26 family.
   
 
 0.945
stip-1
Septin and tuftelin-interacting protein 1 homolog; May be involved in pre-mRNA splicing (By similarity). Required for embryonic development and survival.
   
  
 0.917
mrpl-54
Mitochondrial Ribosomal Protein, Large.
   
  
 0.894
prp-8
Pre-mRNA-splicing factor 8 homolog; Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex. Functions as scaffold that positions spliceosomal U2, U5 and U6 snRNAs at splice sites on pre-mRNA substrates, so that splicing can occur. Interacts with both the 5' and the 3' splice site.
    
 
 0.878
teg-4
CPSF_A domain-containing protein.
   
   0.851
rpl-24.2
Probable ribosome biogenesis protein RLP24; Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of NOG1 to pre-60S particles (By similarity).
      
 0.807
rbm-5
RNA Binding Motif protein homolog.
   
 
 0.802
rsr-1
PWI domain-containing protein.
    
   0.749
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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