STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ten-1Teneurin-1; Plays a role in the gonadal basement membrane maintenance and/or adhesion early in development. Contributes to the guidance of pharyngeal neurons. (2837 aa)    
Predicted Functional Partners:
lat-1
Latrophilin-like protein 1; Has a role in the establishment of anterior-posterior polarity in tissues during embryogenesis. Required for the alignment of the mitotic spindles and division planes. May have a role in cell death events. Required for normal defection and oocyte fertilization. Involved in sperm function. Operates in pharyngeal pumping during feeding. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
   
 
 0.996
cdap-2
CD2AP homolog.
   
    0.846
eva-1
Protein eva-1; Acts as a receptor for slt-1. Required for the guidance of the AVM pioneer axon to the ventral nerve cord. Acts as a unc-40 coreceptor to enhance the sensitivity of unc-40 to the madd-4 midline guidance cue to guide muscle arm extensions (muscle arms) and AVM mechanosensory axons towards the dorsoventral midline. Belongs to the EVA1 family.
   
 
 0.840
R10D12.15
Uncharacterized protein.
   
   0.818
lin-66
Uncharacterized protein.
   
    0.796
ina-1
Integrin alpha ina-1; Plays a role in cell migration, axon fasciculation, and morphogenesis. During gonad morphogenesis, involved in distal tip cells (DTC)-mediated guidance of gonad elongation, in maintaining their sharp tapering morphology and in their migration. Involved in the anterior-posterior positioning of QR neuroblast descendants by regulating the migratory speed of QR.p. Probably by acting as a receptor for apoptotic cells, plays a role in the clearance of apoptotic cells during mid-embryogenesis. Belongs to the integrin alpha chain family.
   
 
 0.793
dgn-1
Peptidase S72 domain-containing protein.
   
  
 0.783
C08B6.4
Uncharacterized protein.
    
   0.719
T05H4.7
Uncharacterized protein.
    
   0.719
T26F2.1
Uncharacterized protein.
    
   0.719
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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