STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mbk-1Dual specificity tyrosine-phosphorylation-regulated kinase mbk-1; Possible role in the function of olfactory neurons. Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily. (882 aa)    
Predicted Functional Partners:
swan-1
WD_REPEATS_REGION domain-containing protein.
   
 
 0.946
swan-2
WD_REPEATS_REGION domain-containing protein.
   
 
 0.941
K02C4.3
Probable ubiquitin carboxyl-terminal hydrolase K02C4.3.
   
 
 0.731
cysl-2
Bifunctional L-3-cyanoalanine synthase/cysteine synthase; Primarily catalyzes the formation of cyanoalanine and hydrogen sulfide from cysteine and hydrogen cyanide. Can also catalyze, although less efficiently, the formation of cyanoalanine and hydrogen sulfide from either S-sulfocysteine or O-acetylserine and hydrogen cyanide and the formation of cysteine from either S-sulfocysteine or O- acetylserine and hydrogen sulfide. By catalyzing the assimilation of cyanide produced by P.aeruginosa, mediates resistance to infection. Involved in fertility, growth and aging. Does not mediate surv [...]
      
 0.660
Y105E8A.1
Glutaredoxin domain-containing protein.
   
  
 0.620
cysl-4
Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
      
 0.618
set-29
SET domain-containing protein.
      
 0.617
D1037.1
Uncharacterized protein.
   
 
 0.596
dnsn-1
Downstream Neighbor of SoN homolog.
      
 0.588
B0024.15
Hexosyltransferase.
      
 0.586
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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