STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sdz-30SKN-1 Dependent Zygotic transcript. (544 aa)    
Predicted Functional Partners:
C35E7.6
Uncharacterized protein.
      
 0.800
epg-2
Ectopic P granules protein 2; Involved in autophagy. Thought to act as an adapter protein that brings PGL granules to autophagic structures containing lgg-1. Association with other adapters such as sepa-1 is required for the accumulation and degradation of germ cell specific P-granules by autophagy in somatic cells. This ensures exclusive localization of the P-granules in germ cells. May also play a role in the removal of sepa-1 from somatic cells.
   
 
 0.757
sepa-1
Protein sepa-1; Adapter protein that connects P-granules in somatic cells with the autophagic machinery. Association with other adapters such as epg-2 and P-granule components such as pgl-3 is required for the accumulation and degradation of P-granules by autophagy in somatic cells. This ensures exclusive localization of the P-granules in germ cells.
   
 
0.679
sdz-9
SKN-1 Dependent Zygotic transcript.
   
    0.677
vet-6
Very Early Transcript.
   
  
0.640
sqst-1
SeQueSTosome related.
    
 
 0.640
Y106G6D.2
Uncharacterized protein.
   
    0.629
skr-9
SKp1 Related (Ubiquitin ligase complex component); Belongs to the SKP1 family.
   
   0.628
skr-8
SKp1 Related (Ubiquitin ligase complex component); Belongs to the SKP1 family.
   
   0.628
fbxb-22
FBA_2 domain-containing protein.
   
   0.605
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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