node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C14F11.4 | ttr-14 | C14F11.4a.1 | T05A10.3.1 | Uncharacterized protein. | TransThyretin-Related family domain. | 0.846 |
apa-2 | aps-2 | T20B5.1.1 | F02E8.3.1 | AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. | 0.999 |
apa-2 | chc-1 | T20B5.1.1 | T20G5.1.1 | AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. | Probable clathrin heavy chain 1; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles (By similarity). May play a role in yolk protein clatherin-mediated endocytosis by oocytes during oogenesis ; Belongs to the clathrin heavy chain family. | 0.966 |
apa-2 | clic-1 | T20B5.1.1 | T05B11.3.1 | AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. | Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. | 0.903 |
apa-2 | dpy-23 | T20B5.1.1 | R160.1a.1 | AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. | AP-2 complex subunit mu; Component of the adaptor complexes which link clathrin to receptors in coated vesicles (By similarity). Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (By similarity). AP50 is a subunit of the plasma membrane adaptor (By similarity). Essential wnt/egl-20 signaling protein that functions in wnt/egl-20-producing cells. Required for the AP-2 complex-mediated endocytosis of membrane proteins including wntless homolog mig-14 in egl-20-producing cells. During [...] | 0.999 |
apa-2 | epn-1 | T20B5.1.1 | T04C10.2b.1 | AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. | ENTH domain-containing protein. | 0.930 |
apa-2 | ttr-14 | T20B5.1.1 | T05A10.3.1 | AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. | TransThyretin-Related family domain. | 0.790 |
apa-2 | unc-11 | T20B5.1.1 | C32E8.10c.1 | AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. | Phosphatidylinositol-binding clathrin assembly protein unc-11; Assembly protein recruiting clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. May be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. Involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. Required for the efficient targeting of the synaptic vesicle protein synaptobrevin. Belongs to the PICALM/SNAP91 family. | 0.914 |
apa-2 | unc-41 | T20B5.1.1 | C27H6.1a.1 | AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. | Putative stoned B-like protein; Potential adapter protein, which may be involved in endocytic vesicle recycling of synaptic vesicles; Belongs to the Stoned B family. | 0.827 |
aps-2 | apa-2 | F02E8.3.1 | T20B5.1.1 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. | AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. | 0.999 |
aps-2 | chc-1 | F02E8.3.1 | T20G5.1.1 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. | Probable clathrin heavy chain 1; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles (By similarity). May play a role in yolk protein clatherin-mediated endocytosis by oocytes during oogenesis ; Belongs to the clathrin heavy chain family. | 0.860 |
aps-2 | clic-1 | F02E8.3.1 | T05B11.3.1 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. | Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. | 0.788 |
aps-2 | dpy-23 | F02E8.3.1 | R160.1a.1 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. | AP-2 complex subunit mu; Component of the adaptor complexes which link clathrin to receptors in coated vesicles (By similarity). Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (By similarity). AP50 is a subunit of the plasma membrane adaptor (By similarity). Essential wnt/egl-20 signaling protein that functions in wnt/egl-20-producing cells. Required for the AP-2 complex-mediated endocytosis of membrane proteins including wntless homolog mig-14 in egl-20-producing cells. During [...] | 0.999 |
aps-2 | epn-1 | F02E8.3.1 | T04C10.2b.1 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. | ENTH domain-containing protein. | 0.563 |
aps-2 | ttr-14 | F02E8.3.1 | T05A10.3.1 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. | TransThyretin-Related family domain. | 0.645 |
aps-2 | unc-11 | F02E8.3.1 | C32E8.10c.1 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. | Phosphatidylinositol-binding clathrin assembly protein unc-11; Assembly protein recruiting clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. May be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. Involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. Required for the efficient targeting of the synaptic vesicle protein synaptobrevin. Belongs to the PICALM/SNAP91 family. | 0.568 |
aps-2 | unc-41 | F02E8.3.1 | C27H6.1a.1 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. | Putative stoned B-like protein; Potential adapter protein, which may be involved in endocytic vesicle recycling of synaptic vesicles; Belongs to the Stoned B family. | 0.771 |
chc-1 | apa-2 | T20G5.1.1 | T20B5.1.1 | Probable clathrin heavy chain 1; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles (By similarity). May play a role in yolk protein clatherin-mediated endocytosis by oocytes during oogenesis ; Belongs to the clathrin heavy chain family. | AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. | 0.966 |
chc-1 | aps-2 | T20G5.1.1 | F02E8.3.1 | Probable clathrin heavy chain 1; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles (By similarity). May play a role in yolk protein clatherin-mediated endocytosis by oocytes during oogenesis ; Belongs to the clathrin heavy chain family. | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. | 0.860 |
chc-1 | clic-1 | T20G5.1.1 | T05B11.3.1 | Probable clathrin heavy chain 1; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles (By similarity). May play a role in yolk protein clatherin-mediated endocytosis by oocytes during oogenesis ; Belongs to the clathrin heavy chain family. | Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. | 0.999 |