node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
exo-1 | him-14 | F45G2.3.1 | ZK1127.11.1 | EXOnuclease. | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | 0.967 |
exo-1 | msh-5 | F45G2.3.1 | F09E8.3a.1 | EXOnuclease. | MutS protein homolog 5; Crucial component in meiotic recombination, functioning at some point after the initiation step of recombination. Plays a role in promoting the crossover outcome of meiotic recombination events. Required for formation of normal meiotic crossover, and crossover and chiasmata generated by artificially made DNA breaks. | 0.822 |
exo-1 | mus-81 | F45G2.3.1 | C43E11.2a.1 | EXOnuclease. | ERCC4 domain-containing protein. | 0.986 |
exo-1 | rad-51 | F45G2.3.1 | Y43C5A.6a.1 | EXOnuclease. | DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. | 0.991 |
exo-1 | rad-54 | F45G2.3.1 | W06D4.6.1 | EXOnuclease. | Uncharacterized protein. | 0.943 |
exo-1 | smc-3 | F45G2.3.1 | Y47D3A.26b.1 | EXOnuclease. | Structural maintenance of chromosomes protein 3; Involved in chromosome cohesion during cell cycle and in DNA repair. Involved in the repair of double strand breaks during mitosis and meiosis. Required for chromosome segregation during mitosis. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped (By similarity). At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chrom [...] | 0.708 |
exo-1 | spo-11 | F45G2.3.1 | T05E11.4a.1 | EXOnuclease. | Meiotic recombination protein spo-11; Required for meiotic recombination. Mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. | 0.972 |
exo-1 | zhp-3 | F45G2.3.1 | K02B12.8b.1 | EXOnuclease. | RING-type domain-containing protein. | 0.437 |
him-14 | exo-1 | ZK1127.11.1 | F45G2.3.1 | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | EXOnuclease. | 0.967 |
him-14 | htp-3 | ZK1127.11.1 | F57C9.5.1 | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | HORMA domain-containing protein. | 0.744 |
him-14 | msh-5 | ZK1127.11.1 | F09E8.3a.1 | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | MutS protein homolog 5; Crucial component in meiotic recombination, functioning at some point after the initiation step of recombination. Plays a role in promoting the crossover outcome of meiotic recombination events. Required for formation of normal meiotic crossover, and crossover and chiasmata generated by artificially made DNA breaks. | 0.999 |
him-14 | mus-81 | ZK1127.11.1 | C43E11.2a.1 | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | ERCC4 domain-containing protein. | 0.979 |
him-14 | rad-51 | ZK1127.11.1 | Y43C5A.6a.1 | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. | 0.935 |
him-14 | rad-54 | ZK1127.11.1 | W06D4.6.1 | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | Uncharacterized protein. | 0.808 |
him-14 | smc-3 | ZK1127.11.1 | Y47D3A.26b.1 | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | Structural maintenance of chromosomes protein 3; Involved in chromosome cohesion during cell cycle and in DNA repair. Involved in the repair of double strand breaks during mitosis and meiosis. Required for chromosome segregation during mitosis. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped (By similarity). At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chrom [...] | 0.825 |
him-14 | spo-11 | ZK1127.11.1 | T05E11.4a.1 | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | Meiotic recombination protein spo-11; Required for meiotic recombination. Mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. | 0.991 |
him-14 | syp-2 | ZK1127.11.1 | C24G6.1.1 | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | Uncharacterized protein. | 0.844 |
him-14 | zhp-3 | ZK1127.11.1 | K02B12.8b.1 | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | RING-type domain-containing protein. | 0.922 |
htp-3 | him-14 | F57C9.5.1 | ZK1127.11.1 | HORMA domain-containing protein. | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | 0.744 |
htp-3 | msh-5 | F57C9.5.1 | F09E8.3a.1 | HORMA domain-containing protein. | MutS protein homolog 5; Crucial component in meiotic recombination, functioning at some point after the initiation step of recombination. Plays a role in promoting the crossover outcome of meiotic recombination events. Required for formation of normal meiotic crossover, and crossover and chiasmata generated by artificially made DNA breaks. | 0.854 |