node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
dhps-1 | iff-1 | Y17G7B.4.1 | T05G5.10a.1 | Deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a critical lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. This is the first step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine. Hypusination is unique to mature eIF-5A factor and is essential for its function. | Eukaryotic translation initiation factor 5A-1; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis (By similarity). Required for mitotic germ cell proliferation, gametogenesis after entry into meiosis, and localization of the P granule component pgl-1 on P granules; Belongs to the eIF-5A family. | 0.987 |
iff-1 | dhps-1 | T05G5.10a.1 | Y17G7B.4.1 | Eukaryotic translation initiation factor 5A-1; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis (By similarity). Required for mitotic germ cell proliferation, gametogenesis after entry into meiosis, and localization of the P granule component pgl-1 on P granules; Belongs to the eIF-5A family. | Deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a critical lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. This is the first step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine. Hypusination is unique to mature eIF-5A factor and is essential for its function. | 0.987 |
iff-1 | rpl-23 | T05G5.10a.1 | B0336.10.3 | Eukaryotic translation initiation factor 5A-1; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis (By similarity). Required for mitotic germ cell proliferation, gametogenesis after entry into meiosis, and localization of the P granule component pgl-1 on P granules; Belongs to the eIF-5A family. | 60S ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family. | 0.988 |
iff-1 | rpl-35 | T05G5.10a.1 | ZK652.4.3 | Eukaryotic translation initiation factor 5A-1; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis (By similarity). Required for mitotic germ cell proliferation, gametogenesis after entry into meiosis, and localization of the P granule component pgl-1 on P granules; Belongs to the eIF-5A family. | 60S ribosomal protein L35; Belongs to the universal ribosomal protein uL29 family. | 0.986 |
iff-1 | rpl-5 | T05G5.10a.1 | F54C9.5.1 | Eukaryotic translation initiation factor 5A-1; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis (By similarity). Required for mitotic germ cell proliferation, gametogenesis after entry into meiosis, and localization of the P granule component pgl-1 on P granules; Belongs to the eIF-5A family. | 60S ribosomal protein L5; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] | 0.989 |
iff-1 | rps-1 | T05G5.10a.1 | F56F3.5.2 | Eukaryotic translation initiation factor 5A-1; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis (By similarity). Required for mitotic germ cell proliferation, gametogenesis after entry into meiosis, and localization of the P granule component pgl-1 on P granules; Belongs to the eIF-5A family. | 40S ribosomal protein S3a; Belongs to the eukaryotic ribosomal protein eS1 family. | 0.985 |
iff-1 | rps-11 | T05G5.10a.1 | F40F11.1.1 | Eukaryotic translation initiation factor 5A-1; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis (By similarity). Required for mitotic germ cell proliferation, gametogenesis after entry into meiosis, and localization of the P granule component pgl-1 on P granules; Belongs to the eIF-5A family. | Ribosomal_S17_N domain-containing protein; Belongs to the universal ribosomal protein uS17 family. | 0.988 |
iff-1 | rps-15 | T05G5.10a.1 | F36A2.6.1 | Eukaryotic translation initiation factor 5A-1; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis (By similarity). Required for mitotic germ cell proliferation, gametogenesis after entry into meiosis, and localization of the P granule component pgl-1 on P granules; Belongs to the eIF-5A family. | 40S ribosomal protein S15; Negatively regulates lifespan. | 0.989 |
iff-1 | rps-18 | T05G5.10a.1 | Y57G11C.16.1 | Eukaryotic translation initiation factor 5A-1; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis (By similarity). Required for mitotic germ cell proliferation, gametogenesis after entry into meiosis, and localization of the P granule component pgl-1 on P granules; Belongs to the eIF-5A family. | Ribosomal Protein, Small subunit; Belongs to the universal ribosomal protein uS13 family. | 0.988 |
iff-1 | rps-3 | T05G5.10a.1 | C23G10.3.1 | Eukaryotic translation initiation factor 5A-1; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis (By similarity). Required for mitotic germ cell proliferation, gametogenesis after entry into meiosis, and localization of the P granule component pgl-1 on P granules; Belongs to the eIF-5A family. | 40S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. | 0.987 |
iff-1 | rps-30 | T05G5.10a.1 | C26F1.4.3 | Eukaryotic translation initiation factor 5A-1; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis (By similarity). Required for mitotic germ cell proliferation, gametogenesis after entry into meiosis, and localization of the P granule component pgl-1 on P granules; Belongs to the eIF-5A family. | 40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. | 0.994 |
rpl-23 | iff-1 | B0336.10.3 | T05G5.10a.1 | 60S ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family. | Eukaryotic translation initiation factor 5A-1; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis (By similarity). Required for mitotic germ cell proliferation, gametogenesis after entry into meiosis, and localization of the P granule component pgl-1 on P granules; Belongs to the eIF-5A family. | 0.988 |
rpl-23 | rpl-35 | B0336.10.3 | ZK652.4.3 | 60S ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family. | 60S ribosomal protein L35; Belongs to the universal ribosomal protein uL29 family. | 0.999 |
rpl-23 | rpl-5 | B0336.10.3 | F54C9.5.1 | 60S ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family. | 60S ribosomal protein L5; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] | 0.999 |
rpl-23 | rps-1 | B0336.10.3 | F56F3.5.2 | 60S ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family. | 40S ribosomal protein S3a; Belongs to the eukaryotic ribosomal protein eS1 family. | 0.999 |
rpl-23 | rps-11 | B0336.10.3 | F40F11.1.1 | 60S ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family. | Ribosomal_S17_N domain-containing protein; Belongs to the universal ribosomal protein uS17 family. | 0.999 |
rpl-23 | rps-15 | B0336.10.3 | F36A2.6.1 | 60S ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family. | 40S ribosomal protein S15; Negatively regulates lifespan. | 0.999 |
rpl-23 | rps-18 | B0336.10.3 | Y57G11C.16.1 | 60S ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family. | Ribosomal Protein, Small subunit; Belongs to the universal ribosomal protein uS13 family. | 0.999 |
rpl-23 | rps-3 | B0336.10.3 | C23G10.3.1 | 60S ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family. | 40S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. | 0.999 |
rpl-23 | rps-30 | B0336.10.3 | C26F1.4.3 | 60S ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family. | 40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. | 0.999 |