node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
W03G9.8 | gip-1 | W03G9.8.1 | H04J21.3b.1 | Mitotic spindle organiZing protein (MOZART) homolog. | Gamma-tubulin complex component. | 0.929 |
W03G9.8 | gip-2 | W03G9.8.1 | C45G3.5.1 | Mitotic spindle organiZing protein (MOZART) homolog. | Gamma-tubulin interacting protein 2; Recruited to hemidesomosomes in early embryonic elongation to direct the nucleation and growth of non-centrosomal microtubules. | 0.938 |
W03G9.8 | noca-1 | W03G9.8.1 | T09E8.1h.1 | Mitotic spindle organiZing protein (MOZART) homolog. | Non-centrosomal microtubule array protein 1; Plays a role in the assembly of microtubule arrays in the germline acting redundantly with ptrn-1 to control circumferential microtubule assembly along the body which is necessary for larval development, viability, and morphology and integrity of the epidermis. Required for microtubule stability and anchorage by binding to microtubule minus ends. Recruited to hemidesomosomes in early embryonic elongation to direct the nucleation and growth of non-centrosomal microtubules. [Isoform h]: Directs the assembly of non-centrosomal microtubule array [...] | 0.690 |
W03G9.8 | ptrn-1 | W03G9.8.1 | F35B3.5c.1 | Mitotic spindle organiZing protein (MOZART) homolog. | Patronin (microtubule-binding protein) homolog; Required for microtubule stability and anchorage by binding to the minus ends of microtubules. Acts redundantly with noca-1 to control circumferential microtubule assembly along the body which is necessary for larval development, viability, morphology and integrity of the epidermis. Promotes microtubule stability and polymerization in neurons. Involved in the maintenance of neurite morphology in ALM and PLM neurons. May play a role in synaptic protein localization in the PLM neuron. May act upstream of dlk-1 in neuronal regeneration. Play [...] | 0.459 |
W03G9.8 | tbg-1 | W03G9.8.1 | F58A4.8.1 | Mitotic spindle organiZing protein (MOZART) homolog. | Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly. | 0.880 |
W03G9.8 | zyg-9 | W03G9.8.1 | F22B5.7.1 | Mitotic spindle organiZing protein (MOZART) homolog. | Zygote defective protein 9; Plays a major role in organizing microtubules and spindle poles during mitosis and meiosis in one-cell stage embryos. Required for default nucleus positioning in oocytes. | 0.669 |
gip-1 | W03G9.8 | H04J21.3b.1 | W03G9.8.1 | Gamma-tubulin complex component. | Mitotic spindle organiZing protein (MOZART) homolog. | 0.929 |
gip-1 | gip-2 | H04J21.3b.1 | C45G3.5.1 | Gamma-tubulin complex component. | Gamma-tubulin interacting protein 2; Recruited to hemidesomosomes in early embryonic elongation to direct the nucleation and growth of non-centrosomal microtubules. | 0.950 |
gip-1 | noca-1 | H04J21.3b.1 | T09E8.1h.1 | Gamma-tubulin complex component. | Non-centrosomal microtubule array protein 1; Plays a role in the assembly of microtubule arrays in the germline acting redundantly with ptrn-1 to control circumferential microtubule assembly along the body which is necessary for larval development, viability, and morphology and integrity of the epidermis. Required for microtubule stability and anchorage by binding to microtubule minus ends. Recruited to hemidesomosomes in early embryonic elongation to direct the nucleation and growth of non-centrosomal microtubules. [Isoform h]: Directs the assembly of non-centrosomal microtubule array [...] | 0.855 |
gip-1 | ptrn-1 | H04J21.3b.1 | F35B3.5c.1 | Gamma-tubulin complex component. | Patronin (microtubule-binding protein) homolog; Required for microtubule stability and anchorage by binding to the minus ends of microtubules. Acts redundantly with noca-1 to control circumferential microtubule assembly along the body which is necessary for larval development, viability, morphology and integrity of the epidermis. Promotes microtubule stability and polymerization in neurons. Involved in the maintenance of neurite morphology in ALM and PLM neurons. May play a role in synaptic protein localization in the PLM neuron. May act upstream of dlk-1 in neuronal regeneration. Play [...] | 0.827 |
gip-1 | tbg-1 | H04J21.3b.1 | F58A4.8.1 | Gamma-tubulin complex component. | Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly. | 0.999 |
gip-1 | zyg-9 | H04J21.3b.1 | F22B5.7.1 | Gamma-tubulin complex component. | Zygote defective protein 9; Plays a major role in organizing microtubules and spindle poles during mitosis and meiosis in one-cell stage embryos. Required for default nucleus positioning in oocytes. | 0.827 |
gip-2 | W03G9.8 | C45G3.5.1 | W03G9.8.1 | Gamma-tubulin interacting protein 2; Recruited to hemidesomosomes in early embryonic elongation to direct the nucleation and growth of non-centrosomal microtubules. | Mitotic spindle organiZing protein (MOZART) homolog. | 0.938 |
gip-2 | gip-1 | C45G3.5.1 | H04J21.3b.1 | Gamma-tubulin interacting protein 2; Recruited to hemidesomosomes in early embryonic elongation to direct the nucleation and growth of non-centrosomal microtubules. | Gamma-tubulin complex component. | 0.950 |
gip-2 | noca-1 | C45G3.5.1 | T09E8.1h.1 | Gamma-tubulin interacting protein 2; Recruited to hemidesomosomes in early embryonic elongation to direct the nucleation and growth of non-centrosomal microtubules. | Non-centrosomal microtubule array protein 1; Plays a role in the assembly of microtubule arrays in the germline acting redundantly with ptrn-1 to control circumferential microtubule assembly along the body which is necessary for larval development, viability, and morphology and integrity of the epidermis. Required for microtubule stability and anchorage by binding to microtubule minus ends. Recruited to hemidesomosomes in early embryonic elongation to direct the nucleation and growth of non-centrosomal microtubules. [Isoform h]: Directs the assembly of non-centrosomal microtubule array [...] | 0.811 |
gip-2 | ptrn-1 | C45G3.5.1 | F35B3.5c.1 | Gamma-tubulin interacting protein 2; Recruited to hemidesomosomes in early embryonic elongation to direct the nucleation and growth of non-centrosomal microtubules. | Patronin (microtubule-binding protein) homolog; Required for microtubule stability and anchorage by binding to the minus ends of microtubules. Acts redundantly with noca-1 to control circumferential microtubule assembly along the body which is necessary for larval development, viability, morphology and integrity of the epidermis. Promotes microtubule stability and polymerization in neurons. Involved in the maintenance of neurite morphology in ALM and PLM neurons. May play a role in synaptic protein localization in the PLM neuron. May act upstream of dlk-1 in neuronal regeneration. Play [...] | 0.662 |
gip-2 | tbg-1 | C45G3.5.1 | F58A4.8.1 | Gamma-tubulin interacting protein 2; Recruited to hemidesomosomes in early embryonic elongation to direct the nucleation and growth of non-centrosomal microtubules. | Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly. | 0.912 |
htz-1 | noca-1 | R08C7.3.3 | T09E8.1h.1 | Histone H2A.V; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). Required to maintain non-distal tip cell (DTC) fate of somatic gonadal [...] | Non-centrosomal microtubule array protein 1; Plays a role in the assembly of microtubule arrays in the germline acting redundantly with ptrn-1 to control circumferential microtubule assembly along the body which is necessary for larval development, viability, and morphology and integrity of the epidermis. Required for microtubule stability and anchorage by binding to microtubule minus ends. Recruited to hemidesomosomes in early embryonic elongation to direct the nucleation and growth of non-centrosomal microtubules. [Isoform h]: Directs the assembly of non-centrosomal microtubule array [...] | 0.602 |
maph-1.1 | noca-1 | F32A7.5a.1 | T09E8.1h.1 | Microtubule-associated protein homolog maph-1.1; Belongs to the MAP1A/MAP1B/MAP1S family. | Non-centrosomal microtubule array protein 1; Plays a role in the assembly of microtubule arrays in the germline acting redundantly with ptrn-1 to control circumferential microtubule assembly along the body which is necessary for larval development, viability, and morphology and integrity of the epidermis. Required for microtubule stability and anchorage by binding to microtubule minus ends. Recruited to hemidesomosomes in early embryonic elongation to direct the nucleation and growth of non-centrosomal microtubules. [Isoform h]: Directs the assembly of non-centrosomal microtubule array [...] | 0.585 |
noca-1 | W03G9.8 | T09E8.1h.1 | W03G9.8.1 | Non-centrosomal microtubule array protein 1; Plays a role in the assembly of microtubule arrays in the germline acting redundantly with ptrn-1 to control circumferential microtubule assembly along the body which is necessary for larval development, viability, and morphology and integrity of the epidermis. Required for microtubule stability and anchorage by binding to microtubule minus ends. Recruited to hemidesomosomes in early embryonic elongation to direct the nucleation and growth of non-centrosomal microtubules. [Isoform h]: Directs the assembly of non-centrosomal microtubule array [...] | Mitotic spindle organiZing protein (MOZART) homolog. | 0.690 |