node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
rab-3 | ric-4 | C18A3.6a.1 | Y22F5A.3b.1 | Ras-related protein Rab-3; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal (By similarity). Plays a role in the recruitment of endophilin unc-57 to synaptic vesicles. Probably by controlling dense-core vesicle trafficking, plays a role in the AVG neuron-mediated formation of the right axon tract of the ventral nerve cord. Belongs to the small GTPase superfamily. Rab family. | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | 0.888 |
rab-3 | snb-1 | C18A3.6a.1 | T10H9.4.1 | Ras-related protein Rab-3; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal (By similarity). Plays a role in the recruitment of endophilin unc-57 to synaptic vesicles. Probably by controlling dense-core vesicle trafficking, plays a role in the AVG neuron-mediated formation of the right axon tract of the ventral nerve cord. Belongs to the small GTPase superfamily. Rab family. | Synaptobrevin-1; Involved in the targeting and/or fusion of transport vesicles to their target membrane. Acts in neuronal exocytosis of synaptic transmission. Likely to have a role in cholinergic transmisson. Required for viability, coordinated movement and M3 pharynx motor neuron function. | 0.942 |
rab-3 | snt-1 | C18A3.6a.1 | F31E8.2b.1 | Ras-related protein Rab-3; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal (By similarity). Plays a role in the recruitment of endophilin unc-57 to synaptic vesicles. Probably by controlling dense-core vesicle trafficking, plays a role in the AVG neuron-mediated formation of the right axon tract of the ventral nerve cord. Belongs to the small GTPase superfamily. Rab family. | Synaptotagmin-1; May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone (By similarity). Involved in necrotic cell death. | 0.975 |
rab-3 | syd-2 | C18A3.6a.1 | F59F5.6.1 | Ras-related protein Rab-3; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal (By similarity). Plays a role in the recruitment of endophilin unc-57 to synaptic vesicles. Probably by controlling dense-core vesicle trafficking, plays a role in the AVG neuron-mediated formation of the right axon tract of the ventral nerve cord. Belongs to the small GTPase superfamily. Rab family. | Liprin-alpha; May play a role in regulating the structure of the neuronal region, called the active zone, from which synaptic vesicles send neurotransmitter signals across the synapse. This may be in association with the liprin-beta protein hlb-1 ; Belongs to the liprin family. Liprin-alpha subfamily. | 0.983 |
rab-3 | unc-18 | C18A3.6a.1 | F27D9.1a.1 | Ras-related protein Rab-3; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal (By similarity). Plays a role in the recruitment of endophilin unc-57 to synaptic vesicles. Probably by controlling dense-core vesicle trafficking, plays a role in the AVG neuron-mediated formation of the right axon tract of the ventral nerve cord. Belongs to the small GTPase superfamily. Rab family. | Putative acetylcholine regulator unc-18; May participate in the axonal transport system and influences the acetylcholine flow in motor neurons. Probably by regulating neuronal transmission downstream of lin-3 and receptor lin-23 and phospholipase plc-3 and upstream of innexin unc-7 and egl-4/PKG in ALA neurons, involved in the decrease in pharyngeal pumping during the quiescent state that precedes each larval molt ; Belongs to the STXBP/unc-18/SEC1 family. | 0.911 |
rab-3 | unc-64 | C18A3.6a.1 | F56A8.7a.2 | Ras-related protein Rab-3; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal (By similarity). Plays a role in the recruitment of endophilin unc-57 to synaptic vesicles. Probably by controlling dense-core vesicle trafficking, plays a role in the AVG neuron-mediated formation of the right axon tract of the ventral nerve cord. Belongs to the small GTPase superfamily. Rab family. | Syntaxin-1A homolog; Plays a critical role in several secretory processes, including cuticle secretion and neurotransmitter release, and probably assists in neuronal membrane maturation or the final stages of neuronal differentiation. Essential for embryonic viability and development. Has a role in dauer formation and adult life span. Required for locomotion. Probably by regulating neuronal transmission downstream of lin-3 and receptor lin-23 and phospholipase plc-3 and upstream of innexin unc-7 and egl-4/PKG in ALA neurons, involved in the decrease in pharyngeal pumping during the qui [...] | 0.869 |
ric-4 | rab-3 | Y22F5A.3b.1 | C18A3.6a.1 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | Ras-related protein Rab-3; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal (By similarity). Plays a role in the recruitment of endophilin unc-57 to synaptic vesicles. Probably by controlling dense-core vesicle trafficking, plays a role in the AVG neuron-mediated formation of the right axon tract of the ventral nerve cord. Belongs to the small GTPase superfamily. Rab family. | 0.888 |
ric-4 | snap-1 | Y22F5A.3b.1 | D1014.3.2 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | SNAP (Soluble NSF Attachment Protein) homolog. | 0.950 |
ric-4 | snb-1 | Y22F5A.3b.1 | T10H9.4.1 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | Synaptobrevin-1; Involved in the targeting and/or fusion of transport vesicles to their target membrane. Acts in neuronal exocytosis of synaptic transmission. Likely to have a role in cholinergic transmisson. Required for viability, coordinated movement and M3 pharynx motor neuron function. | 0.991 |
ric-4 | snt-1 | Y22F5A.3b.1 | F31E8.2b.1 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | Synaptotagmin-1; May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone (By similarity). Involved in necrotic cell death. | 0.986 |
ric-4 | syd-2 | Y22F5A.3b.1 | F59F5.6.1 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | Liprin-alpha; May play a role in regulating the structure of the neuronal region, called the active zone, from which synaptic vesicles send neurotransmitter signals across the synapse. This may be in association with the liprin-beta protein hlb-1 ; Belongs to the liprin family. Liprin-alpha subfamily. | 0.611 |
ric-4 | syx-2 | Y22F5A.3b.1 | F48F7.2.2 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | Putative syntaxin-2; Potentially involved in docking of synaptic vesicles at presynaptic active zones; Belongs to the syntaxin family. | 0.821 |
ric-4 | syx-4 | Y22F5A.3b.1 | T01B11.3.1 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | Putative syntaxin-4; Potentially involved in docking of synaptic vesicles at presynaptic active zones. | 0.787 |
ric-4 | unc-18 | Y22F5A.3b.1 | F27D9.1a.1 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | Putative acetylcholine regulator unc-18; May participate in the axonal transport system and influences the acetylcholine flow in motor neurons. Probably by regulating neuronal transmission downstream of lin-3 and receptor lin-23 and phospholipase plc-3 and upstream of innexin unc-7 and egl-4/PKG in ALA neurons, involved in the decrease in pharyngeal pumping during the quiescent state that precedes each larval molt ; Belongs to the STXBP/unc-18/SEC1 family. | 0.890 |
ric-4 | unc-64 | Y22F5A.3b.1 | F56A8.7a.2 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | Syntaxin-1A homolog; Plays a critical role in several secretory processes, including cuticle secretion and neurotransmitter release, and probably assists in neuronal membrane maturation or the final stages of neuronal differentiation. Essential for embryonic viability and development. Has a role in dauer formation and adult life span. Required for locomotion. Probably by regulating neuronal transmission downstream of lin-3 and receptor lin-23 and phospholipase plc-3 and upstream of innexin unc-7 and egl-4/PKG in ALA neurons, involved in the decrease in pharyngeal pumping during the qui [...] | 0.993 |
ric-4 | vti-1 | Y22F5A.3b.1 | Y57G11C.4.1 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | t-SNARE coiled-coil homology domain-containing protein. | 0.742 |
snap-1 | ric-4 | D1014.3.2 | Y22F5A.3b.1 | SNAP (Soluble NSF Attachment Protein) homolog. | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | 0.950 |
snap-1 | snb-1 | D1014.3.2 | T10H9.4.1 | SNAP (Soluble NSF Attachment Protein) homolog. | Synaptobrevin-1; Involved in the targeting and/or fusion of transport vesicles to their target membrane. Acts in neuronal exocytosis of synaptic transmission. Likely to have a role in cholinergic transmisson. Required for viability, coordinated movement and M3 pharynx motor neuron function. | 0.949 |
snap-1 | snt-1 | D1014.3.2 | F31E8.2b.1 | SNAP (Soluble NSF Attachment Protein) homolog. | Synaptotagmin-1; May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone (By similarity). Involved in necrotic cell death. | 0.440 |
snap-1 | syx-2 | D1014.3.2 | F48F7.2.2 | SNAP (Soluble NSF Attachment Protein) homolog. | Putative syntaxin-2; Potentially involved in docking of synaptic vesicles at presynaptic active zones; Belongs to the syntaxin family. | 0.899 |