STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fat-4Delta(5) fatty acid desaturase fat-4; Catalyzes the desaturation of dihomo-gamma-linoleic acid (DHGLA) (20:3n-6) to generate arachidonic acid (20:4n-6). Also acts on a number of other substrates, including fatty acids that do not contain a double bond at the 8 position; Belongs to the fatty acid desaturase type 1 family. (447 aa)    
Predicted Functional Partners:
fat-1
Omega-3 fatty acid desaturase fat-1; Omega-3 fatty acid desaturase that acts on a range of substrates. Catalyzes the desaturation of linolenic acid (18:2n-6), dihomo-gamma-linoleic acid (DHGLA) (20:3n-6), and arachidonic acid (20:4n-6), to generate gamma linolenic acid (18:3n-3), eicosatetraenoic acid (20:4n-3) and eicosapentaenoic acid (20:5n-3) respectively. Although the enzyme has been suggested to act on glycerolipids, the precise nature of the fatty acid substrate is unknown.
   
 0.941
fat-2
Delta(12) fatty acid desaturase fat-2; Catalyzes the desaturation of oleic acid (Delta(9)-18:1, or C18:1(n-9)) to linoleic acid (Delta(9,12)-18:2, or C18:2(n-6)). This desaturation event is essential for the synthesis of longer chain polyunsaturated fatty acids (PUFAs) such as arachidonic acid (AA, or C20:4(n-6)) and eicosapentaenoic acid (EPA, or C20:5(n-3)).
   
 0.924
fat-6
Delta(9)-fatty-acid desaturase fat-6; Delta(9)-fatty-acid desaturase that acts preferentially on stearoyl-CoA. Also acts on vaccenyl-coA and heptadecanyol-CoA. Belongs to the fatty acid desaturase type 1 family.
  
 
 0.888
Y73F8A.27
2Fe-2S ferredoxin-type domain-containing protein.
  
 
 0.878
elo-1
Elongation of very long chain fatty acids protein.
   
  
 0.844
elo-2
Elongation of very long chain fatty acids protein.
      
 0.833
fat-5
Delta(9)-fatty-acid desaturase fat-5; Delta(9)-fatty-acid desaturase that acts preferentially on palmitoyl-CoA. Also acts on pentadecanoyl-coA and myristoyl-CoA.
  
  
 0.795
fat-7
Delta(9)-fatty-acid desaturase fat-7; Delta(9)-fatty-acid desaturase that acts preferentially on stearoyl-CoA. Also acts on vaccenyl-coA, heptadecanyol-CoA, and palmitoyl-CoA.
  
  
 0.794
pks-1
PolyKetide Synthase.
  
  
 0.724
agmo-1
Alkylglycerol monooxygenase; Glyceryl-ether monooxygenase that cleaves the O-alkyl bond of ether lipids; Belongs to the sterol desaturase family. TMEM195 subfamily.
  
 
 0.708
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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