STRINGSTRING
dnj-21 protein (Caenorhabditis elegans) - STRING interaction network
"dnj-21" - Mitochondrial import inner membrane translocase subunit TIM14 in Caenorhabditis elegans
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnj-21Mitochondrial import inner membrane translocase subunit TIM14; Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity) (112 aa)    
Predicted Functional Partners:
F45G2.8
Mitochondrial import inner membrane translocase subunit tim-16; Regulates ATP-dependent protein translocation into the mitochondrial matrix; Belongs to the TIM16/PAM16 family (136 aa)
     
 
  0.997
scpl-4
Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane (452 aa)
     
 
  0.981
T09B4.9
Probable mitochondrial import inner membrane translocase subunit tin-44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Recruits mitochondrial HSP70 to drive protein translocation into the matrix using ATP as an energy source (425 aa)
     
 
  0.967
E04A4.5
Probable mitochondrial import inner membrane translocase subunit Tim17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane (181 aa)
     
 
  0.962
dnj-15
DNaJ domain (Prokaryotic heat shock protein); Protein DNJ-15 (dnj-15) mRNA, complete cds (211 aa)
     
   
  0.946
F15D3.7
Translocase, Inner Mitochondrial Membrane; Protein F15D3.7 (F15D3.7) mRNA, complete cds (242 aa)
     
 
  0.937
C34C12.8
GrpE protein homolog, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins (By similarity) (237 aa)
   
 
  0.924
F56B3.11
Protein F56B3.11, isoform a (213 aa)
     
 
  0.914
hsp-6
Heat shock 70 kDa protein F, mitochondrial; Protein HSP-6 (hsp-6) mRNA, complete cds; Belongs to the heat shock protein 70 family (657 aa)
   
 
  0.914
F32B6.2
MethylCrotonoyl-Coenzyme A Carboxylase (Alpha); Protein MCCC-1 (21ur-13999) mRNA, complete cds (671 aa)
   
   
  0.914
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Caenorhabditis elegans, Rhabditis elegans, roundworm
Server load: low (16%) [HD]