node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ani-1 | aspm-1 | Y49E10.19.1 | C45G3.1.1 | Anillin-like protein 1; Required for contractile events in embryos that occur prior to mitosis, such as cortical ruffling and pseudocleavage. Promotes membrane ruffling by organizing cortical patches of septins and myosin II. Not generally required for cytokinesis in mitotic cells. Required for the asymmetric cleavage events that extrude the two polar bodies during oocyte meiosis. Not required for meiotic contractile ring assembly, initiation or closure but is required for the transformation of the contractile ring from a disk above the spindle to a tube around the spindle midzone. Pro [...] | Calponin-homology (CH) domain-containing protein. | 0.715 |
ani-1 | bmk-1 | Y49E10.19.1 | F23B12.8b.1 | Anillin-like protein 1; Required for contractile events in embryos that occur prior to mitosis, such as cortical ruffling and pseudocleavage. Promotes membrane ruffling by organizing cortical patches of septins and myosin II. Not generally required for cytokinesis in mitotic cells. Required for the asymmetric cleavage events that extrude the two polar bodies during oocyte meiosis. Not required for meiotic contractile ring assembly, initiation or closure but is required for the transformation of the contractile ring from a disk above the spindle to a tube around the spindle midzone. Pro [...] | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | 0.780 |
ani-1 | cyk-1 | Y49E10.19.1 | F11H8.4b.1 | Anillin-like protein 1; Required for contractile events in embryos that occur prior to mitosis, such as cortical ruffling and pseudocleavage. Promotes membrane ruffling by organizing cortical patches of septins and myosin II. Not generally required for cytokinesis in mitotic cells. Required for the asymmetric cleavage events that extrude the two polar bodies during oocyte meiosis. Not required for meiotic contractile ring assembly, initiation or closure but is required for the transformation of the contractile ring from a disk above the spindle to a tube around the spindle midzone. Pro [...] | CYtoKinesis defect. | 0.879 |
ani-1 | cyk-4 | Y49E10.19.1 | K08E3.6.2 | Anillin-like protein 1; Required for contractile events in embryos that occur prior to mitosis, such as cortical ruffling and pseudocleavage. Promotes membrane ruffling by organizing cortical patches of septins and myosin II. Not generally required for cytokinesis in mitotic cells. Required for the asymmetric cleavage events that extrude the two polar bodies during oocyte meiosis. Not required for meiotic contractile ring assembly, initiation or closure but is required for the transformation of the contractile ring from a disk above the spindle to a tube around the spindle midzone. Pro [...] | CYtoKinesis defect. | 0.969 |
ani-1 | ect-2 | Y49E10.19.1 | T19E10.1b.1 | Anillin-like protein 1; Required for contractile events in embryos that occur prior to mitosis, such as cortical ruffling and pseudocleavage. Promotes membrane ruffling by organizing cortical patches of septins and myosin II. Not generally required for cytokinesis in mitotic cells. Required for the asymmetric cleavage events that extrude the two polar bodies during oocyte meiosis. Not required for meiotic contractile ring assembly, initiation or closure but is required for the transformation of the contractile ring from a disk above the spindle to a tube around the spindle midzone. Pro [...] | ECT2 (Mammalian Rho GEF) homolog. | 0.937 |
ani-1 | nmy-2 | Y49E10.19.1 | F20G4.3.1 | Anillin-like protein 1; Required for contractile events in embryos that occur prior to mitosis, such as cortical ruffling and pseudocleavage. Promotes membrane ruffling by organizing cortical patches of septins and myosin II. Not generally required for cytokinesis in mitotic cells. Required for the asymmetric cleavage events that extrude the two polar bodies during oocyte meiosis. Not required for meiotic contractile ring assembly, initiation or closure but is required for the transformation of the contractile ring from a disk above the spindle to a tube around the spindle midzone. Pro [...] | Non-muscle MYosin; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.926 |
ani-1 | pig-1 | Y49E10.19.1 | W03G1.6c.1 | Anillin-like protein 1; Required for contractile events in embryos that occur prior to mitosis, such as cortical ruffling and pseudocleavage. Promotes membrane ruffling by organizing cortical patches of septins and myosin II. Not generally required for cytokinesis in mitotic cells. Required for the asymmetric cleavage events that extrude the two polar bodies during oocyte meiosis. Not required for meiotic contractile ring assembly, initiation or closure but is required for the transformation of the contractile ring from a disk above the spindle to a tube around the spindle midzone. Pro [...] | Maternal embryonic leucine zipper kinase; Serine/threonine-protein kinase involved in cell autonomous neuroblast asymmetric divisions that generate one precursor cell and one apoptotic cell by controlling spindle positioning, myosin distribution and the segregation of cell fate determinants. Promotes cell shedding during embryogenesis, probably through the endocytosis-mediated removal of cell adhesion molecules such as hmp-1 from the cell surface. May act downstream of par-4/strd-1/mop-25 to regulate cell shedding. | 0.817 |
ani-1 | rga-3 | Y49E10.19.1 | K09H11.3.1 | Anillin-like protein 1; Required for contractile events in embryos that occur prior to mitosis, such as cortical ruffling and pseudocleavage. Promotes membrane ruffling by organizing cortical patches of septins and myosin II. Not generally required for cytokinesis in mitotic cells. Required for the asymmetric cleavage events that extrude the two polar bodies during oocyte meiosis. Not required for meiotic contractile ring assembly, initiation or closure but is required for the transformation of the contractile ring from a disk above the spindle to a tube around the spindle midzone. Pro [...] | Rho-GAP domain-containing protein. | 0.823 |
ani-1 | rho-1 | Y49E10.19.1 | Y51H4A.3a.1 | Anillin-like protein 1; Required for contractile events in embryos that occur prior to mitosis, such as cortical ruffling and pseudocleavage. Promotes membrane ruffling by organizing cortical patches of septins and myosin II. Not generally required for cytokinesis in mitotic cells. Required for the asymmetric cleavage events that extrude the two polar bodies during oocyte meiosis. Not required for meiotic contractile ring assembly, initiation or closure but is required for the transformation of the contractile ring from a disk above the spindle to a tube around the spindle midzone. Pro [...] | Ras-like GTP-binding protein rhoA; Required for ventral migration of epidermal cells during ventral enclosure in the embryo and for cell elongation. Also required for ventral migration of P cells during larval development. Involved in asymmetric spindle positioning during anaphase and establishment of cell polarity during embryo development. In adults, involved in regulation of multiple processes including locomotion, pharyngeal pumping, fecundity, ovulation, defecation and body morphology. In body wall muscles, regulates organization of myosin thick filaments downstream of unc-89. Ass [...] | 0.899 |
ani-1 | zen-4 | Y49E10.19.1 | M03D4.1d.2 | Anillin-like protein 1; Required for contractile events in embryos that occur prior to mitosis, such as cortical ruffling and pseudocleavage. Promotes membrane ruffling by organizing cortical patches of septins and myosin II. Not generally required for cytokinesis in mitotic cells. Required for the asymmetric cleavage events that extrude the two polar bodies during oocyte meiosis. Not required for meiotic contractile ring assembly, initiation or closure but is required for the transformation of the contractile ring from a disk above the spindle to a tube around the spindle midzone. Pro [...] | Kinesin-like protein. | 0.971 |
aspm-1 | ani-1 | C45G3.1.1 | Y49E10.19.1 | Calponin-homology (CH) domain-containing protein. | Anillin-like protein 1; Required for contractile events in embryos that occur prior to mitosis, such as cortical ruffling and pseudocleavage. Promotes membrane ruffling by organizing cortical patches of septins and myosin II. Not generally required for cytokinesis in mitotic cells. Required for the asymmetric cleavage events that extrude the two polar bodies during oocyte meiosis. Not required for meiotic contractile ring assembly, initiation or closure but is required for the transformation of the contractile ring from a disk above the spindle to a tube around the spindle midzone. Pro [...] | 0.715 |
aspm-1 | bmk-1 | C45G3.1.1 | F23B12.8b.1 | Calponin-homology (CH) domain-containing protein. | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | 0.988 |
aspm-1 | cyk-1 | C45G3.1.1 | F11H8.4b.1 | Calponin-homology (CH) domain-containing protein. | CYtoKinesis defect. | 0.432 |
aspm-1 | cyk-4 | C45G3.1.1 | K08E3.6.2 | Calponin-homology (CH) domain-containing protein. | CYtoKinesis defect. | 0.716 |
aspm-1 | ect-2 | C45G3.1.1 | T19E10.1b.1 | Calponin-homology (CH) domain-containing protein. | ECT2 (Mammalian Rho GEF) homolog. | 0.872 |
aspm-1 | pig-1 | C45G3.1.1 | W03G1.6c.1 | Calponin-homology (CH) domain-containing protein. | Maternal embryonic leucine zipper kinase; Serine/threonine-protein kinase involved in cell autonomous neuroblast asymmetric divisions that generate one precursor cell and one apoptotic cell by controlling spindle positioning, myosin distribution and the segregation of cell fate determinants. Promotes cell shedding during embryogenesis, probably through the endocytosis-mediated removal of cell adhesion molecules such as hmp-1 from the cell surface. May act downstream of par-4/strd-1/mop-25 to regulate cell shedding. | 0.840 |
aspm-1 | zen-4 | C45G3.1.1 | M03D4.1d.2 | Calponin-homology (CH) domain-containing protein. | Kinesin-like protein. | 0.974 |
bmk-1 | ani-1 | F23B12.8b.1 | Y49E10.19.1 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Anillin-like protein 1; Required for contractile events in embryos that occur prior to mitosis, such as cortical ruffling and pseudocleavage. Promotes membrane ruffling by organizing cortical patches of septins and myosin II. Not generally required for cytokinesis in mitotic cells. Required for the asymmetric cleavage events that extrude the two polar bodies during oocyte meiosis. Not required for meiotic contractile ring assembly, initiation or closure but is required for the transformation of the contractile ring from a disk above the spindle to a tube around the spindle midzone. Pro [...] | 0.780 |
bmk-1 | aspm-1 | F23B12.8b.1 | C45G3.1.1 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Calponin-homology (CH) domain-containing protein. | 0.988 |
bmk-1 | cyk-1 | F23B12.8b.1 | F11H8.4b.1 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | CYtoKinesis defect. | 0.466 |