STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sptf-2SP (Specificity Protein) Transcription Factor. (166 aa)    
Predicted Functional Partners:
nhr-106
Nuclear hormone receptor family member nhr-106; Orphan nuclear receptor; Belongs to the nuclear hormone receptor family.
    
 
 0.707
oac-29
Acyl_transf_3 domain-containing protein.
   
 
 0.705
tag-164
Uncharacterized protein.
    
 
 0.702
T26E4.4
Uncharacterized protein.
    
 
 0.701
oac-30
Acyl_transf_3 domain-containing protein.
   
 
 0.697
F08G2.7
Uncharacterized protein.
      
 0.695
E03H4.4
Uncharacterized protein.
      
 0.693
elk-2
ELK transcription factor homolog.
   
  
 0.669
nspd-3
Nematode Specific Peptide family, group D.
      
 0.660
plr-1
Probable E3 ubiquitin-protein ligase plr-1; Probable E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled (By similarity). Acts on both canonical and non- canonical Wnt signaling pathway (By similarity). Plays a role in the migration and axon guidance of different neuronal cell types including CAN, HSN, AVK and AVG. Promotes the differentiation and regulates the anteroposterior polarity of AVG unpaired interneurons by sequestering the [...]
    
 
 0.620
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.