STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpl-11.160S ribosomal protein L11-1; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome throu [...] (196 aa)    
Predicted Functional Partners:
rps-30
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 
 0.999
rpl-5
60S ribosomal protein L5; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...]
  
 
 0.995
rpl-2
60S ribosomal protein L8.
  
 
 0.994
rpl-23
60S ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family.
  
 
 0.994
rpl-19
60S ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family.
  
 
 0.994
rps-3
40S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family.
  
 
 0.994
rps-2
40S ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family.
  
 
 0.994
rpl-24.1
60S ribosomal protein L24; Belongs to the eukaryotic ribosomal protein eL24 family.
   
 
 0.994
rps-15
40S ribosomal protein S15; Negatively regulates lifespan.
  
 
 0.994
rpl-7
60S ribosomal protein L7; Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs (By similarity).
  
 
 0.994
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.