STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
T25B9.1Aminotran_1_2 domain-containing protein. (403 aa)    
Predicted Functional Partners:
F08F3.4
Epimerase domain-containing protein.
  
 
 0.996
C15B12.1
Putative sarcosine oxidase; Belongs to the MSOX/MTOX family.
  
 
 0.982
R102.4
Uncharacterized protein R102.4; Belongs to the threonine aldolase family.
  
 
 0.981
gldc-1
Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.
  
 
 0.977
T09B4.8
Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.973
agxt-1
Serine--pyruvate aminotransferase.
    
 0.972
mel-32
Serine hydroxymethyltransferase; Interconversion of serine and glycine; Belongs to the SHMT family.
  
 
 0.957
daao-1
D-amino-acid oxidase; Catalyzes oxidative deamination of D-amino acids, in particular D-alanine, and could be responsible for the degradation of diet-derived D-alanine in the intestine. Acts on a variety of D-amino acids with greater preference towards those with basic and aromatic groups followed by those bearing neutral groups. Has no activity against acidic D-amino acids, L-amino acids or N-methyl-L-aspartic acid. May play a role in egg-laying events and early development.
  
 
 0.955
gcsh-1
Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.
  
 
 0.843
gcst-1
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.
  
  
 0.821
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.