node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
R06F6.8 | gdi-1 | R06F6.8b.1 | Y57G11C.10b.1 | Guanine nucleotide exchange factor subunit R06F6.8; Probable component of a guanine nucleotide exchange factor (GEF) that may be required for efficient fusion of endosome-derived vesicles with the Golgi; Belongs to the RIC1 family. | Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. | 0.460 |
R06F6.8 | rab-6.1 | R06F6.8b.1 | F59B2.7.1 | Guanine nucleotide exchange factor subunit R06F6.8; Probable component of a guanine nucleotide exchange factor (GEF) that may be required for efficient fusion of endosome-derived vesicles with the Golgi; Belongs to the RIC1 family. | Ras-related protein Rab-6.1; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. | 0.844 |
R06F6.8 | rab-6.2 | R06F6.8b.1 | T25G12.4.1 | Guanine nucleotide exchange factor subunit R06F6.8; Probable component of a guanine nucleotide exchange factor (GEF) that may be required for efficient fusion of endosome-derived vesicles with the Golgi; Belongs to the RIC1 family. | Ras-related protein Rab-6.2; Protein transport. Probably involved in vesicular traffic (By similarity). | 0.844 |
arl-1 | rab-6.1 | F54C9.10.2 | F59B2.7.1 | ADP-ribosylation factor-like protein 1; GTP-binding protein that may be involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Plays a role in male tail tip morphogenesis. | Ras-related protein Rab-6.1; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. | 0.682 |
arl-1 | rab-6.2 | F54C9.10.2 | T25G12.4.1 | ADP-ribosylation factor-like protein 1; GTP-binding protein that may be involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Plays a role in male tail tip morphogenesis. | Ras-related protein Rab-6.2; Protein transport. Probably involved in vesicular traffic (By similarity). | 0.786 |
arl-1 | vps-53 | F54C9.10.2 | T05G5.8a.1 | ADP-ribosylation factor-like protein 1; GTP-binding protein that may be involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Plays a role in male tail tip morphogenesis. | Vacuolar protein sorting-associated protein 53 homolog; Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex facilitates tethering as well as SNARE complex assembly at the Golgi. Plays a role in the trafficking of cargo to dense-core vesicles, probably through association with the EARP-interacting protein eipr-1. Important for neuronal function. | 0.402 |
bicd-1 | rab-6.1 | C43G2.2a.1 | F59B2.7.1 | Protein bicaudal D homolog; Part of a complex with dlc-1 and egal-1, which is recruited to the nuclear envelope by unc-83, where in turn, it recruits dynein to the nuclear surface and regulates nuclear migration in hypodermal precursor cells (Probable). Required for the formation of dendritic branches of PVD sensory neurons ; Belongs to the BicD family. | Ras-related protein Rab-6.1; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. | 0.878 |
bicd-1 | rab-6.2 | C43G2.2a.1 | T25G12.4.1 | Protein bicaudal D homolog; Part of a complex with dlc-1 and egal-1, which is recruited to the nuclear envelope by unc-83, where in turn, it recruits dynein to the nuclear surface and regulates nuclear migration in hypodermal precursor cells (Probable). Required for the formation of dendritic branches of PVD sensory neurons ; Belongs to the BicD family. | Ras-related protein Rab-6.2; Protein transport. Probably involved in vesicular traffic (By similarity). | 0.878 |
eat-17 | rab-6.2 | T24D11.1e.1 | T25G12.4.1 | Rab-GAP TBC domain-containing protein. | Ras-related protein Rab-6.2; Protein transport. Probably involved in vesicular traffic (By similarity). | 0.861 |
gdi-1 | R06F6.8 | Y57G11C.10b.1 | R06F6.8b.1 | Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. | Guanine nucleotide exchange factor subunit R06F6.8; Probable component of a guanine nucleotide exchange factor (GEF) that may be required for efficient fusion of endosome-derived vesicles with the Golgi; Belongs to the RIC1 family. | 0.460 |
gdi-1 | rab-6.1 | Y57G11C.10b.1 | F59B2.7.1 | Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. | Ras-related protein Rab-6.1; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. | 0.952 |
gdi-1 | rab-6.2 | Y57G11C.10b.1 | T25G12.4.1 | Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. | Ras-related protein Rab-6.2; Protein transport. Probably involved in vesicular traffic (By similarity). | 0.953 |
rab-6.1 | R06F6.8 | F59B2.7.1 | R06F6.8b.1 | Ras-related protein Rab-6.1; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. | Guanine nucleotide exchange factor subunit R06F6.8; Probable component of a guanine nucleotide exchange factor (GEF) that may be required for efficient fusion of endosome-derived vesicles with the Golgi; Belongs to the RIC1 family. | 0.844 |
rab-6.1 | arl-1 | F59B2.7.1 | F54C9.10.2 | Ras-related protein Rab-6.1; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. | ADP-ribosylation factor-like protein 1; GTP-binding protein that may be involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Plays a role in male tail tip morphogenesis. | 0.682 |
rab-6.1 | bicd-1 | F59B2.7.1 | C43G2.2a.1 | Ras-related protein Rab-6.1; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. | Protein bicaudal D homolog; Part of a complex with dlc-1 and egal-1, which is recruited to the nuclear envelope by unc-83, where in turn, it recruits dynein to the nuclear surface and regulates nuclear migration in hypodermal precursor cells (Probable). Required for the formation of dendritic branches of PVD sensory neurons ; Belongs to the BicD family. | 0.878 |
rab-6.1 | gdi-1 | F59B2.7.1 | Y57G11C.10b.1 | Ras-related protein Rab-6.1; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. | Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. | 0.952 |
rab-6.1 | rab-6.2 | F59B2.7.1 | T25G12.4.1 | Ras-related protein Rab-6.1; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. | Ras-related protein Rab-6.2; Protein transport. Probably involved in vesicular traffic (By similarity). | 0.881 |
rab-6.1 | tbc-11 | F59B2.7.1 | F35H12.2b.1 | Ras-related protein Rab-6.1; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. | Rab-GAP TBC domain-containing protein. | 0.852 |
rab-6.1 | vps-39 | F59B2.7.1 | T08G5.5b.1 | Ras-related protein Rab-6.1; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. | Vacuolar protein sorting-associated protein 39 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways (By similarity). Believed to act in part as a component of the putative HOPS endosomal tethering complex which is proposed to be involved in the rab-5-to-rab-7 endosome conversion probably implicating sand-1, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to rab-7 on th [...] | 0.870 |
rab-6.1 | vps-52 | F59B2.7.1 | F08C6.3.1 | Ras-related protein Rab-6.1; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. | Vacuolar protein sorting-associated protein 52 homolog; Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex facilitates tethering as well as SNARE complex assembly at the Golgi. Plays a role in the trafficking of cargo to dense-core vesicles, probably through association with the EARP-interacting protein eipr-1. Important for neuronal function. Belongs to the VPS52 family. | 0.758 |