Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C03B1.5 | mop-25.3 | C03B1.5.1 | T27C10.3.1 | Putative tyrosine-protein kinase C03B1.5. | MO25-like protein 3; Belongs to the Mo25 family. | 0.657 |
| C03B1.5 | sax-1 | C03B1.5.1 | R11G1.4a.1 | Putative tyrosine-protein kinase C03B1.5. | Serine/threonine-protein kinase sax-1; Acts with sax-2 to restrict the growth of both primary and secondary neurites. Regulates mechanosensory tiling by controlling the termination point of sensory dendrites; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. | 0.631 |
| gck-1 | mop-25.3 | T19A5.2b.1 | T27C10.3.1 | Germinal center kinase 1; Serine/threonine-protein kinase which is required for normal oogenesis and suppression of germline cell apoptosis. Inhibits phosphorylation and thus probably activation of mpk-1 during pachytene stage. Involved in excretory canal elongation during postembryonic development, probably acting downstream of ccm-3 ; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. | MO25-like protein 3; Belongs to the Mo25 family. | 0.662 |
| gck-1 | sax-1 | T19A5.2b.1 | R11G1.4a.1 | Germinal center kinase 1; Serine/threonine-protein kinase which is required for normal oogenesis and suppression of germline cell apoptosis. Inhibits phosphorylation and thus probably activation of mpk-1 during pachytene stage. Involved in excretory canal elongation during postembryonic development, probably acting downstream of ccm-3 ; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. | Serine/threonine-protein kinase sax-1; Acts with sax-2 to restrict the growth of both primary and secondary neurites. Regulates mechanosensory tiling by controlling the termination point of sensory dendrites; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. | 0.703 |
| hif-1 | mop-25.3 | F38A6.3b.1 | T27C10.3.1 | Hypoxia-inducible factor 1; A transcription factor which is a key regulator in various cellular processes; including environment stress resistance (oxygen levels, hydrogen sulfide and cyanide levels and heat), negative regulation of cell apoptosis in ASJ neurons by inhibition of cep-1 via transcriptional activation of tyr-2, resistance/susceptibility to pathogenic bacteria, lifespan and brood size. Involved in mediating susceptibility to enteropathogenic E.coli. Increased levels of hif-1 activity confer resistance to P.aeruginosa-mediated death but also confer susceptibility to S.aureu [...] | MO25-like protein 3; Belongs to the Mo25 family. | 0.502 |
| mans-4 | mop-25.3 | ZC410.3a.1 | T27C10.3.1 | alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. | MO25-like protein 3; Belongs to the Mo25 family. | 0.537 |
| mop-25.3 | C03B1.5 | T27C10.3.1 | C03B1.5.1 | MO25-like protein 3; Belongs to the Mo25 family. | Putative tyrosine-protein kinase C03B1.5. | 0.657 |
| mop-25.3 | gck-1 | T27C10.3.1 | T19A5.2b.1 | MO25-like protein 3; Belongs to the Mo25 family. | Germinal center kinase 1; Serine/threonine-protein kinase which is required for normal oogenesis and suppression of germline cell apoptosis. Inhibits phosphorylation and thus probably activation of mpk-1 during pachytene stage. Involved in excretory canal elongation during postembryonic development, probably acting downstream of ccm-3 ; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. | 0.662 |
| mop-25.3 | hif-1 | T27C10.3.1 | F38A6.3b.1 | MO25-like protein 3; Belongs to the Mo25 family. | Hypoxia-inducible factor 1; A transcription factor which is a key regulator in various cellular processes; including environment stress resistance (oxygen levels, hydrogen sulfide and cyanide levels and heat), negative regulation of cell apoptosis in ASJ neurons by inhibition of cep-1 via transcriptional activation of tyr-2, resistance/susceptibility to pathogenic bacteria, lifespan and brood size. Involved in mediating susceptibility to enteropathogenic E.coli. Increased levels of hif-1 activity confer resistance to P.aeruginosa-mediated death but also confer susceptibility to S.aureu [...] | 0.502 |
| mop-25.3 | mans-4 | T27C10.3.1 | ZC410.3a.1 | MO25-like protein 3; Belongs to the Mo25 family. | alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. | 0.537 |
| mop-25.3 | par-4 | T27C10.3.1 | Y59A8B.14a.1 | MO25-like protein 3; Belongs to the Mo25 family. | Serine/threonine-protein kinase par-4; Required for cytoplasmic partitioning and asymmetric cell division in early embryogenesis. Controls the asymmetric cell division of the Q.p neuroblast lineage. Involved in mediating cell polarization via regulation of anillin family scaffold proteins. Phosphorylates and restricts the asymmetry effectors mex-5 and mex-6 to the anterior cytoplasm of the zygote and maintains these phosphorylations until fertilization. May phosphorylate par-1. Required for strd-1 localization to the cell cortex of early embryos and may be required for strd-1 protein s [...] | 0.743 |
| mop-25.3 | pig-1 | T27C10.3.1 | W03G1.6c.1 | MO25-like protein 3; Belongs to the Mo25 family. | Maternal embryonic leucine zipper kinase; Serine/threonine-protein kinase involved in cell autonomous neuroblast asymmetric divisions that generate one precursor cell and one apoptotic cell by controlling spindle positioning, myosin distribution and the segregation of cell fate determinants. Promotes cell shedding during embryogenesis, probably through the endocytosis-mediated removal of cell adhesion molecules such as hmp-1 from the cell surface. May act downstream of par-4/strd-1/mop-25 to regulate cell shedding. | 0.513 |
| mop-25.3 | rog-1 | T27C10.3.1 | F54D12.6a.1 | MO25-like protein 3; Belongs to the Mo25 family. | IRS-type PTB domain-containing protein. | 0.707 |
| mop-25.3 | sax-1 | T27C10.3.1 | R11G1.4a.1 | MO25-like protein 3; Belongs to the Mo25 family. | Serine/threonine-protein kinase sax-1; Acts with sax-2 to restrict the growth of both primary and secondary neurites. Regulates mechanosensory tiling by controlling the termination point of sensory dendrites; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. | 0.510 |
| mop-25.3 | slr-2 | T27C10.3.1 | Y59A8B.13a.1 | MO25-like protein 3; Belongs to the Mo25 family. | Synthetic with Lin-35/Rb. | 0.602 |
| mop-25.3 | strd-1 | T27C10.3.1 | Y52D3.1a.1 | MO25-like protein 3; Belongs to the Mo25 family. | STE20-related kinase adapter protein strd-1; Pseudokinase which may act as an adapter for kinases sad-1 and par-4 and thereby is involved in several developmental processes. Regulates cell-autonomously both neuronal polarity and synaptic organization when bound to sad-1. Required for sad-1 localization to synapses. Required to establish germline stem cell (GSC) quiescence during dauer development, to promote cell shedding during embryogenesis and to control asymmetric cell division of the Q.p neuroblast lineage, probably when bound to par-4. May be involved in maintaining the integrity [...] | 0.850 |
| par-4 | mop-25.3 | Y59A8B.14a.1 | T27C10.3.1 | Serine/threonine-protein kinase par-4; Required for cytoplasmic partitioning and asymmetric cell division in early embryogenesis. Controls the asymmetric cell division of the Q.p neuroblast lineage. Involved in mediating cell polarization via regulation of anillin family scaffold proteins. Phosphorylates and restricts the asymmetry effectors mex-5 and mex-6 to the anterior cytoplasm of the zygote and maintains these phosphorylations until fertilization. May phosphorylate par-1. Required for strd-1 localization to the cell cortex of early embryos and may be required for strd-1 protein s [...] | MO25-like protein 3; Belongs to the Mo25 family. | 0.743 |
| par-4 | pig-1 | Y59A8B.14a.1 | W03G1.6c.1 | Serine/threonine-protein kinase par-4; Required for cytoplasmic partitioning and asymmetric cell division in early embryogenesis. Controls the asymmetric cell division of the Q.p neuroblast lineage. Involved in mediating cell polarization via regulation of anillin family scaffold proteins. Phosphorylates and restricts the asymmetry effectors mex-5 and mex-6 to the anterior cytoplasm of the zygote and maintains these phosphorylations until fertilization. May phosphorylate par-1. Required for strd-1 localization to the cell cortex of early embryos and may be required for strd-1 protein s [...] | Maternal embryonic leucine zipper kinase; Serine/threonine-protein kinase involved in cell autonomous neuroblast asymmetric divisions that generate one precursor cell and one apoptotic cell by controlling spindle positioning, myosin distribution and the segregation of cell fate determinants. Promotes cell shedding during embryogenesis, probably through the endocytosis-mediated removal of cell adhesion molecules such as hmp-1 from the cell surface. May act downstream of par-4/strd-1/mop-25 to regulate cell shedding. | 0.409 |
| par-4 | strd-1 | Y59A8B.14a.1 | Y52D3.1a.1 | Serine/threonine-protein kinase par-4; Required for cytoplasmic partitioning and asymmetric cell division in early embryogenesis. Controls the asymmetric cell division of the Q.p neuroblast lineage. Involved in mediating cell polarization via regulation of anillin family scaffold proteins. Phosphorylates and restricts the asymmetry effectors mex-5 and mex-6 to the anterior cytoplasm of the zygote and maintains these phosphorylations until fertilization. May phosphorylate par-1. Required for strd-1 localization to the cell cortex of early embryos and may be required for strd-1 protein s [...] | STE20-related kinase adapter protein strd-1; Pseudokinase which may act as an adapter for kinases sad-1 and par-4 and thereby is involved in several developmental processes. Regulates cell-autonomously both neuronal polarity and synaptic organization when bound to sad-1. Required for sad-1 localization to synapses. Required to establish germline stem cell (GSC) quiescence during dauer development, to promote cell shedding during embryogenesis and to control asymmetric cell division of the Q.p neuroblast lineage, probably when bound to par-4. May be involved in maintaining the integrity [...] | 0.988 |
| pig-1 | mop-25.3 | W03G1.6c.1 | T27C10.3.1 | Maternal embryonic leucine zipper kinase; Serine/threonine-protein kinase involved in cell autonomous neuroblast asymmetric divisions that generate one precursor cell and one apoptotic cell by controlling spindle positioning, myosin distribution and the segregation of cell fate determinants. Promotes cell shedding during embryogenesis, probably through the endocytosis-mediated removal of cell adhesion molecules such as hmp-1 from the cell surface. May act downstream of par-4/strd-1/mop-25 to regulate cell shedding. | MO25-like protein 3; Belongs to the Mo25 family. | 0.513 |
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