node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
F44E5.4 | daf-16 | F44E5.4.1 | R13H8.1h.1 | Uncharacterized protein; Belongs to the heat shock protein 70 family. | Forkhead box protein O; Forkhead-type transcription factor. Binds to the promoters of genes that contain the daf-16 binding element (DBE), TTGTTTAC, in their regulatory region. Functions in the Insulin/IGF-1-like signaling (IIS) mediated pathway which affects lipogenesis, lifespan, starvation survival, heat shock and oxidative stress responses, and dauer formation. Longevity signaling predominantly arises from expression in the intestine. Daf-16 transcriptional activity is negatively regulated by cytoplasmic sequestration by association with ftt-2. Inhibition is required for the carbon [...] | 0.403 |
F44E5.4 | hsf-1 | F44E5.4.1 | Y53C10A.12.1 | Uncharacterized protein; Belongs to the heat shock protein 70 family. | HSF_DOMAIN domain-containing protein. | 0.756 |
F44E5.4 | hsp-1 | F44E5.4.1 | F26D10.3.1 | Uncharacterized protein; Belongs to the heat shock protein 70 family. | Heat shock 70 kDa protein A. | 0.514 |
F44E5.4 | hsp-12.6 | F44E5.4.1 | F38E11.2.1 | Uncharacterized protein; Belongs to the heat shock protein 70 family. | SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. | 0.515 |
F44E5.4 | hsp-16.11 | F44E5.4.1 | T27E4.2.1 | Uncharacterized protein; Belongs to the heat shock protein 70 family. | Heat shock protein Hsp-16.1/Hsp-16.11. | 0.862 |
F44E5.4 | hsp-16.48 | F44E5.4.1 | T27E4.3.1 | Uncharacterized protein; Belongs to the heat shock protein 70 family. | Heat shock protein Hsp-16.48/Hsp-16.49; Belongs to the small heat shock protein (HSP20) family. | 0.777 |
F44E5.4 | hsp-3 | F44E5.4.1 | C15H9.6a.5 | Uncharacterized protein; Belongs to the heat shock protein 70 family. | Heat shock 70 kDa protein C; Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. | 0.773 |
F44E5.4 | hsp-70 | F44E5.4.1 | C12C8.1.1 | Uncharacterized protein; Belongs to the heat shock protein 70 family. | Heat Shock Protein; Belongs to the heat shock protein 70 family. | 0.546 |
daf-16 | F44E5.4 | R13H8.1h.1 | F44E5.4.1 | Forkhead box protein O; Forkhead-type transcription factor. Binds to the promoters of genes that contain the daf-16 binding element (DBE), TTGTTTAC, in their regulatory region. Functions in the Insulin/IGF-1-like signaling (IIS) mediated pathway which affects lipogenesis, lifespan, starvation survival, heat shock and oxidative stress responses, and dauer formation. Longevity signaling predominantly arises from expression in the intestine. Daf-16 transcriptional activity is negatively regulated by cytoplasmic sequestration by association with ftt-2. Inhibition is required for the carbon [...] | Uncharacterized protein; Belongs to the heat shock protein 70 family. | 0.403 |
daf-16 | hsf-1 | R13H8.1h.1 | Y53C10A.12.1 | Forkhead box protein O; Forkhead-type transcription factor. Binds to the promoters of genes that contain the daf-16 binding element (DBE), TTGTTTAC, in their regulatory region. Functions in the Insulin/IGF-1-like signaling (IIS) mediated pathway which affects lipogenesis, lifespan, starvation survival, heat shock and oxidative stress responses, and dauer formation. Longevity signaling predominantly arises from expression in the intestine. Daf-16 transcriptional activity is negatively regulated by cytoplasmic sequestration by association with ftt-2. Inhibition is required for the carbon [...] | HSF_DOMAIN domain-containing protein. | 0.927 |
daf-16 | hsp-1 | R13H8.1h.1 | F26D10.3.1 | Forkhead box protein O; Forkhead-type transcription factor. Binds to the promoters of genes that contain the daf-16 binding element (DBE), TTGTTTAC, in their regulatory region. Functions in the Insulin/IGF-1-like signaling (IIS) mediated pathway which affects lipogenesis, lifespan, starvation survival, heat shock and oxidative stress responses, and dauer formation. Longevity signaling predominantly arises from expression in the intestine. Daf-16 transcriptional activity is negatively regulated by cytoplasmic sequestration by association with ftt-2. Inhibition is required for the carbon [...] | Heat shock 70 kDa protein A. | 0.427 |
daf-16 | hsp-12.3 | R13H8.1h.1 | F38E11.1.1 | Forkhead box protein O; Forkhead-type transcription factor. Binds to the promoters of genes that contain the daf-16 binding element (DBE), TTGTTTAC, in their regulatory region. Functions in the Insulin/IGF-1-like signaling (IIS) mediated pathway which affects lipogenesis, lifespan, starvation survival, heat shock and oxidative stress responses, and dauer formation. Longevity signaling predominantly arises from expression in the intestine. Daf-16 transcriptional activity is negatively regulated by cytoplasmic sequestration by association with ftt-2. Inhibition is required for the carbon [...] | SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. | 0.410 |
daf-16 | hsp-12.6 | R13H8.1h.1 | F38E11.2.1 | Forkhead box protein O; Forkhead-type transcription factor. Binds to the promoters of genes that contain the daf-16 binding element (DBE), TTGTTTAC, in their regulatory region. Functions in the Insulin/IGF-1-like signaling (IIS) mediated pathway which affects lipogenesis, lifespan, starvation survival, heat shock and oxidative stress responses, and dauer formation. Longevity signaling predominantly arises from expression in the intestine. Daf-16 transcriptional activity is negatively regulated by cytoplasmic sequestration by association with ftt-2. Inhibition is required for the carbon [...] | SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. | 0.809 |
daf-16 | hsp-16.11 | R13H8.1h.1 | T27E4.2.1 | Forkhead box protein O; Forkhead-type transcription factor. Binds to the promoters of genes that contain the daf-16 binding element (DBE), TTGTTTAC, in their regulatory region. Functions in the Insulin/IGF-1-like signaling (IIS) mediated pathway which affects lipogenesis, lifespan, starvation survival, heat shock and oxidative stress responses, and dauer formation. Longevity signaling predominantly arises from expression in the intestine. Daf-16 transcriptional activity is negatively regulated by cytoplasmic sequestration by association with ftt-2. Inhibition is required for the carbon [...] | Heat shock protein Hsp-16.1/Hsp-16.11. | 0.807 |
daf-16 | hsp-16.48 | R13H8.1h.1 | T27E4.3.1 | Forkhead box protein O; Forkhead-type transcription factor. Binds to the promoters of genes that contain the daf-16 binding element (DBE), TTGTTTAC, in their regulatory region. Functions in the Insulin/IGF-1-like signaling (IIS) mediated pathway which affects lipogenesis, lifespan, starvation survival, heat shock and oxidative stress responses, and dauer formation. Longevity signaling predominantly arises from expression in the intestine. Daf-16 transcriptional activity is negatively regulated by cytoplasmic sequestration by association with ftt-2. Inhibition is required for the carbon [...] | Heat shock protein Hsp-16.48/Hsp-16.49; Belongs to the small heat shock protein (HSP20) family. | 0.543 |
daf-16 | hsp-70 | R13H8.1h.1 | C12C8.1.1 | Forkhead box protein O; Forkhead-type transcription factor. Binds to the promoters of genes that contain the daf-16 binding element (DBE), TTGTTTAC, in their regulatory region. Functions in the Insulin/IGF-1-like signaling (IIS) mediated pathway which affects lipogenesis, lifespan, starvation survival, heat shock and oxidative stress responses, and dauer formation. Longevity signaling predominantly arises from expression in the intestine. Daf-16 transcriptional activity is negatively regulated by cytoplasmic sequestration by association with ftt-2. Inhibition is required for the carbon [...] | Heat Shock Protein; Belongs to the heat shock protein 70 family. | 0.863 |
daf-16 | sip-1 | R13H8.1h.1 | F43D9.4.1 | Forkhead box protein O; Forkhead-type transcription factor. Binds to the promoters of genes that contain the daf-16 binding element (DBE), TTGTTTAC, in their regulatory region. Functions in the Insulin/IGF-1-like signaling (IIS) mediated pathway which affects lipogenesis, lifespan, starvation survival, heat shock and oxidative stress responses, and dauer formation. Longevity signaling predominantly arises from expression in the intestine. Daf-16 transcriptional activity is negatively regulated by cytoplasmic sequestration by association with ftt-2. Inhibition is required for the carbon [...] | Stress-induced protein 1; Belongs to the small heat shock protein (HSP20) family. | 0.588 |
hsf-1 | F44E5.4 | Y53C10A.12.1 | F44E5.4.1 | HSF_DOMAIN domain-containing protein. | Uncharacterized protein; Belongs to the heat shock protein 70 family. | 0.756 |
hsf-1 | daf-16 | Y53C10A.12.1 | R13H8.1h.1 | HSF_DOMAIN domain-containing protein. | Forkhead box protein O; Forkhead-type transcription factor. Binds to the promoters of genes that contain the daf-16 binding element (DBE), TTGTTTAC, in their regulatory region. Functions in the Insulin/IGF-1-like signaling (IIS) mediated pathway which affects lipogenesis, lifespan, starvation survival, heat shock and oxidative stress responses, and dauer formation. Longevity signaling predominantly arises from expression in the intestine. Daf-16 transcriptional activity is negatively regulated by cytoplasmic sequestration by association with ftt-2. Inhibition is required for the carbon [...] | 0.927 |
hsf-1 | hsp-1 | Y53C10A.12.1 | F26D10.3.1 | HSF_DOMAIN domain-containing protein. | Heat shock 70 kDa protein A. | 0.852 |