node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Y37E3.8 | jmjc-1 | Y37E3.8a.1 | T28F2.4a.1 | Ribosomal_L18e/L15P domain-containing protein; Belongs to the universal ribosomal protein uL15 family. | Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Specifically demethylates 'Lys- 4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code (By similarity). Mediates response to multiple stress stimuli, including heat shock and osmotic, oxidative, and ethanol stress; Belongs to the ROX family. NO66 subfamily. | 0.584 |
Y37E3.8 | mrpl-2 | Y37E3.8a.1 | F56B3.8a.1 | Ribosomal_L18e/L15P domain-containing protein; Belongs to the universal ribosomal protein uL15 family. | Ribosomal_L2_C domain-containing protein. | 0.909 |
Y37E3.8 | rpl-16 | Y37E3.8a.1 | M01F1.2.2 | Ribosomal_L18e/L15P domain-containing protein; Belongs to the universal ribosomal protein uL15 family. | 60S ribosomal protein L13a; Belongs to the universal ribosomal protein uL13 family. | 0.999 |
Y37E3.8 | rpl-2 | Y37E3.8a.1 | B0250.1.1 | Ribosomal_L18e/L15P domain-containing protein; Belongs to the universal ribosomal protein uL15 family. | 60S ribosomal protein L8. | 0.999 |
heh-1 | jmjc-1 | R148.6.1 | T28F2.4a.1 | Putative protein heh-1. | Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Specifically demethylates 'Lys- 4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code (By similarity). Mediates response to multiple stress stimuli, including heat shock and osmotic, oxidative, and ethanol stress; Belongs to the ROX family. NO66 subfamily. | 0.567 |
heh-1 | ttr-52 | R148.6.1 | F11F1.7.1 | Putative protein heh-1. | Transthyretin-like protein 52; Plays a role as a bridging molecule that mediates recognition and engulfment of apoptotic cells by cross-linking the surface-exposed phosphatidylserine with the extracellular domain of the phagocyte receptor ced-1. Important for the generation of extracellular phosphatidylserine vesicles that promote loss of the exoplasmic leaflet from apoptotic cells in a time-dependent manner. Required for the exposure of exoplasmic leaflet on the phagocytic cells surrounding the apoptotic cells. Does not affect the phosphatidylserine externalization in living cells. Ma [...] | 0.724 |
jmjc-1 | Y37E3.8 | T28F2.4a.1 | Y37E3.8a.1 | Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Specifically demethylates 'Lys- 4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code (By similarity). Mediates response to multiple stress stimuli, including heat shock and osmotic, oxidative, and ethanol stress; Belongs to the ROX family. NO66 subfamily. | Ribosomal_L18e/L15P domain-containing protein; Belongs to the universal ribosomal protein uL15 family. | 0.584 |
jmjc-1 | heh-1 | T28F2.4a.1 | R148.6.1 | Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Specifically demethylates 'Lys- 4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code (By similarity). Mediates response to multiple stress stimuli, including heat shock and osmotic, oxidative, and ethanol stress; Belongs to the ROX family. NO66 subfamily. | Putative protein heh-1. | 0.567 |
jmjc-1 | jmjd-2 | T28F2.4a.1 | Y48B6A.11.1 | Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Specifically demethylates 'Lys- 4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code (By similarity). Mediates response to multiple stress stimuli, including heat shock and osmotic, oxidative, and ethanol stress; Belongs to the ROX family. NO66 subfamily. | Lysine-specific demethylase 4; Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. Involved in the negative regulation of lifespan in a germline-dependent fashion. | 0.578 |
jmjc-1 | mrpl-2 | T28F2.4a.1 | F56B3.8a.1 | Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Specifically demethylates 'Lys- 4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code (By similarity). Mediates response to multiple stress stimuli, including heat shock and osmotic, oxidative, and ethanol stress; Belongs to the ROX family. NO66 subfamily. | Ribosomal_L2_C domain-containing protein. | 0.581 |
jmjc-1 | nath-10 | T28F2.4a.1 | F55A12.8.1 | Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Specifically demethylates 'Lys- 4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code (By similarity). Mediates response to multiple stress stimuli, including heat shock and osmotic, oxidative, and ethanol stress; Belongs to the ROX family. NO66 subfamily. | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. | 0.561 |
jmjc-1 | rpl-16 | T28F2.4a.1 | M01F1.2.2 | Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Specifically demethylates 'Lys- 4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code (By similarity). Mediates response to multiple stress stimuli, including heat shock and osmotic, oxidative, and ethanol stress; Belongs to the ROX family. NO66 subfamily. | 60S ribosomal protein L13a; Belongs to the universal ribosomal protein uL13 family. | 0.660 |
jmjc-1 | rpl-2 | T28F2.4a.1 | B0250.1.1 | Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Specifically demethylates 'Lys- 4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code (By similarity). Mediates response to multiple stress stimuli, including heat shock and osmotic, oxidative, and ethanol stress; Belongs to the ROX family. NO66 subfamily. | 60S ribosomal protein L8. | 0.936 |
jmjc-1 | slr-2 | T28F2.4a.1 | Y59A8B.13a.1 | Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Specifically demethylates 'Lys- 4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code (By similarity). Mediates response to multiple stress stimuli, including heat shock and osmotic, oxidative, and ethanol stress; Belongs to the ROX family. NO66 subfamily. | Synthetic with Lin-35/Rb. | 0.700 |
jmjc-1 | ttr-52 | T28F2.4a.1 | F11F1.7.1 | Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Specifically demethylates 'Lys- 4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code (By similarity). Mediates response to multiple stress stimuli, including heat shock and osmotic, oxidative, and ethanol stress; Belongs to the ROX family. NO66 subfamily. | Transthyretin-like protein 52; Plays a role as a bridging molecule that mediates recognition and engulfment of apoptotic cells by cross-linking the surface-exposed phosphatidylserine with the extracellular domain of the phagocyte receptor ced-1. Important for the generation of extracellular phosphatidylserine vesicles that promote loss of the exoplasmic leaflet from apoptotic cells in a time-dependent manner. Required for the exposure of exoplasmic leaflet on the phagocytic cells surrounding the apoptotic cells. Does not affect the phosphatidylserine externalization in living cells. Ma [...] | 0.684 |
jmjc-1 | zip-4 | T28F2.4a.1 | Y44E3B.1a.1 | Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Specifically demethylates 'Lys- 4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code (By similarity). Mediates response to multiple stress stimuli, including heat shock and osmotic, oxidative, and ethanol stress; Belongs to the ROX family. NO66 subfamily. | BZIP domain-containing protein. | 0.616 |
jmjd-2 | jmjc-1 | Y48B6A.11.1 | T28F2.4a.1 | Lysine-specific demethylase 4; Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. Involved in the negative regulation of lifespan in a germline-dependent fashion. | Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Specifically demethylates 'Lys- 4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code (By similarity). Mediates response to multiple stress stimuli, including heat shock and osmotic, oxidative, and ethanol stress; Belongs to the ROX family. NO66 subfamily. | 0.578 |
mrpl-2 | Y37E3.8 | F56B3.8a.1 | Y37E3.8a.1 | Ribosomal_L2_C domain-containing protein. | Ribosomal_L18e/L15P domain-containing protein; Belongs to the universal ribosomal protein uL15 family. | 0.909 |
mrpl-2 | jmjc-1 | F56B3.8a.1 | T28F2.4a.1 | Ribosomal_L2_C domain-containing protein. | Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Specifically demethylates 'Lys- 4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code (By similarity). Mediates response to multiple stress stimuli, including heat shock and osmotic, oxidative, and ethanol stress; Belongs to the ROX family. NO66 subfamily. | 0.581 |
mrpl-2 | rpl-16 | F56B3.8a.1 | M01F1.2.2 | Ribosomal_L2_C domain-containing protein. | 60S ribosomal protein L13a; Belongs to the universal ribosomal protein uL13 family. | 0.960 |