node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Y105E8A.3 | zipt-1 | Y105E8A.3.1 | F31C3.4.1 | SLC (SoLute Carrier) homolog. | Zrt (ZRT), Irt-(IRT-) like Protein Transporter. | 0.878 |
Y105E8A.3 | zipt-2.3 | Y105E8A.3.1 | Y54G9A.4.1 | SLC (SoLute Carrier) homolog. | Zrt (ZRT), Irt-(IRT-) like Protein Transporter. | 0.842 |
Y105E8A.3 | zipt-7.1 | Y105E8A.3.1 | T28F3.3.1 | SLC (SoLute Carrier) homolog. | Zinc transporter zipt-7.1; Zinc transporter which regulates intracellular zinc levels. Required for spermatogenesis in both hermaphrodites and males where it resides in an inactive form in immature sperm, spermatids, but is likely activated in response to reduced spe-4 and spe-6 function. Upon activation, mediates the release of zinc from internal stores in spermatids into the cytoplasm. The resulting increase in cytoplasmic zinc levels promotes spermatid activation and subsequent differentiation into mature motile sperm that are capable of fertilization. | 0.818 |
snf-10 | spe-6 | Y32F6A.2.1 | Y66D12A.20.1 | Transporter. | Serine/threonine-protein kinase spe-6; Serine/threonine-protein kinase which is involved in spermatogenesis. In spermatocytes, regulates meiosis and the localization and assembly of major sperm protein (MSP) into fibrous bodies. In addition, may suppress the initiation of spermiogenesis downstream of spe-8, spe-12, spe-27 and spe-29. | 0.818 |
snf-10 | spe-8 | Y32F6A.2.1 | F53G12.6.1 | Transporter. | Spermatocyte protein spe-8; Probable non-receptor tyrosine-protein kinase which plays a role in spermatid activation (spermiogenesis) in hermaphrodites. | 0.805 |
snf-10 | swm-1 | Y32F6A.2.1 | C25E10.9.1 | Transporter. | Serine protease inhibitor swm-1; Serine protease inhibitor (Probable). Probably by inhibiting serine protease tyr-5 in males, prevents the maturation of spermatids into mature motile spermatozoa until their transfer into a hermaphrodite. Also required for efficient sperm transfer and thus for male fertility. | 0.816 |
snf-10 | zipt-7.1 | Y32F6A.2.1 | T28F3.3.1 | Transporter. | Zinc transporter zipt-7.1; Zinc transporter which regulates intracellular zinc levels. Required for spermatogenesis in both hermaphrodites and males where it resides in an inactive form in immature sperm, spermatids, but is likely activated in response to reduced spe-4 and spe-6 function. Upon activation, mediates the release of zinc from internal stores in spermatids into the cytoplasm. The resulting increase in cytoplasmic zinc levels promotes spermatid activation and subsequent differentiation into mature motile sperm that are capable of fertilization. | 0.791 |
spe-6 | snf-10 | Y66D12A.20.1 | Y32F6A.2.1 | Serine/threonine-protein kinase spe-6; Serine/threonine-protein kinase which is involved in spermatogenesis. In spermatocytes, regulates meiosis and the localization and assembly of major sperm protein (MSP) into fibrous bodies. In addition, may suppress the initiation of spermiogenesis downstream of spe-8, spe-12, spe-27 and spe-29. | Transporter. | 0.818 |
spe-6 | spe-8 | Y66D12A.20.1 | F53G12.6.1 | Serine/threonine-protein kinase spe-6; Serine/threonine-protein kinase which is involved in spermatogenesis. In spermatocytes, regulates meiosis and the localization and assembly of major sperm protein (MSP) into fibrous bodies. In addition, may suppress the initiation of spermiogenesis downstream of spe-8, spe-12, spe-27 and spe-29. | Spermatocyte protein spe-8; Probable non-receptor tyrosine-protein kinase which plays a role in spermatid activation (spermiogenesis) in hermaphrodites. | 0.920 |
spe-6 | swm-1 | Y66D12A.20.1 | C25E10.9.1 | Serine/threonine-protein kinase spe-6; Serine/threonine-protein kinase which is involved in spermatogenesis. In spermatocytes, regulates meiosis and the localization and assembly of major sperm protein (MSP) into fibrous bodies. In addition, may suppress the initiation of spermiogenesis downstream of spe-8, spe-12, spe-27 and spe-29. | Serine protease inhibitor swm-1; Serine protease inhibitor (Probable). Probably by inhibiting serine protease tyr-5 in males, prevents the maturation of spermatids into mature motile spermatozoa until their transfer into a hermaphrodite. Also required for efficient sperm transfer and thus for male fertility. | 0.850 |
spe-6 | zip-7 | Y66D12A.20.1 | Y51H4A.4a.1 | Serine/threonine-protein kinase spe-6; Serine/threonine-protein kinase which is involved in spermatogenesis. In spermatocytes, regulates meiosis and the localization and assembly of major sperm protein (MSP) into fibrous bodies. In addition, may suppress the initiation of spermiogenesis downstream of spe-8, spe-12, spe-27 and spe-29. | BZIP domain-containing protein. | 0.533 |
spe-6 | zipt-7.1 | Y66D12A.20.1 | T28F3.3.1 | Serine/threonine-protein kinase spe-6; Serine/threonine-protein kinase which is involved in spermatogenesis. In spermatocytes, regulates meiosis and the localization and assembly of major sperm protein (MSP) into fibrous bodies. In addition, may suppress the initiation of spermiogenesis downstream of spe-8, spe-12, spe-27 and spe-29. | Zinc transporter zipt-7.1; Zinc transporter which regulates intracellular zinc levels. Required for spermatogenesis in both hermaphrodites and males where it resides in an inactive form in immature sperm, spermatids, but is likely activated in response to reduced spe-4 and spe-6 function. Upon activation, mediates the release of zinc from internal stores in spermatids into the cytoplasm. The resulting increase in cytoplasmic zinc levels promotes spermatid activation and subsequent differentiation into mature motile sperm that are capable of fertilization. | 0.764 |
spe-8 | snf-10 | F53G12.6.1 | Y32F6A.2.1 | Spermatocyte protein spe-8; Probable non-receptor tyrosine-protein kinase which plays a role in spermatid activation (spermiogenesis) in hermaphrodites. | Transporter. | 0.805 |
spe-8 | spe-6 | F53G12.6.1 | Y66D12A.20.1 | Spermatocyte protein spe-8; Probable non-receptor tyrosine-protein kinase which plays a role in spermatid activation (spermiogenesis) in hermaphrodites. | Serine/threonine-protein kinase spe-6; Serine/threonine-protein kinase which is involved in spermatogenesis. In spermatocytes, regulates meiosis and the localization and assembly of major sperm protein (MSP) into fibrous bodies. In addition, may suppress the initiation of spermiogenesis downstream of spe-8, spe-12, spe-27 and spe-29. | 0.920 |
spe-8 | swm-1 | F53G12.6.1 | C25E10.9.1 | Spermatocyte protein spe-8; Probable non-receptor tyrosine-protein kinase which plays a role in spermatid activation (spermiogenesis) in hermaphrodites. | Serine protease inhibitor swm-1; Serine protease inhibitor (Probable). Probably by inhibiting serine protease tyr-5 in males, prevents the maturation of spermatids into mature motile spermatozoa until their transfer into a hermaphrodite. Also required for efficient sperm transfer and thus for male fertility. | 0.854 |
spe-8 | zipt-7.1 | F53G12.6.1 | T28F3.3.1 | Spermatocyte protein spe-8; Probable non-receptor tyrosine-protein kinase which plays a role in spermatid activation (spermiogenesis) in hermaphrodites. | Zinc transporter zipt-7.1; Zinc transporter which regulates intracellular zinc levels. Required for spermatogenesis in both hermaphrodites and males where it resides in an inactive form in immature sperm, spermatids, but is likely activated in response to reduced spe-4 and spe-6 function. Upon activation, mediates the release of zinc from internal stores in spermatids into the cytoplasm. The resulting increase in cytoplasmic zinc levels promotes spermatid activation and subsequent differentiation into mature motile sperm that are capable of fertilization. | 0.808 |
srw-7 | zip-7 | R08F11.5.1 | Y51H4A.4a.1 | G_PROTEIN_RECEP_F1_2 domain-containing protein. | BZIP domain-containing protein. | 0.714 |
srw-7 | zipt-2.1 | R08F11.5.1 | C06G8.3b.2 | G_PROTEIN_RECEP_F1_2 domain-containing protein. | Zrt (ZRT), Irt-(IRT-) like Protein Transporter. | 0.917 |
srw-7 | zipt-2.3 | R08F11.5.1 | Y54G9A.4.1 | G_PROTEIN_RECEP_F1_2 domain-containing protein. | Zrt (ZRT), Irt-(IRT-) like Protein Transporter. | 0.853 |
srw-7 | zipt-7.1 | R08F11.5.1 | T28F3.3.1 | G_PROTEIN_RECEP_F1_2 domain-containing protein. | Zinc transporter zipt-7.1; Zinc transporter which regulates intracellular zinc levels. Required for spermatogenesis in both hermaphrodites and males where it resides in an inactive form in immature sperm, spermatids, but is likely activated in response to reduced spe-4 and spe-6 function. Upon activation, mediates the release of zinc from internal stores in spermatids into the cytoplasm. The resulting increase in cytoplasmic zinc levels promotes spermatid activation and subsequent differentiation into mature motile sperm that are capable of fertilization. | 0.812 |