STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
col-2Cuticle collagen 2; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. (301 aa)    
Predicted Functional Partners:
col-8
Cuticle collagen 8; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment.
      
 0.810
col-37
Col_cuticle_N domain-containing protein.
   
  
 0.761
cnc-9
CaeNaCin (Caenorhabditis bacteriocin).
   
  
 0.670
gst-18
Glutathione S-Transferase; Belongs to the GST superfamily.
      
 0.660
cut-1
Cuticlin-1; Component of the cuticles. It forms a ribbon approximately 2 microns wide running along the lateral lines underneath the alae. Contributes to the formation of extracellular envelopes protecting the organism from the environment.
   
 
 0.612
col-84
Col_cuticle_N domain-containing protein.
   
    0.592
gstk-2
Glutathione s-transferase kappa 2; Has roles in respiratory and lipid metabolism.
      
 0.586
grl-23
GRound-Like (Grd related).
   
 
 0.547
gst-17
Glutathione S-Transferase.
      
 0.535
col-102
Col_cuticle_N domain-containing protein.
   
    0.534
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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