STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nhr-61Nuclear hormone receptor family member nhr-61; Orphan nuclear receptor. (415 aa)    
Predicted Functional Partners:
scrm-4
Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family.
  
 
 
 0.726
kin-14
Tyrosine-protein kinase.
    
 
 0.707
srsx-34
Serpentine Receptor, class SX.
      
 0.698
nceh-1
Neutral Cholesterol Ester Hydrolase homolog.
      
 0.698
mans-3
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
      
 0.697
tsen-54
tRNA_int_end_N2 domain-containing protein.
   
  
 0.692
hrpu-1
B30.2/SPRY domain-containing protein.
      
 0.690
ceh-88
Homeobox domain-containing protein.
   
  
 0.664
cpsf-1
Probable cleavage and polyadenylation specificity factor subunit 1; CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity).
    
 
 0.664
tbx-33
Putative T-box protein 33.
      
 0.660
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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