STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hrpf-1HnRNP F homolog. (549 aa)    
Predicted Functional Partners:
rsp-5
Probable splicing factor, arginine/serine-rich 5; Plays a functionally redundant role in shifting germ cell sexual differentiation in hermaphrodites.
   
 0.911
rsp-6
Probable splicing factor, arginine/serine-rich 6; Plays a functionally redundant role in shifting germ cell sexual differentiation in hermaprodites. Required for the development of somatic gonad structures and for progression from larval stage to adulthood; Belongs to the splicing factor SR family.
   
 0.904
hrp-1
Heterogeneous nuclear ribonucleoprotein A1; This protein is a component of ribonucleosomes. Overexpression gradually increases telomere length, leading to increase lifespan.
   
 0.900
rsp-2
Probable splicing factor, arginine/serine-rich 2; Plays a functionally redundant role in spermatogenesis and growth rate control. Required for the development of somatic gonad structures and for progression from larval stage to adulthood. Belongs to the splicing factor SR family.
   
 0.888
rsp-7
Probable splicing factor, arginine/serine-rich 7.
   
 0.879
ptb-1
Putative RNA-binding protein PTB-1a.
   
 0.836
rsp-4
Probable splicing factor, arginine/serine-rich 4; May play a functionally redundant role in embryogenesis. Belongs to the splicing factor SR family.
   
 0.833
hrp-2
HnRNP A1 homolog.
   
 0.816
swp-1
Protein SWAP; It is a regulator of pre-mRNA splicing (and, possibly, of other RNA processing events). It may regulate its own expression at the level of RNA processing.
   
  
 0.811
C06A6.4
M20_dimer domain-containing protein.
      
 0.808
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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