STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpi-1Protein rpi-1. (450 aa)    
Predicted Functional Partners:
maph-9
Protein maph-9.
   
  
 0.854
famh-161
Protein fam-161.
   
  
 0.811
C56E6.4
Doublecortin domain-containing protein.
      
 0.807
cfap-36
Cilia- and flagella-associated protein 36.
   
  
 0.807
K04F10.2
Protein KIAA0556 homolog; May regulate ciliary A-tubule number and, along with arl-13, controls cilium integrity.
      
 0.766
F59G1.4
F59G1.4.
   
 
 0.708
C27F2.1
WD Repeat protein.
      
 0.699
rpi-2
Protein XRP2; Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.
   
  
 0.675
elp-1
Echinoderm microtubule-associated protein-like elp-1; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic; Belongs to the WD repeat EMAP family.
      
 0.582
rab-28
Ras-related protein Rab-28; GTPase. Intraflagellar transport (IFT) cargo that undergoes bidirectional IFT along the ciliary axoneme when in active GTP-bound state in amphid and phasmid ciliated sensory neurons. Targeting and function as IFT cargo may depend on the BBSome, an IFT cargo adapter. Does not undergo IFT when in inactive GDP-bound state. May in turn play a role in cilium structure and/or function in ciliated sensory neurons. Belongs to the small GTPase superfamily. Rab family.
   
  
 0.559
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.