node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
abf-5 | ilys-2 | T22H6.5.1 | C45G7.2.1 | AntiBacterial Factor related. | Invertebrate-type lysozyme 2; Has bacteriolytic activity against Gram-positive bacteria (By similarity). May play a role in resistance to Gram-positive bacterium S.aureus infection. | 0.586 |
abf-5 | lys-3 | T22H6.5.1 | Y22F5A.6.1 | AntiBacterial Factor related. | Lysozyme-like protein 3; Plays a role in the stress response to heavy metals such as copper, probably in a kgb-1-dependent manner. | 0.580 |
clec-172 | ilys-2 | K03H6.7.1 | C45G7.2.1 | C-type lectin domain-containing protein. | Invertebrate-type lysozyme 2; Has bacteriolytic activity against Gram-positive bacteria (By similarity). May play a role in resistance to Gram-positive bacterium S.aureus infection. | 0.570 |
clec-172 | lys-3 | K03H6.7.1 | Y22F5A.6.1 | C-type lectin domain-containing protein. | Lysozyme-like protein 3; Plays a role in the stress response to heavy metals such as copper, probably in a kgb-1-dependent manner. | 0.547 |
hpx-2 | lys-3 | F09F3.5.1 | Y22F5A.6.1 | Heme peroxidase 2 heavy chain; Peroxidase which is involved in maintaining the cuticle integrity in the hypodermis and pharynx. It thus plays a role in conferring resistance against Gram-positive bacteria such as E.faecalis, S.aureus and C.diphtheriae, and yeast such as C.albicans. | Lysozyme-like protein 3; Plays a role in the stress response to heavy metals such as copper, probably in a kgb-1-dependent manner. | 0.534 |
ilys-2 | abf-5 | C45G7.2.1 | T22H6.5.1 | Invertebrate-type lysozyme 2; Has bacteriolytic activity against Gram-positive bacteria (By similarity). May play a role in resistance to Gram-positive bacterium S.aureus infection. | AntiBacterial Factor related. | 0.586 |
ilys-2 | clec-172 | C45G7.2.1 | K03H6.7.1 | Invertebrate-type lysozyme 2; Has bacteriolytic activity against Gram-positive bacteria (By similarity). May play a role in resistance to Gram-positive bacterium S.aureus infection. | C-type lectin domain-containing protein. | 0.570 |
ilys-2 | irg-2 | C45G7.2.1 | C49G7.5.1 | Invertebrate-type lysozyme 2; Has bacteriolytic activity against Gram-positive bacteria (By similarity). May play a role in resistance to Gram-positive bacterium S.aureus infection. | Infection Response protein. | 0.583 |
ilys-2 | lys-3 | C45G7.2.1 | Y22F5A.6.1 | Invertebrate-type lysozyme 2; Has bacteriolytic activity against Gram-positive bacteria (By similarity). May play a role in resistance to Gram-positive bacterium S.aureus infection. | Lysozyme-like protein 3; Plays a role in the stress response to heavy metals such as copper, probably in a kgb-1-dependent manner. | 0.705 |
ilys-3 | lys-3 | C45G7.3.1 | Y22F5A.6.1 | Invertebrate-type lysozyme 3; Has bacteriolytic activity against Gram-positive bacteria. Plays a role in defense against bacterial pathogens. Involved in pharyngeal grinder function by enabling proper lysis of ingested bacteria; Belongs to the glycosyl hydrolase 22 family. Type-I lysozyme subfamily. | Lysozyme-like protein 3; Plays a role in the stress response to heavy metals such as copper, probably in a kgb-1-dependent manner. | 0.707 |
ilys-4 | lys-3 | C55F2.2.1 | Y22F5A.6.1 | Invertebrate LYSozyme. | Lysozyme-like protein 3; Plays a role in the stress response to heavy metals such as copper, probably in a kgb-1-dependent manner. | 0.557 |
irg-2 | ilys-2 | C49G7.5.1 | C45G7.2.1 | Infection Response protein. | Invertebrate-type lysozyme 2; Has bacteriolytic activity against Gram-positive bacteria (By similarity). May play a role in resistance to Gram-positive bacterium S.aureus infection. | 0.583 |
irg-2 | lys-3 | C49G7.5.1 | Y22F5A.6.1 | Infection Response protein. | Lysozyme-like protein 3; Plays a role in the stress response to heavy metals such as copper, probably in a kgb-1-dependent manner. | 0.494 |
kgb-1 | kreg-1 | T07A9.3.1 | F53A9.2.1 | GLH-binding kinase 1; Mitogen-activated protein kinase which is an essential component of the JNK pathway composed of mlk-1, mek-1 and kgb-1. Phosphorylates the transcription factor fos-1 which prevents fos-1 dimerization and promoter binding and results in activation of target genes including F53A9.2/kreg-1 and lys-3/kreg-2. Phosphorylates jun-1 and activates the AP-1 transcription factor which is a heterodimer of jun-1 and fos-1. Phosphorylates glh-1 in vitro which may play a role in controlling glh-1 protein levels in the germline by targeting it for degradation by the proteasome. R [...] | Protein kreg-1; Plays a role in the stress response to heavy metals such as copper, probably in a fos-1/kgb-1-dependent manner. | 0.661 |
kgb-1 | lys-3 | T07A9.3.1 | Y22F5A.6.1 | GLH-binding kinase 1; Mitogen-activated protein kinase which is an essential component of the JNK pathway composed of mlk-1, mek-1 and kgb-1. Phosphorylates the transcription factor fos-1 which prevents fos-1 dimerization and promoter binding and results in activation of target genes including F53A9.2/kreg-1 and lys-3/kreg-2. Phosphorylates jun-1 and activates the AP-1 transcription factor which is a heterodimer of jun-1 and fos-1. Phosphorylates glh-1 in vitro which may play a role in controlling glh-1 protein levels in the germline by targeting it for degradation by the proteasome. R [...] | Lysozyme-like protein 3; Plays a role in the stress response to heavy metals such as copper, probably in a kgb-1-dependent manner. | 0.694 |
kgb-1 | vhp-1 | T07A9.3.1 | F08B1.1e.1 | GLH-binding kinase 1; Mitogen-activated protein kinase which is an essential component of the JNK pathway composed of mlk-1, mek-1 and kgb-1. Phosphorylates the transcription factor fos-1 which prevents fos-1 dimerization and promoter binding and results in activation of target genes including F53A9.2/kreg-1 and lys-3/kreg-2. Phosphorylates jun-1 and activates the AP-1 transcription factor which is a heterodimer of jun-1 and fos-1. Phosphorylates glh-1 in vitro which may play a role in controlling glh-1 protein levels in the germline by targeting it for degradation by the proteasome. R [...] | Tyrosine-protein phosphatase vhp-1; Acts preferentially on the c-Jun N-terminal kinase (JNK) and p38 MAPKs. Plays an important role in the heavy metal stress response and in axon regeneration by negatively regulating the kgb-1 (JNK-like) and the pmk-1 (p38-type) MAPK signaling pathways. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | 0.996 |
kreg-1 | kgb-1 | F53A9.2.1 | T07A9.3.1 | Protein kreg-1; Plays a role in the stress response to heavy metals such as copper, probably in a fos-1/kgb-1-dependent manner. | GLH-binding kinase 1; Mitogen-activated protein kinase which is an essential component of the JNK pathway composed of mlk-1, mek-1 and kgb-1. Phosphorylates the transcription factor fos-1 which prevents fos-1 dimerization and promoter binding and results in activation of target genes including F53A9.2/kreg-1 and lys-3/kreg-2. Phosphorylates jun-1 and activates the AP-1 transcription factor which is a heterodimer of jun-1 and fos-1. Phosphorylates glh-1 in vitro which may play a role in controlling glh-1 protein levels in the germline by targeting it for degradation by the proteasome. R [...] | 0.661 |
kreg-1 | lys-3 | F53A9.2.1 | Y22F5A.6.1 | Protein kreg-1; Plays a role in the stress response to heavy metals such as copper, probably in a fos-1/kgb-1-dependent manner. | Lysozyme-like protein 3; Plays a role in the stress response to heavy metals such as copper, probably in a kgb-1-dependent manner. | 0.837 |
kreg-1 | vhp-1 | F53A9.2.1 | F08B1.1e.1 | Protein kreg-1; Plays a role in the stress response to heavy metals such as copper, probably in a fos-1/kgb-1-dependent manner. | Tyrosine-protein phosphatase vhp-1; Acts preferentially on the c-Jun N-terminal kinase (JNK) and p38 MAPKs. Plays an important role in the heavy metal stress response and in axon regeneration by negatively regulating the kgb-1 (JNK-like) and the pmk-1 (p38-type) MAPK signaling pathways. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | 0.481 |
lys-3 | abf-5 | Y22F5A.6.1 | T22H6.5.1 | Lysozyme-like protein 3; Plays a role in the stress response to heavy metals such as copper, probably in a kgb-1-dependent manner. | AntiBacterial Factor related. | 0.580 |