node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
F38B6.4 | oxi-1 | F38B6.4.1 | Y39A1C.2.1 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | HECT domain-containing protein. | 0.678 |
F52C6.3 | atg-7 | F52C6.3.1 | M7.5.1 | Ubiquitin-like domain-containing protein. | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. | 0.626 |
F52C6.3 | oxi-1 | F52C6.3.1 | Y39A1C.2.1 | Ubiquitin-like domain-containing protein. | HECT domain-containing protein. | 0.520 |
F52C6.3 | rfl-1 | F52C6.3.1 | F11H8.1.2 | Ubiquitin-like domain-containing protein. | NEDD8-activating enzyme E1 catalytic subunit; Catalytic subunit of the dimeric rfl-1 (uba-3)-ula-1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-uba-3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of ubc-12 (By similarity). Required for cytokinesis and mitotic spindle orientation during early embryogenesis. | 0.650 |
F52C6.3 | uba-5 | F52C6.3.1 | T03F1.1.2 | Ubiquitin-like domain-containing protein. | Ubiquitin-like modifier-activating enzyme 5; E1-like enzyme which activates ufm-1. Required for interaction between ufm-1 and ufc-1; Belongs to the ubiquitin-activating E1 family. UBA5 subfamily. | 0.621 |
F52C6.3 | ubq-1 | F52C6.3.1 | F25B5.4a.2 | Ubiquitin-like domain-containing protein. | Ubiquitin-related; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involved in protein degrad [...] | 0.486 |
F52C6.3 | ubq-2 | F52C6.3.1 | ZK1010.1.1 | Ubiquitin-like domain-containing protein. | Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is invol [...] | 0.920 |
atg-7 | F52C6.3 | M7.5.1 | F52C6.3.1 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. | Ubiquitin-like domain-containing protein. | 0.626 |
atg-7 | oxi-1 | M7.5.1 | Y39A1C.2.1 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. | HECT domain-containing protein. | 0.516 |
atg-7 | rfl-1 | M7.5.1 | F11H8.1.2 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. | NEDD8-activating enzyme E1 catalytic subunit; Catalytic subunit of the dimeric rfl-1 (uba-3)-ula-1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-uba-3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of ubc-12 (By similarity). Required for cytokinesis and mitotic spindle orientation during early embryogenesis. | 0.747 |
atg-7 | uba-5 | M7.5.1 | T03F1.1.2 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. | Ubiquitin-like modifier-activating enzyme 5; E1-like enzyme which activates ufm-1. Required for interaction between ufm-1 and ufc-1; Belongs to the ubiquitin-activating E1 family. UBA5 subfamily. | 0.761 |
atg-7 | ubq-1 | M7.5.1 | F25B5.4a.2 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. | Ubiquitin-related; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involved in protein degrad [...] | 0.632 |
atg-7 | ubq-2 | M7.5.1 | ZK1010.1.1 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. | Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is invol [...] | 0.754 |
egl-47 | oxi-1 | C50H2.2a.1 | Y39A1C.2.1 | Egg laying defective EGL-47A; Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. | HECT domain-containing protein. | 0.465 |
old-1 | oxi-1 | C08H9.5.1 | Y39A1C.2.1 | Tyrosine-protein kinase receptor old-1; Receptor tyrosine kinase which plays a role in promoting longevity and resistance to stresses including UV irradiation and high temperatures, probably downstream of daf-16. | HECT domain-containing protein. | 0.463 |
oxi-1 | F38B6.4 | Y39A1C.2.1 | F38B6.4.1 | HECT domain-containing protein. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.678 |
oxi-1 | F52C6.3 | Y39A1C.2.1 | F52C6.3.1 | HECT domain-containing protein. | Ubiquitin-like domain-containing protein. | 0.520 |
oxi-1 | atg-7 | Y39A1C.2.1 | M7.5.1 | HECT domain-containing protein. | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. | 0.516 |
oxi-1 | egl-47 | Y39A1C.2.1 | C50H2.2a.1 | HECT domain-containing protein. | Egg laying defective EGL-47A; Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. | 0.465 |
oxi-1 | old-1 | Y39A1C.2.1 | C08H9.5.1 | HECT domain-containing protein. | Tyrosine-protein kinase receptor old-1; Receptor tyrosine kinase which plays a role in promoting longevity and resistance to stresses including UV irradiation and high temperatures, probably downstream of daf-16. | 0.463 |