STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
clp-4Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (716 aa)    
Predicted Functional Partners:
clpr-2
Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family.
  
   
 0.883
F55A11.4
Putative calcium-binding mitochondrial carrier F55A11.4; Mitochondrial and calcium-binding carrier that catalyzes the calcium-dependent exchange of cytoplasmic glutamate with mitochondrial aspartate across the mitochondrial inner membrane.
 
  
 
 0.499
M04F3.4
Uncharacterized protein.
   
 
 0.494
K09A9.6
TPR_REGION domain-containing protein.
   
  
 0.481
Y54E10BR.5
Signal peptidase complex catalytic subunit SEC11.
      
 0.461
cal-2
CALmodulin related genes.
   
 
 0.452
cal-4
CALmodulin related genes.
   
 
 0.448
ced-3
Cell death protein 3 subunit p13; Acts as a cysteine protease in controlling programmed cell death (apoptosis) by proteolytically activating or inactivating a wide range of substrates. Component of the egl-1, ced-9, ced-4 and ced-3 apoptotic signaling cascade required for the initiation of programmed cell death in cells fated to die during embryonic and postembryonic development. During oogenesis, required for germline apoptosis downstream of ced-9 and ced-4 but independently of egl-1. By cleaving and activating ced-8, promotes phosphatidylserine exposure on the surface of apoptotic ce [...]
    
 
 0.447
cal-1
Calmodulin-like protein; This protein resembles calmodulin in sequence but possibly resembles troponin C in function.
   
 
 0.446
cmd-1
Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
   
 
 0.437
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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