STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Y43F4B.5Uncharacterized protein; Belongs to the phosphohexose mutase family. (595 aa)    
Predicted Functional Partners:
R05F9.6
Uncharacterized protein; Belongs to the phosphohexose mutase family.
  
 0.997
F09E5.3
Putative deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate.
  
 
 0.992
pygl-1
Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
  
 
 0.991
gpi-1
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.990
rpia-1
Probable-ribose 5-phosphate isomerase; Belongs to the ribose 5-phosphate isomerase family.
    
 0.988
C50D2.7
Probable ADP-dependent glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ADP as the phosphate donor. GDP and CDP can replace ADP, but with reduced efficiency (By similarity); Belongs to the ADP-dependent glucokinase family.
  
 
 0.982
F07A11.5
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
 
 0.981
K08E3.5
UTP--glucose-1-phosphate uridylyltransferase.
  
 0.980
R151.2
Pribosyltran_N domain-containing protein.
  
 0.978
tkt-1
Transket_pyr domain-containing protein.
  
 0.976
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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