STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mrp-7Uncharacterized protein. (1525 aa)    
Predicted Functional Partners:
abcf-2
ABC transporter, class F.
  
 
 0.747
abcf-3
ABC transporter, class F.
  
 
 0.734
abcf-1
ABC transporter, class F.
  
 
 0.729
plp-1
Pur alpha Like Protein.
    
 
 0.703
pmr-1
Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.
   
 
 0.703
mrp-8
Uncharacterized protein.
  
  
0.696
C06G4.4
Uncharacterized protein C06G4.4.
      
 0.678
lgc-37
Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
    
 
 0.624
abce-1
ABC transporter, class E.
   
  
 0.619
cdc-48.2
Transitional endoplasmic reticulum ATPase homolog 2; ATP-dependent chaperone which probably uses the energy provided by ATP hydrolysis to generate mechanical force to unfold substrate proteins, disassemble protein complexes, and disaggregate protein aggregates. However, able to prevent aggregation of unfolded proteins also in an ATP-independent manner. Targets polyubiquitinated proteins for proteasomal degradation by binding to 'Lys-48'-linked polyubiquitin chains. Involved in the cytoplasmic elimination of misfolded proteins exported from the ER. This pathway, known as ERAD, prevents [...]
   
 0.583
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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