node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C14B9.2 | dpy-18 | C14B9.2.1 | Y47D3B.10.1 | Probable protein disulfide-isomerase A4; Belongs to the protein disulfide isomerase family. | Prolyl 4-hydroxylase subunit alpha-1; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins; Belongs to the P4HA family. | 0.713 |
C14B9.2 | let-268 | C14B9.2.1 | F52H3.1.1 | Probable protein disulfide-isomerase A4; Belongs to the protein disulfide isomerase family. | Multifunctional procollagen lysine hydroxylase and glycosyltransferase; Multifunctional enzyme that catalyzes a series of post- translational modifications on Lys residues in procollagen. Catalyzes the formation of hydroxylysine residues in -Xaa-Lys-Gly- sequences in type IV collagens (By similarity). Transfers galactose onto hydroxylysine groups, giving rise to galactosyl 5- hydroxylysine (By similarity). Catalyzes the subsequent transfer of glucose moieties, giving rise to 1,2-glucosylgalactosyl-5-hydroxylysine residues. Essential for normal biosynthesis and secretion of type IV coll [...] | 0.576 |
C14B9.2 | phy-2 | C14B9.2.1 | F35G2.4.1 | Probable protein disulfide-isomerase A4; Belongs to the protein disulfide isomerase family. | Prolyl 4-hydroxylase subunit alpha-2; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins; Belongs to the P4HA family. | 0.788 |
F55G1.9 | M153.1 | F55G1.9.2 | M153.1.1 | Putative pyrroline-5-carboxylate reductase. | Uncharacterized protein. | 0.931 |
F55G1.9 | dpy-18 | F55G1.9.2 | Y47D3B.10.1 | Putative pyrroline-5-carboxylate reductase. | Prolyl 4-hydroxylase subunit alpha-1; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins; Belongs to the P4HA family. | 0.900 |
F55G1.9 | phy-2 | F55G1.9.2 | F35G2.4.1 | Putative pyrroline-5-carboxylate reductase. | Prolyl 4-hydroxylase subunit alpha-2; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins; Belongs to the P4HA family. | 0.900 |
F55G1.9 | prdh-1 | F55G1.9.2 | B0513.5a.1 | Putative pyrroline-5-carboxylate reductase. | Proline dehydrogenase 1, mitochondrial; Converts proline to delta-1-pyrroline-5-carboxylate (By similarity). Through proline catabolism, promotes reactive oxygen species (ROS) production and the transcription of skn-1 target genes in response to bacterial infection by P.aeruginosa. | 0.995 |
M153.1 | F55G1.9 | M153.1.1 | F55G1.9.2 | Uncharacterized protein. | Putative pyrroline-5-carboxylate reductase. | 0.931 |
M153.1 | dpy-18 | M153.1.1 | Y47D3B.10.1 | Uncharacterized protein. | Prolyl 4-hydroxylase subunit alpha-1; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins; Belongs to the P4HA family. | 0.908 |
M153.1 | phy-2 | M153.1.1 | F35G2.4.1 | Uncharacterized protein. | Prolyl 4-hydroxylase subunit alpha-2; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins; Belongs to the P4HA family. | 0.904 |
M153.1 | prdh-1 | M153.1.1 | B0513.5a.1 | Uncharacterized protein. | Proline dehydrogenase 1, mitochondrial; Converts proline to delta-1-pyrroline-5-carboxylate (By similarity). Through proline catabolism, promotes reactive oxygen species (ROS) production and the transcription of skn-1 target genes in response to bacterial infection by P.aeruginosa. | 0.988 |
dpy-11 | dpy-18 | F46E10.9.2 | Y47D3B.10.1 | Thioredoxin domain-containing protein. | Prolyl 4-hydroxylase subunit alpha-1; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins; Belongs to the P4HA family. | 0.828 |
dpy-18 | C14B9.2 | Y47D3B.10.1 | C14B9.2.1 | Prolyl 4-hydroxylase subunit alpha-1; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins; Belongs to the P4HA family. | Probable protein disulfide-isomerase A4; Belongs to the protein disulfide isomerase family. | 0.713 |
dpy-18 | F55G1.9 | Y47D3B.10.1 | F55G1.9.2 | Prolyl 4-hydroxylase subunit alpha-1; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins; Belongs to the P4HA family. | Putative pyrroline-5-carboxylate reductase. | 0.900 |
dpy-18 | M153.1 | Y47D3B.10.1 | M153.1.1 | Prolyl 4-hydroxylase subunit alpha-1; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins; Belongs to the P4HA family. | Uncharacterized protein. | 0.908 |
dpy-18 | dpy-11 | Y47D3B.10.1 | F46E10.9.2 | Prolyl 4-hydroxylase subunit alpha-1; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins; Belongs to the P4HA family. | Thioredoxin domain-containing protein. | 0.828 |
dpy-18 | let-268 | Y47D3B.10.1 | F52H3.1.1 | Prolyl 4-hydroxylase subunit alpha-1; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins; Belongs to the P4HA family. | Multifunctional procollagen lysine hydroxylase and glycosyltransferase; Multifunctional enzyme that catalyzes a series of post- translational modifications on Lys residues in procollagen. Catalyzes the formation of hydroxylysine residues in -Xaa-Lys-Gly- sequences in type IV collagens (By similarity). Transfers galactose onto hydroxylysine groups, giving rise to galactosyl 5- hydroxylysine (By similarity). Catalyzes the subsequent transfer of glucose moieties, giving rise to 1,2-glucosylgalactosyl-5-hydroxylysine residues. Essential for normal biosynthesis and secretion of type IV coll [...] | 0.865 |
dpy-18 | pdi-2 | Y47D3B.10.1 | C07A12.4a.1 | Prolyl 4-hydroxylase subunit alpha-1; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins; Belongs to the P4HA family. | Protein disulfide-isomerase 2; Involved in cuticle formation. May play a role in the unfolded protein response. Belongs to the protein disulfide isomerase family. | 0.946 |
dpy-18 | pdi-3 | Y47D3B.10.1 | H06O01.1.3 | Prolyl 4-hydroxylase subunit alpha-1; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins; Belongs to the P4HA family. | Protein disulfide-isomerase. | 0.764 |
dpy-18 | phy-2 | Y47D3B.10.1 | F35G2.4.1 | Prolyl 4-hydroxylase subunit alpha-1; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins; Belongs to the P4HA family. | Prolyl 4-hydroxylase subunit alpha-2; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins; Belongs to the P4HA family. | 0.978 |