STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Y48B6A.13Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (377 aa)    
Predicted Functional Partners:
fdps-1
Farnesyl DiPhosphate Synthetase; Belongs to the FPP/GGPP synthase family.
  
 0.999
mvk-1
MeValonate Kinase.
  
 
 0.999
idi-1
Nudix hydrolase domain-containing protein.
  
 
 0.998
F32D8.13
Uncharacterized protein.
   
 
 0.990
hmgs-1
Hydroxymethylglutaryl-CoA synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
 
 
 0.958
coq-1
COenzyme Q (Ubiquinone) biosynthesis; Belongs to the FPP/GGPP synthase family.
  
 0.954
F41E6.5
FMN hydroxy acid dehydrogenase domain-containing protein.
    
 0.954
hmgr-1
3-hydroxy-3-methylglutaryl coenzyme A reductase.
  
  
 0.928
rpl-27
60S ribosomal protein L27; Component of the large ribosomal subunit.
 
 
    0.815
dhcr-7
DeHydroCholesterol Reductase.
   
  
 0.809
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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