node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C01G6.4 | sam-10 | C01G6.4.1 | Y48C3A.8a.1 | RING-type domain-containing protein. | Single-stranded DNA-binding protein homolog sam-10; Involved cell autonomously in PLM neuron pre-synaptic differentiation by negatively regulating prk-2 expression and in neurite branch positioning. | 0.585 |
F21D5.1 | sam-10 | F21D5.1.1 | Y48C3A.8a.1 | Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O- glycosylation; Belongs to the phosphohexose mutase family. | Single-stranded DNA-binding protein homolog sam-10; Involved cell autonomously in PLM neuron pre-synaptic differentiation by negatively regulating prk-2 expression and in neurite branch positioning. | 0.493 |
ceh-14 | ldb-1 | F46C8.5.1 | F58A3.1c.1 | Homeobox protein ceh-14; Confers thermosensory function to neurons. Required for correct AFD-mediated thermotaxis. | LID domain-containing protein. | 0.842 |
ceh-14 | lim-7 | F46C8.5.1 | C04F1.3.1 | Homeobox protein ceh-14; Confers thermosensory function to neurons. Required for correct AFD-mediated thermotaxis. | LIM domain family. | 0.948 |
ceh-14 | sam-10 | F46C8.5.1 | Y48C3A.8a.1 | Homeobox protein ceh-14; Confers thermosensory function to neurons. Required for correct AFD-mediated thermotaxis. | Single-stranded DNA-binding protein homolog sam-10; Involved cell autonomously in PLM neuron pre-synaptic differentiation by negatively regulating prk-2 expression and in neurite branch positioning. | 0.674 |
ceh-14 | ttx-3 | F46C8.5.1 | C40H5.5a.1 | Homeobox protein ceh-14; Confers thermosensory function to neurons. Required for correct AFD-mediated thermotaxis. | LIM/homeobox protein ttx-3; Required for specification of the AIA and AIY interneurons and the NSM neurons. Positively regulates the expression of a number of genes including ceh-23, kal-1, hen-1, ser-2, unc-17 and sra-11 in AIY interneurons and cat-4, flp-4, bas-1, ptps-1 and mgl-1 in NSM neurons. Also acts in an autoregulatory feedback loop to maintain its own expression. Plays a role in the thermotactic response, olfactory imprinting, regulation of longevity, control of dauer formation and axon outgrowth and pathfinding. Not required for normal chemosensory behavior. | 0.415 |
ldb-1 | ceh-14 | F58A3.1c.1 | F46C8.5.1 | LID domain-containing protein. | Homeobox protein ceh-14; Confers thermosensory function to neurons. Required for correct AFD-mediated thermotaxis. | 0.842 |
ldb-1 | lim-7 | F58A3.1c.1 | C04F1.3.1 | LID domain-containing protein. | LIM domain family. | 0.902 |
ldb-1 | lin-11 | F58A3.1c.1 | ZC247.3.1 | LID domain-containing protein. | Protein lin-11; Probable transcription factor which is required for asymmetric division of vulval blast cells. Involved in olfactory plasticity probably by regulating the expression of transcription factor mbr-1 in RIF neurons. Plays a role in the chemorepulsive response toward ascaroside pheromones mediated by the ADL sensory neurons, probably by regulating E-box motif 5'-CANNTG-3' containing target genes in the ADL neurons. Plays a role in the differentiation of the ADL sensory neurons. | 0.598 |
ldb-1 | prk-2 | F58A3.1c.1 | F45H7.4.2 | LID domain-containing protein. | Serine/threonine-protein kinase prk-2; Involved in the negative regulation of synaptic differentiation in PLM neurons; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. PIM subfamily. | 0.660 |
ldb-1 | sam-10 | F58A3.1c.1 | Y48C3A.8a.1 | LID domain-containing protein. | Single-stranded DNA-binding protein homolog sam-10; Involved cell autonomously in PLM neuron pre-synaptic differentiation by negatively regulating prk-2 expression and in neurite branch positioning. | 0.980 |
ldb-1 | ttx-3 | F58A3.1c.1 | C40H5.5a.1 | LID domain-containing protein. | LIM/homeobox protein ttx-3; Required for specification of the AIA and AIY interneurons and the NSM neurons. Positively regulates the expression of a number of genes including ceh-23, kal-1, hen-1, ser-2, unc-17 and sra-11 in AIY interneurons and cat-4, flp-4, bas-1, ptps-1 and mgl-1 in NSM neurons. Also acts in an autoregulatory feedback loop to maintain its own expression. Plays a role in the thermotactic response, olfactory imprinting, regulation of longevity, control of dauer formation and axon outgrowth and pathfinding. Not required for normal chemosensory behavior. | 0.914 |
lim-7 | ceh-14 | C04F1.3.1 | F46C8.5.1 | LIM domain family. | Homeobox protein ceh-14; Confers thermosensory function to neurons. Required for correct AFD-mediated thermotaxis. | 0.948 |
lim-7 | ldb-1 | C04F1.3.1 | F58A3.1c.1 | LIM domain family. | LID domain-containing protein. | 0.902 |
lim-7 | lin-11 | C04F1.3.1 | ZC247.3.1 | LIM domain family. | Protein lin-11; Probable transcription factor which is required for asymmetric division of vulval blast cells. Involved in olfactory plasticity probably by regulating the expression of transcription factor mbr-1 in RIF neurons. Plays a role in the chemorepulsive response toward ascaroside pheromones mediated by the ADL sensory neurons, probably by regulating E-box motif 5'-CANNTG-3' containing target genes in the ADL neurons. Plays a role in the differentiation of the ADL sensory neurons. | 0.469 |
lim-7 | sam-10 | C04F1.3.1 | Y48C3A.8a.1 | LIM domain family. | Single-stranded DNA-binding protein homolog sam-10; Involved cell autonomously in PLM neuron pre-synaptic differentiation by negatively regulating prk-2 expression and in neurite branch positioning. | 0.500 |
lin-11 | ldb-1 | ZC247.3.1 | F58A3.1c.1 | Protein lin-11; Probable transcription factor which is required for asymmetric division of vulval blast cells. Involved in olfactory plasticity probably by regulating the expression of transcription factor mbr-1 in RIF neurons. Plays a role in the chemorepulsive response toward ascaroside pheromones mediated by the ADL sensory neurons, probably by regulating E-box motif 5'-CANNTG-3' containing target genes in the ADL neurons. Plays a role in the differentiation of the ADL sensory neurons. | LID domain-containing protein. | 0.598 |
lin-11 | lim-7 | ZC247.3.1 | C04F1.3.1 | Protein lin-11; Probable transcription factor which is required for asymmetric division of vulval blast cells. Involved in olfactory plasticity probably by regulating the expression of transcription factor mbr-1 in RIF neurons. Plays a role in the chemorepulsive response toward ascaroside pheromones mediated by the ADL sensory neurons, probably by regulating E-box motif 5'-CANNTG-3' containing target genes in the ADL neurons. Plays a role in the differentiation of the ADL sensory neurons. | LIM domain family. | 0.469 |
lin-11 | sam-10 | ZC247.3.1 | Y48C3A.8a.1 | Protein lin-11; Probable transcription factor which is required for asymmetric division of vulval blast cells. Involved in olfactory plasticity probably by regulating the expression of transcription factor mbr-1 in RIF neurons. Plays a role in the chemorepulsive response toward ascaroside pheromones mediated by the ADL sensory neurons, probably by regulating E-box motif 5'-CANNTG-3' containing target genes in the ADL neurons. Plays a role in the differentiation of the ADL sensory neurons. | Single-stranded DNA-binding protein homolog sam-10; Involved cell autonomously in PLM neuron pre-synaptic differentiation by negatively regulating prk-2 expression and in neurite branch positioning. | 0.513 |
mec-15 | sam-10 | T01E8.4.1 | Y48C3A.8a.1 | F-box/WD repeat-containing protein mec-15; Plays a role in mechanosensory transduction (touch sensitivity), touch receptor neuron development and synapse formation. Regulates expression of the protein snb-1 and the distribution of synaptic vesicles at synapses to promote synaptic transmission at the neuromuscular junctions of GABAergic motor neurons. | Single-stranded DNA-binding protein homolog sam-10; Involved cell autonomously in PLM neuron pre-synaptic differentiation by negatively regulating prk-2 expression and in neurite branch positioning. | 0.711 |