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rom-5 protein (Caenorhabditis elegans) - STRING interaction network
"rom-5" - Protein ROM-5 in Caenorhabditis elegans
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rom-5Protein ROM-5 (rom-5) mRNA, complete cds (325 aa)    
Predicted Functional Partners:
rom-4
RhOMboid (Drosophila) related; Protein ROM-4, isoform c (1205 aa)
     
   
  0.960
rom-3
RhOMboid (Drosophila) related; Protein ROM-3 (rom-3) mRNA, complete cds (861 aa)
     
   
  0.943
pink-1
Serine/threonine-protein kinase pink-1, mitochondrial; Protects against mitochondrial dysfunction during cellular stress, potentially by phosphorylating mitochondrial proteins (By similarity). Plays a role in mitophagy; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family (641 aa)
     
 
  0.943
rom-2
Protein ROM-2 (rom-2) mRNA, complete cds; Belongs to the peptidase S54 family (435 aa)
     
   
  0.921
rom-1
Protein ROM-1 (rom-1) mRNA, complete cds; Belongs to the peptidase S54 family (356 aa)
     
   
  0.920
eat-3
Protein EAT-3 (eat-3) mRNA, complete cds; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family (964 aa)
     
 
  0.823
fzo-1
Transmembrane GTPase fzo-1; Probable transmembrane GTPase (By similarity). Mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission (By similarity); Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. Mitofusin subfamily (774 aa)
     
 
  0.808
spg-7
AFG3-like protein spg-7; Acts as a component of the m-AAA protease complex which is an ATP-dependent metalloprotease mediating degradation of non- assembled mitochondrial inner membrane proteins (By similarity). The complex is necessary for the assembly of mitochondrial respiratory chain and ATPase complexes (By similarity). Functions both in post-translational assembly and in the turnover of mistranslated or misfolded polypeptides; In the C-terminal section; belongs to the peptidase M41 family (782 aa)
   
   
  0.771
dnj-21
Mitochondrial import inner membrane translocase subunit TIM14; Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity) (112 aa)
     
 
  0.766
ppgn-1
ParaPleGiN AAA protease family; Protein PPGN-1 (ppgn-1) mRNA, complete cds (747 aa)
   
   
  0.760
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Caenorhabditis elegans, Rhabditis elegans, roundworm
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