node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
bud-31 | cdc-5L | C07A9.2.1 | D1081.8.1 | Protein BUD31 homolog; Involved in pre-mRNA splicing process. | Cell Division Cycle related. | 0.992 |
bud-31 | eftu-2 | C07A9.2.1 | ZK328.2.1 | Protein BUD31 homolog; Involved in pre-mRNA splicing process. | Tr-type G domain-containing protein. | 0.995 |
bud-31 | let-858 | C07A9.2.1 | F33A8.1.1 | Protein BUD31 homolog; Involved in pre-mRNA splicing process. | Pre-mRNA-splicing factor CWC22 homolog; Required for pre-mRNA splicing and for exon-junction complex (EJC) assembly. Hinders EIF4A3 from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs. Through its role in EJC assembly, required for nonsense-mediated mRNA decay (By similarity). Required for early embryogenesis and tissue differentiation; Belongs to the CWC22 family. | 0.995 |
bud-31 | mog-2 | C07A9.2.1 | H20J04.8.2 | Protein BUD31 homolog; Involved in pre-mRNA splicing process. | Probable U2 small nuclear ribonucleoprotein A; This protein is associated with sn-RNP U2. It helps the A' protein to bind stem loop IV of U2 snRNA. Required maternally for early embryonic development and zygotically for germline and somatic development. Has a role in the switch from mitosis to meiosis. Might function in alternative splicing. | 0.991 |
bud-31 | prp-19 | C07A9.2.1 | T10F2.4.1 | Protein BUD31 homolog; Involved in pre-mRNA splicing process. | Pre-mRNA-processing factor 19; Probable ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Core component of the NTC/Nineteen complex which is part of the spliceosome and participates in its assembly, its remodeling and is required for its activity (By similarity). Together with emb-4, necessary for interaction of rnp-4, a probable exon junction complex component, with mRNAs and spliceosomal snRNAs. Plays a role in nuclear retention of unspliced mRNAs. Belongs to the WD repeat PRP19 family. | 0.989 |
bud-31 | prp-8 | C07A9.2.1 | C50C3.6.1 | Protein BUD31 homolog; Involved in pre-mRNA splicing process. | Pre-mRNA-splicing factor 8 homolog; Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex. Functions as scaffold that positions spliceosomal U2, U5 and U6 snRNAs at splice sites on pre-mRNA substrates, so that splicing can occur. Interacts with both the 5' and the 3' splice site. | 0.992 |
bud-31 | rsr-2 | C07A9.2.1 | Y57A10A.19.1 | Protein BUD31 homolog; Involved in pre-mRNA splicing process. | Cwf21 domain-containing protein. | 0.990 |
bud-31 | snr-2 | C07A9.2.1 | W08E3.1.1 | Protein BUD31 homolog; Involved in pre-mRNA splicing process. | Probable small nuclear ribonucleoprotein-associated protein B; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. May have a functional role in the pre-mRNA splicing or in snRNP structure (By similarity); Belongs to the snRNP SmB/SmN family. | 0.990 |
bud-31 | snrp-200 | C07A9.2.1 | Y46G5A.4.1 | Protein BUD31 homolog; Involved in pre-mRNA splicing process. | Putative U5 small nuclear ribonucleoprotein 200 kDa helicase; Putative RNA helicase involved in the second step of RNA splicing; Belongs to the helicase family. SKI2 subfamily. | 0.989 |
bud-31 | syf-2 | C07A9.2.1 | K04G7.11.1 | Protein BUD31 homolog; Involved in pre-mRNA splicing process. | Pre-mRNA-splicing factor syf-2; May be involved in pre-mRNA splicing. | 0.992 |
cdc-5L | bud-31 | D1081.8.1 | C07A9.2.1 | Cell Division Cycle related. | Protein BUD31 homolog; Involved in pre-mRNA splicing process. | 0.992 |
cdc-5L | eftu-2 | D1081.8.1 | ZK328.2.1 | Cell Division Cycle related. | Tr-type G domain-containing protein. | 0.995 |
cdc-5L | let-858 | D1081.8.1 | F33A8.1.1 | Cell Division Cycle related. | Pre-mRNA-splicing factor CWC22 homolog; Required for pre-mRNA splicing and for exon-junction complex (EJC) assembly. Hinders EIF4A3 from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs. Through its role in EJC assembly, required for nonsense-mediated mRNA decay (By similarity). Required for early embryogenesis and tissue differentiation; Belongs to the CWC22 family. | 0.995 |
cdc-5L | mog-2 | D1081.8.1 | H20J04.8.2 | Cell Division Cycle related. | Probable U2 small nuclear ribonucleoprotein A; This protein is associated with sn-RNP U2. It helps the A' protein to bind stem loop IV of U2 snRNA. Required maternally for early embryonic development and zygotically for germline and somatic development. Has a role in the switch from mitosis to meiosis. Might function in alternative splicing. | 0.988 |
cdc-5L | prp-19 | D1081.8.1 | T10F2.4.1 | Cell Division Cycle related. | Pre-mRNA-processing factor 19; Probable ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Core component of the NTC/Nineteen complex which is part of the spliceosome and participates in its assembly, its remodeling and is required for its activity (By similarity). Together with emb-4, necessary for interaction of rnp-4, a probable exon junction complex component, with mRNAs and spliceosomal snRNAs. Plays a role in nuclear retention of unspliced mRNAs. Belongs to the WD repeat PRP19 family. | 0.999 |
cdc-5L | prp-8 | D1081.8.1 | C50C3.6.1 | Cell Division Cycle related. | Pre-mRNA-splicing factor 8 homolog; Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex. Functions as scaffold that positions spliceosomal U2, U5 and U6 snRNAs at splice sites on pre-mRNA substrates, so that splicing can occur. Interacts with both the 5' and the 3' splice site. | 0.993 |
cdc-5L | rsr-2 | D1081.8.1 | Y57A10A.19.1 | Cell Division Cycle related. | Cwf21 domain-containing protein. | 0.994 |
cdc-5L | snr-2 | D1081.8.1 | W08E3.1.1 | Cell Division Cycle related. | Probable small nuclear ribonucleoprotein-associated protein B; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. May have a functional role in the pre-mRNA splicing or in snRNP structure (By similarity); Belongs to the snRNP SmB/SmN family. | 0.986 |
cdc-5L | snrp-200 | D1081.8.1 | Y46G5A.4.1 | Cell Division Cycle related. | Putative U5 small nuclear ribonucleoprotein 200 kDa helicase; Putative RNA helicase involved in the second step of RNA splicing; Belongs to the helicase family. SKI2 subfamily. | 0.991 |
cdc-5L | syf-2 | D1081.8.1 | K04G7.11.1 | Cell Division Cycle related. | Pre-mRNA-splicing factor syf-2; May be involved in pre-mRNA splicing. | 0.997 |