STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aptf-2TF_AP-2 domain-containing protein. (367 aa)    
Predicted Functional Partners:
aptf-4
TF_AP-2 domain-containing protein.
   
0.868
aptf-3
TF_AP-2 domain-containing protein.
   
0.858
nhr-125
Nuclear hormone receptor family member nhr-125; Orphan nuclear receptor; Belongs to the nuclear hormone receptor family.
    
 
 0.811
nhr-214
Nuclear Hormone Receptor family.
    
 
 0.811
nhr-27-2
HMG box domain-containing protein.
      
 0.806
nhr-105
Nuclear Hormone Receptor family.
    
 
 0.706
dpr-1
Dauer Pheromone Responsive.
    
 
 0.705
aptf-1
Transcription factor aptf-1; Transcription factor, which is required in the single sleep- active ring interneuron RIS for sleep-like behavioral quiescence induced by neuropeptide signaling in larvae. Regulates gene expression of sleep-inducing FMRFamide-like neuropeptide flp-11 in RIS.
  
  
0.684
sea-1
T-box transcription factor 18; Probable transcriptional regulator involved in developmental processes. Activates xol-1 transcription, either directly or indirectly, establishing that xol-1 acts as the master regulator to integrate both X chromosome and autosomal signals to determine sexual fate.
   
 
 0.564
lsy-27
Uncharacterized protein.
   
 
 0.560
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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