STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Y6B3B.9Uncharacterized protein. (485 aa)    
Predicted Functional Partners:
nol-9
Polynucleotide 5'-hydroxyl-kinase nol-9; Polynucleotide 5'-kinase involved in rRNA processing.
   
 0.997
pro-1
Pre-rRNA-processing protein pro-1; Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit (By similarity). Required for processing ITS2 sequences from rRNA intermediates during 26S rRNA maturation. Required in the soma to promote normal proliferation and prevent germline tumor formation. Belongs to the WD repeat IPI3/WDR18 family.
   
 0.891
Y48A6C.4
Ipi1_N domain-containing protein.
   
 0.837
lpd-6
Brix domain-containing protein.
   
  0.758
rrp-1
Ribosomal RNA processing protein 1 homolog; May be involved in the generation of 28S rRNA. Belongs to the RRP1 family.
   
  0.756
F44G4.1
Brix domain-containing protein F44G4.1.
   
 
  0.737
Y48B6A.1
Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family.
   
  0.737
C18A3.3
Probable rRNA-processing protein EBP2 homolog; Required for the processing of the 27S pre-rRNA.
   
 
  0.721
C16A3.6
Protein MAK16 homolog; Belongs to the MAK16 family.
   
 
 0.712
H06I04.3
Putative rRNA methyltransferase; Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits.
   
 
 0.706
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.