STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Y71F9B.2Phosphatidate cytidylyltransferase, mitochondrial; Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. Required for the biosynthesis of the dimeric phospholipid cardiolipin, which stabilizes supercomplexes of the mitochondrial respiratory chain in the mitochondrial inner membrane. (321 aa)    
Predicted Functional Partners:
F52C9.3
Uncharacterized protein F52C9.3.
      
 0.752
K01D12.6
Uncharacterized protein.
   
  
 0.725
F54D7.2
EthanolaminePhosphoTransferase 1 homolog.
      
 0.710
crls-1
Probable cardiolipin synthase (CMP-forming); Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
   
 
 0.697
B0334.4
PRELI/MSF1 domain-containing protein.
   
 
 0.695
pisy-1
CDP-diacylglycerol--inositol 3-phosphatidyltransferase.
   
 
 0.690
cdgs-1
Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol (PtdIns); Belongs to the CDS family.
   
 
 0.689
pgs-1
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin; Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
   
 
 0.683
acl-3
Tafazzin family protein; Belongs to the taffazin family.
   
  
 0.609
mdmh-35
Uncharacterized protein mdmh-35; Belongs to the TRIAP1/MDM35 family.
   
  
 0.569
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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