STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Y73F4A.2DOMON domain-containing protein Y73F4A.2. (168 aa)    
Predicted Functional Partners:
F35B12.3
Uncharacterized protein.
   
    0.549
ttr-21
TransThyretin-Related family domain.
   
    0.536
F14H12.3
Uncharacterized protein.
   
 
 0.536
ran-1
GTP-binding nuclear protein ran-1; Ran GTPase system comprises ran-1, ran-2 and ran-3 and is essential in nucleocytoplasmic transport. Ran-1 is a GTP-binding protein that mediates the interaction between mitotic chromosomes and kinetochore microtubules. Plays a crucial role in nuclear envelope assembly at the end of each cell division. Required for the import of protein into the nucleus and also for RNA export. RCC1 (ran-3)/Ran (ran-1) complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA.
   
 
 0.529
pqn-31
Prion-like-(Q/N-rich)-domain-bearing protein.
   
    0.473
B0228.1
Uncharacterized protein B0228.1.
   
    0.447
rsp-5
Probable splicing factor, arginine/serine-rich 5; Plays a functionally redundant role in shifting germ cell sexual differentiation in hermaphrodites.
   
 
 0.430
rsp-2
Probable splicing factor, arginine/serine-rich 2; Plays a functionally redundant role in spermatogenesis and growth rate control. Required for the development of somatic gonad structures and for progression from larval stage to adulthood. Belongs to the splicing factor SR family.
   
 
 0.430
rsp-1
Probable splicing factor, arginine/serine-rich 1; Plays a functionally redundant role in spermatogenesis and growth rate control.
   
 
 0.430
rsp-3
Probable splicing factor, arginine/serine-rich 3; Plays an essential role in embryogenesis.
   
 
 0.430
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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