node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
abcx-1 | php-3 | C56E6.1.1 | Y75B8A.1.1 | ABC transporter, eXtended. | Homeobox domain-containing protein. | 0.592 |
ceh-13 | ceh-20 | R13A5.5.2 | F31E3.1.1 | Homeobox protein ceh-13. | Homeobox protein ceh-20; Transcription factor that binds to the 5'-TGATNNAT(G/T)(G/A)- 3' PBC/Hox lineage enhancer region of sem-2 to promote cell fate specification in the postembryonic mesoderm (also known as the M lineage). Has a role in the mig-13 pathway to promote the guidance, migration and positioning of Q neuroblasts and their descendants along the anteroposterior body axis and the anterior migration of BDU interneurons. Also required for normal vulval formation. | 0.907 |
ceh-13 | ceh-40 | R13A5.5.2 | F17A2.5.1 | Homeobox protein ceh-13. | Homeobox protein ceh-40; Belongs to the TALE/PBX homeobox family. | 0.805 |
ceh-13 | ceh-60 | R13A5.5.2 | F22A3.5.1 | Homeobox protein ceh-13. | Homeobox domain-containing protein. | 0.598 |
ceh-13 | egl-5 | R13A5.5.2 | C08C3.1b.1 | Homeobox protein ceh-13. | Homeobox protein egl-5; Essential for the determination of specific neurons. | 0.425 |
ceh-13 | lin-39 | R13A5.5.2 | C07H6.7.2 | Homeobox protein ceh-13. | Homeobox protein lin-39; Transcription factor that binds to the consensus 5'- TGATNNAT(G/T)(G/A)-3' PBC/Hox motif of target genes to regulate gene expression. Binds to the consensus PBC/Hox motif lineage enhancer region of sem-2 to promote cell fate specification in the postembryonic mesoderm (also known as the M lineage). Regulates the expression of mig-13 which controls the asymmetric distribution of actin cytoskeleton-binding protein cor-1 in Q neuroblasts. This in turn controls the polarity migration of Q neuroblasts and the subsequent mid-body region-specific development. Belongs [...] | 0.410 |
ceh-13 | mab-5 | R13A5.5.2 | C08C3.3.1 | Homeobox protein ceh-13. | Homeobox protein mab-5; Transcription factor that binds to the promoter region of the transcription factor lin-39 to repress its expression in Q neuroblasts and thereby direct left Q neuroblast (QL) daughter cell migration. During postembryonic development, required for posterior-specific pattern formation. Within the posterior body region, controls epidermal, neuronal, and mesodermal cell differentiation. Belongs to the Antp homeobox family. | 0.421 |
ceh-13 | php-3 | R13A5.5.2 | Y75B8A.1.1 | Homeobox protein ceh-13. | Homeobox domain-containing protein. | 0.583 |
ceh-13 | unc-62 | R13A5.5.2 | T28F12.2a.2 | Homeobox protein ceh-13. | Homeobox protein unc-62; Acts redundantly with ceh-20 and ceh-40 to perform overlapping roles during embryogenesis. Required for postembryonic development of the ectoderm, including the Q, V and P cell lineages, playing a crucial role in ensuring that these cells and their descendants undergo their invariant patterns of cell division, migration, fusion and morphogenesis. Has a role in the mig-13 pathway to promote anterior migration of neuroblasts in the Q lineage. Required for multiple roles in regulating vulva development. Belongs to the TALE/MEIS homeobox family. | 0.595 |
ceh-20 | ceh-13 | F31E3.1.1 | R13A5.5.2 | Homeobox protein ceh-20; Transcription factor that binds to the 5'-TGATNNAT(G/T)(G/A)- 3' PBC/Hox lineage enhancer region of sem-2 to promote cell fate specification in the postembryonic mesoderm (also known as the M lineage). Has a role in the mig-13 pathway to promote the guidance, migration and positioning of Q neuroblasts and their descendants along the anteroposterior body axis and the anterior migration of BDU interneurons. Also required for normal vulval formation. | Homeobox protein ceh-13. | 0.907 |
ceh-20 | egl-5 | F31E3.1.1 | C08C3.1b.1 | Homeobox protein ceh-20; Transcription factor that binds to the 5'-TGATNNAT(G/T)(G/A)- 3' PBC/Hox lineage enhancer region of sem-2 to promote cell fate specification in the postembryonic mesoderm (also known as the M lineage). Has a role in the mig-13 pathway to promote the guidance, migration and positioning of Q neuroblasts and their descendants along the anteroposterior body axis and the anterior migration of BDU interneurons. Also required for normal vulval formation. | Homeobox protein egl-5; Essential for the determination of specific neurons. | 0.843 |
ceh-20 | lin-39 | F31E3.1.1 | C07H6.7.2 | Homeobox protein ceh-20; Transcription factor that binds to the 5'-TGATNNAT(G/T)(G/A)- 3' PBC/Hox lineage enhancer region of sem-2 to promote cell fate specification in the postembryonic mesoderm (also known as the M lineage). Has a role in the mig-13 pathway to promote the guidance, migration and positioning of Q neuroblasts and their descendants along the anteroposterior body axis and the anterior migration of BDU interneurons. Also required for normal vulval formation. | Homeobox protein lin-39; Transcription factor that binds to the consensus 5'- TGATNNAT(G/T)(G/A)-3' PBC/Hox motif of target genes to regulate gene expression. Binds to the consensus PBC/Hox motif lineage enhancer region of sem-2 to promote cell fate specification in the postembryonic mesoderm (also known as the M lineage). Regulates the expression of mig-13 which controls the asymmetric distribution of actin cytoskeleton-binding protein cor-1 in Q neuroblasts. This in turn controls the polarity migration of Q neuroblasts and the subsequent mid-body region-specific development. Belongs [...] | 0.931 |
ceh-20 | mab-5 | F31E3.1.1 | C08C3.3.1 | Homeobox protein ceh-20; Transcription factor that binds to the 5'-TGATNNAT(G/T)(G/A)- 3' PBC/Hox lineage enhancer region of sem-2 to promote cell fate specification in the postembryonic mesoderm (also known as the M lineage). Has a role in the mig-13 pathway to promote the guidance, migration and positioning of Q neuroblasts and their descendants along the anteroposterior body axis and the anterior migration of BDU interneurons. Also required for normal vulval formation. | Homeobox protein mab-5; Transcription factor that binds to the promoter region of the transcription factor lin-39 to repress its expression in Q neuroblasts and thereby direct left Q neuroblast (QL) daughter cell migration. During postembryonic development, required for posterior-specific pattern formation. Within the posterior body region, controls epidermal, neuronal, and mesodermal cell differentiation. Belongs to the Antp homeobox family. | 0.922 |
ceh-20 | php-3 | F31E3.1.1 | Y75B8A.1.1 | Homeobox protein ceh-20; Transcription factor that binds to the 5'-TGATNNAT(G/T)(G/A)- 3' PBC/Hox lineage enhancer region of sem-2 to promote cell fate specification in the postembryonic mesoderm (also known as the M lineage). Has a role in the mig-13 pathway to promote the guidance, migration and positioning of Q neuroblasts and their descendants along the anteroposterior body axis and the anterior migration of BDU interneurons. Also required for normal vulval formation. | Homeobox domain-containing protein. | 0.927 |
ceh-20 | unc-62 | F31E3.1.1 | T28F12.2a.2 | Homeobox protein ceh-20; Transcription factor that binds to the 5'-TGATNNAT(G/T)(G/A)- 3' PBC/Hox lineage enhancer region of sem-2 to promote cell fate specification in the postembryonic mesoderm (also known as the M lineage). Has a role in the mig-13 pathway to promote the guidance, migration and positioning of Q neuroblasts and their descendants along the anteroposterior body axis and the anterior migration of BDU interneurons. Also required for normal vulval formation. | Homeobox protein unc-62; Acts redundantly with ceh-20 and ceh-40 to perform overlapping roles during embryogenesis. Required for postembryonic development of the ectoderm, including the Q, V and P cell lineages, playing a crucial role in ensuring that these cells and their descendants undergo their invariant patterns of cell division, migration, fusion and morphogenesis. Has a role in the mig-13 pathway to promote anterior migration of neuroblasts in the Q lineage. Required for multiple roles in regulating vulva development. Belongs to the TALE/MEIS homeobox family. | 0.975 |
ceh-40 | ceh-13 | F17A2.5.1 | R13A5.5.2 | Homeobox protein ceh-40; Belongs to the TALE/PBX homeobox family. | Homeobox protein ceh-13. | 0.805 |
ceh-40 | ceh-60 | F17A2.5.1 | F22A3.5.1 | Homeobox protein ceh-40; Belongs to the TALE/PBX homeobox family. | Homeobox domain-containing protein. | 0.414 |
ceh-40 | egl-5 | F17A2.5.1 | C08C3.1b.1 | Homeobox protein ceh-40; Belongs to the TALE/PBX homeobox family. | Homeobox protein egl-5; Essential for the determination of specific neurons. | 0.662 |
ceh-40 | lin-39 | F17A2.5.1 | C07H6.7.2 | Homeobox protein ceh-40; Belongs to the TALE/PBX homeobox family. | Homeobox protein lin-39; Transcription factor that binds to the consensus 5'- TGATNNAT(G/T)(G/A)-3' PBC/Hox motif of target genes to regulate gene expression. Binds to the consensus PBC/Hox motif lineage enhancer region of sem-2 to promote cell fate specification in the postembryonic mesoderm (also known as the M lineage). Regulates the expression of mig-13 which controls the asymmetric distribution of actin cytoskeleton-binding protein cor-1 in Q neuroblasts. This in turn controls the polarity migration of Q neuroblasts and the subsequent mid-body region-specific development. Belongs [...] | 0.703 |
ceh-40 | mab-5 | F17A2.5.1 | C08C3.3.1 | Homeobox protein ceh-40; Belongs to the TALE/PBX homeobox family. | Homeobox protein mab-5; Transcription factor that binds to the promoter region of the transcription factor lin-39 to repress its expression in Q neuroblasts and thereby direct left Q neuroblast (QL) daughter cell migration. During postembryonic development, required for posterior-specific pattern formation. Within the posterior body region, controls epidermal, neuronal, and mesodermal cell differentiation. Belongs to the Antp homeobox family. | 0.662 |