node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ceh-19 | lury-1 | F20D12.6b.1 | Y75B8A.11a.1 | Homeobox protein ceh-19. | Luqin-like RYamide peptides lury-1; [LURY-1-1]: Acts as a ligand for the npr-22 receptor and controls food-related processes including feeding, lifespan, egg-laying and roaming behavior. Secreted in the presence of food, leading to reduced feeding and roaming behavior and increased egg laying and lifespan. Activity may be latent under normal conditions but induced under conditions that cause hyperactivation of the pharynx such as abrupt refeeding after starvation. | 0.660 |
flp-12 | flp-15 | C05E11.8a.1 | ZK525.1.1 | FMRFamide-like peptide 12. | FMRF-Like Peptide. | 0.764 |
flp-12 | flp-7 | C05E11.8a.1 | F49E10.3.1 | FMRFamide-like peptide 12. | FMRFamide-like neuropeptides 7; FMRFamides and FMRFamide-like peptides are neuropeptides. flp-7 stimulates serotonin-induced fat loss by binding to and activating the npr-22 receptor which leads to induction of the atgl-1 lipase and subsequent fat loss. SPMQRSSMVRF-amide: Acts as a ligand for the npr-22 receptor in vitro. [SPMDRSKMVRF-amide]: Acts as a ligand for the npr-22 receptor in vitro. | 0.894 |
flp-12 | lury-1 | C05E11.8a.1 | Y75B8A.11a.1 | FMRFamide-like peptide 12. | Luqin-like RYamide peptides lury-1; [LURY-1-1]: Acts as a ligand for the npr-22 receptor and controls food-related processes including feeding, lifespan, egg-laying and roaming behavior. Secreted in the presence of food, leading to reduced feeding and roaming behavior and increased egg laying and lifespan. Activity may be latent under normal conditions but induced under conditions that cause hyperactivation of the pharynx such as abrupt refeeding after starvation. | 0.407 |
flp-15 | flp-12 | ZK525.1.1 | C05E11.8a.1 | FMRF-Like Peptide. | FMRFamide-like peptide 12. | 0.764 |
flp-15 | flp-7 | ZK525.1.1 | F49E10.3.1 | FMRF-Like Peptide. | FMRFamide-like neuropeptides 7; FMRFamides and FMRFamide-like peptides are neuropeptides. flp-7 stimulates serotonin-induced fat loss by binding to and activating the npr-22 receptor which leads to induction of the atgl-1 lipase and subsequent fat loss. SPMQRSSMVRF-amide: Acts as a ligand for the npr-22 receptor in vitro. [SPMDRSKMVRF-amide]: Acts as a ligand for the npr-22 receptor in vitro. | 0.731 |
flp-15 | gur-3 | ZK525.1.1 | ZC504.5.1 | FMRF-Like Peptide. | Gustatory receptor family protein 3; Chemoreceptor involved in light-induced avoidance behavior. Probably acts as a molecular sensor in I2 pharyngeal neurons, required for the inhibition of feeding in response to light and hydrogen peroxide. Involved in circadian rhythms, probably by acting as a light sensor. In contrast to lite-1, does not act as a photoreceptor. | 0.660 |
flp-15 | lury-1 | ZK525.1.1 | Y75B8A.11a.1 | FMRF-Like Peptide. | Luqin-like RYamide peptides lury-1; [LURY-1-1]: Acts as a ligand for the npr-22 receptor and controls food-related processes including feeding, lifespan, egg-laying and roaming behavior. Secreted in the presence of food, leading to reduced feeding and roaming behavior and increased egg laying and lifespan. Activity may be latent under normal conditions but induced under conditions that cause hyperactivation of the pharynx such as abrupt refeeding after starvation. | 0.494 |
flp-15 | npr-22 | ZK525.1.1 | Y59H11AL.1b.1 | FMRF-Like Peptide. | Neuropeptide receptor 22; Receptor for the LURY-1-1 and LURY-1-2 peptides which control food-related processes including feeding, lifespan, egg-laying and roaming behavior. Receptor for flp-7 which stimulates serotonin-induced fat loss. Serotonin induces secretion of flp-7 from neurons and binding to npr-22 which leads to induction of the atgp-1 lipase and subsequent fat loss. Acts in vitro as a receptor for the flp-7 FMRFamide- like neuropeptides TPMQRSSMVRF-amide, SPMQRSSMVRF-amide, SPMERSAMVRF- amide and SPMDRSKMVRF-amide. Also acts in vitro as a receptor for a number of other FMRFa [...] | 0.695 |
flp-7 | flp-12 | F49E10.3.1 | C05E11.8a.1 | FMRFamide-like neuropeptides 7; FMRFamides and FMRFamide-like peptides are neuropeptides. flp-7 stimulates serotonin-induced fat loss by binding to and activating the npr-22 receptor which leads to induction of the atgl-1 lipase and subsequent fat loss. SPMQRSSMVRF-amide: Acts as a ligand for the npr-22 receptor in vitro. [SPMDRSKMVRF-amide]: Acts as a ligand for the npr-22 receptor in vitro. | FMRFamide-like peptide 12. | 0.894 |
flp-7 | flp-15 | F49E10.3.1 | ZK525.1.1 | FMRFamide-like neuropeptides 7; FMRFamides and FMRFamide-like peptides are neuropeptides. flp-7 stimulates serotonin-induced fat loss by binding to and activating the npr-22 receptor which leads to induction of the atgl-1 lipase and subsequent fat loss. SPMQRSSMVRF-amide: Acts as a ligand for the npr-22 receptor in vitro. [SPMDRSKMVRF-amide]: Acts as a ligand for the npr-22 receptor in vitro. | FMRF-Like Peptide. | 0.731 |
flp-7 | lury-1 | F49E10.3.1 | Y75B8A.11a.1 | FMRFamide-like neuropeptides 7; FMRFamides and FMRFamide-like peptides are neuropeptides. flp-7 stimulates serotonin-induced fat loss by binding to and activating the npr-22 receptor which leads to induction of the atgl-1 lipase and subsequent fat loss. SPMQRSSMVRF-amide: Acts as a ligand for the npr-22 receptor in vitro. [SPMDRSKMVRF-amide]: Acts as a ligand for the npr-22 receptor in vitro. | Luqin-like RYamide peptides lury-1; [LURY-1-1]: Acts as a ligand for the npr-22 receptor and controls food-related processes including feeding, lifespan, egg-laying and roaming behavior. Secreted in the presence of food, leading to reduced feeding and roaming behavior and increased egg laying and lifespan. Activity may be latent under normal conditions but induced under conditions that cause hyperactivation of the pharynx such as abrupt refeeding after starvation. | 0.725 |
flp-7 | npr-22 | F49E10.3.1 | Y59H11AL.1b.1 | FMRFamide-like neuropeptides 7; FMRFamides and FMRFamide-like peptides are neuropeptides. flp-7 stimulates serotonin-induced fat loss by binding to and activating the npr-22 receptor which leads to induction of the atgl-1 lipase and subsequent fat loss. SPMQRSSMVRF-amide: Acts as a ligand for the npr-22 receptor in vitro. [SPMDRSKMVRF-amide]: Acts as a ligand for the npr-22 receptor in vitro. | Neuropeptide receptor 22; Receptor for the LURY-1-1 and LURY-1-2 peptides which control food-related processes including feeding, lifespan, egg-laying and roaming behavior. Receptor for flp-7 which stimulates serotonin-induced fat loss. Serotonin induces secretion of flp-7 from neurons and binding to npr-22 which leads to induction of the atgp-1 lipase and subsequent fat loss. Acts in vitro as a receptor for the flp-7 FMRFamide- like neuropeptides TPMQRSSMVRF-amide, SPMQRSSMVRF-amide, SPMERSAMVRF- amide and SPMDRSKMVRF-amide. Also acts in vitro as a receptor for a number of other FMRFa [...] | 0.950 |
flp-7 | tkr-1 | F49E10.3.1 | C38C10.1.1 | FMRFamide-like neuropeptides 7; FMRFamides and FMRFamide-like peptides are neuropeptides. flp-7 stimulates serotonin-induced fat loss by binding to and activating the npr-22 receptor which leads to induction of the atgl-1 lipase and subsequent fat loss. SPMQRSSMVRF-amide: Acts as a ligand for the npr-22 receptor in vitro. [SPMDRSKMVRF-amide]: Acts as a ligand for the npr-22 receptor in vitro. | Probable G-protein coupled receptor tkr-1; Not known. Putative receptor; Belongs to the G-protein coupled receptor 1 family. | 0.541 |
gur-3 | flp-15 | ZC504.5.1 | ZK525.1.1 | Gustatory receptor family protein 3; Chemoreceptor involved in light-induced avoidance behavior. Probably acts as a molecular sensor in I2 pharyngeal neurons, required for the inhibition of feeding in response to light and hydrogen peroxide. Involved in circadian rhythms, probably by acting as a light sensor. In contrast to lite-1, does not act as a photoreceptor. | FMRF-Like Peptide. | 0.660 |
gur-3 | lury-1 | ZC504.5.1 | Y75B8A.11a.1 | Gustatory receptor family protein 3; Chemoreceptor involved in light-induced avoidance behavior. Probably acts as a molecular sensor in I2 pharyngeal neurons, required for the inhibition of feeding in response to light and hydrogen peroxide. Involved in circadian rhythms, probably by acting as a light sensor. In contrast to lite-1, does not act as a photoreceptor. | Luqin-like RYamide peptides lury-1; [LURY-1-1]: Acts as a ligand for the npr-22 receptor and controls food-related processes including feeding, lifespan, egg-laying and roaming behavior. Secreted in the presence of food, leading to reduced feeding and roaming behavior and increased egg laying and lifespan. Activity may be latent under normal conditions but induced under conditions that cause hyperactivation of the pharynx such as abrupt refeeding after starvation. | 0.660 |
lury-1 | ceh-19 | Y75B8A.11a.1 | F20D12.6b.1 | Luqin-like RYamide peptides lury-1; [LURY-1-1]: Acts as a ligand for the npr-22 receptor and controls food-related processes including feeding, lifespan, egg-laying and roaming behavior. Secreted in the presence of food, leading to reduced feeding and roaming behavior and increased egg laying and lifespan. Activity may be latent under normal conditions but induced under conditions that cause hyperactivation of the pharynx such as abrupt refeeding after starvation. | Homeobox protein ceh-19. | 0.660 |
lury-1 | flp-12 | Y75B8A.11a.1 | C05E11.8a.1 | Luqin-like RYamide peptides lury-1; [LURY-1-1]: Acts as a ligand for the npr-22 receptor and controls food-related processes including feeding, lifespan, egg-laying and roaming behavior. Secreted in the presence of food, leading to reduced feeding and roaming behavior and increased egg laying and lifespan. Activity may be latent under normal conditions but induced under conditions that cause hyperactivation of the pharynx such as abrupt refeeding after starvation. | FMRFamide-like peptide 12. | 0.407 |
lury-1 | flp-15 | Y75B8A.11a.1 | ZK525.1.1 | Luqin-like RYamide peptides lury-1; [LURY-1-1]: Acts as a ligand for the npr-22 receptor and controls food-related processes including feeding, lifespan, egg-laying and roaming behavior. Secreted in the presence of food, leading to reduced feeding and roaming behavior and increased egg laying and lifespan. Activity may be latent under normal conditions but induced under conditions that cause hyperactivation of the pharynx such as abrupt refeeding after starvation. | FMRF-Like Peptide. | 0.494 |
lury-1 | flp-7 | Y75B8A.11a.1 | F49E10.3.1 | Luqin-like RYamide peptides lury-1; [LURY-1-1]: Acts as a ligand for the npr-22 receptor and controls food-related processes including feeding, lifespan, egg-laying and roaming behavior. Secreted in the presence of food, leading to reduced feeding and roaming behavior and increased egg laying and lifespan. Activity may be latent under normal conditions but induced under conditions that cause hyperactivation of the pharynx such as abrupt refeeding after starvation. | FMRFamide-like neuropeptides 7; FMRFamides and FMRFamide-like peptides are neuropeptides. flp-7 stimulates serotonin-induced fat loss by binding to and activating the npr-22 receptor which leads to induction of the atgl-1 lipase and subsequent fat loss. SPMQRSSMVRF-amide: Acts as a ligand for the npr-22 receptor in vitro. [SPMDRSKMVRF-amide]: Acts as a ligand for the npr-22 receptor in vitro. | 0.725 |