node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ceh-20 | nob-1 | F31E3.1.1 | Y75B8A.2a.1 | Homeobox protein ceh-20; Transcription factor that binds to the 5'-TGATNNAT(G/T)(G/A)- 3' PBC/Hox lineage enhancer region of sem-2 to promote cell fate specification in the postembryonic mesoderm (also known as the M lineage). Has a role in the mig-13 pathway to promote the guidance, migration and positioning of Q neuroblasts and their descendants along the anteroposterior body axis and the anterior migration of BDU interneurons. Also required for normal vulval formation. | Homeobox domain-containing protein. | 0.898 |
ceh-20 | psa-3 | F31E3.1.1 | F39D8.2a.1 | Homeobox protein ceh-20; Transcription factor that binds to the 5'-TGATNNAT(G/T)(G/A)- 3' PBC/Hox lineage enhancer region of sem-2 to promote cell fate specification in the postembryonic mesoderm (also known as the M lineage). Has a role in the mig-13 pathway to promote the guidance, migration and positioning of Q neuroblasts and their descendants along the anteroposterior body axis and the anterior migration of BDU interneurons. Also required for normal vulval formation. | Meis_PKNOX_N domain-containing protein. | 0.898 |
ceh-20 | unc-62 | F31E3.1.1 | T28F12.2a.2 | Homeobox protein ceh-20; Transcription factor that binds to the 5'-TGATNNAT(G/T)(G/A)- 3' PBC/Hox lineage enhancer region of sem-2 to promote cell fate specification in the postembryonic mesoderm (also known as the M lineage). Has a role in the mig-13 pathway to promote the guidance, migration and positioning of Q neuroblasts and their descendants along the anteroposterior body axis and the anterior migration of BDU interneurons. Also required for normal vulval formation. | Homeobox protein unc-62; Acts redundantly with ceh-20 and ceh-40 to perform overlapping roles during embryogenesis. Required for postembryonic development of the ectoderm, including the Q, V and P cell lineages, playing a crucial role in ensuring that these cells and their descendants undergo their invariant patterns of cell division, migration, fusion and morphogenesis. Has a role in the mig-13 pathway to promote anterior migration of neuroblasts in the Q lineage. Required for multiple roles in regulating vulva development. Belongs to the TALE/MEIS homeobox family. | 0.975 |
ceh-40 | ceh-60 | F17A2.5.1 | F22A3.5.1 | Homeobox protein ceh-40; Belongs to the TALE/PBX homeobox family. | Homeobox domain-containing protein. | 0.414 |
ceh-40 | nob-1 | F17A2.5.1 | Y75B8A.2a.1 | Homeobox protein ceh-40; Belongs to the TALE/PBX homeobox family. | Homeobox domain-containing protein. | 0.892 |
ceh-40 | psa-3 | F17A2.5.1 | F39D8.2a.1 | Homeobox protein ceh-40; Belongs to the TALE/PBX homeobox family. | Meis_PKNOX_N domain-containing protein. | 0.750 |
ceh-40 | tbx-9 | F17A2.5.1 | T07C4.6.1 | Homeobox protein ceh-40; Belongs to the TALE/PBX homeobox family. | T-box transcription factor tbx-9; Involved in the control of early morphogenesis of the intestine, hypodermis and body-wall muscle. Appears to have partially redundant function to tbx-8. | 0.554 |
ceh-40 | unc-62 | F17A2.5.1 | T28F12.2a.2 | Homeobox protein ceh-40; Belongs to the TALE/PBX homeobox family. | Homeobox protein unc-62; Acts redundantly with ceh-20 and ceh-40 to perform overlapping roles during embryogenesis. Required for postembryonic development of the ectoderm, including the Q, V and P cell lineages, playing a crucial role in ensuring that these cells and their descendants undergo their invariant patterns of cell division, migration, fusion and morphogenesis. Has a role in the mig-13 pathway to promote anterior migration of neuroblasts in the Q lineage. Required for multiple roles in regulating vulva development. Belongs to the TALE/MEIS homeobox family. | 0.953 |
ceh-60 | ceh-40 | F22A3.5.1 | F17A2.5.1 | Homeobox domain-containing protein. | Homeobox protein ceh-40; Belongs to the TALE/PBX homeobox family. | 0.414 |
ceh-60 | nob-1 | F22A3.5.1 | Y75B8A.2a.1 | Homeobox domain-containing protein. | Homeobox domain-containing protein. | 0.734 |
ceh-60 | psa-3 | F22A3.5.1 | F39D8.2a.1 | Homeobox domain-containing protein. | Meis_PKNOX_N domain-containing protein. | 0.645 |
ceh-60 | unc-62 | F22A3.5.1 | T28F12.2a.2 | Homeobox domain-containing protein. | Homeobox protein unc-62; Acts redundantly with ceh-20 and ceh-40 to perform overlapping roles during embryogenesis. Required for postembryonic development of the ectoderm, including the Q, V and P cell lineages, playing a crucial role in ensuring that these cells and their descendants undergo their invariant patterns of cell division, migration, fusion and morphogenesis. Has a role in the mig-13 pathway to promote anterior migration of neuroblasts in the Q lineage. Required for multiple roles in regulating vulva development. Belongs to the TALE/MEIS homeobox family. | 0.956 |
elt-1 | nhr-25 | W09C2.1a.1 | F11C1.6a.1 | Transcription factor elt-1; Transcriptional activator that binds to the consensus sequence 5'-[AT]GATA[AG]-3' and variations thereof. During embryonic development, required for specification of cell fate of major hypodermal (epidermal) cells at the blastomere stage. The requirement is true for all four lineages derived from ABarp, ABpra and C blastomeres. Required for seam cell maintenance in late embryogenesis, for proper formation of dauer larvae and locomotion. Regulates expression of bro-1, a regulator of seam cell proliferation, via a GATA-like binding motif. Probably represses ex [...] | Nuclear hormone receptor family member nhr-25; Orphan nuclear receptor required during development. Plays a role in male tail tip morphogenesis regulating the expression of the transcription factor dmd-3 in a negative feedback loop. | 0.808 |
elt-1 | nob-1 | W09C2.1a.1 | Y75B8A.2a.1 | Transcription factor elt-1; Transcriptional activator that binds to the consensus sequence 5'-[AT]GATA[AG]-3' and variations thereof. During embryonic development, required for specification of cell fate of major hypodermal (epidermal) cells at the blastomere stage. The requirement is true for all four lineages derived from ABarp, ABpra and C blastomeres. Required for seam cell maintenance in late embryogenesis, for proper formation of dauer larvae and locomotion. Regulates expression of bro-1, a regulator of seam cell proliferation, via a GATA-like binding motif. Probably represses ex [...] | Homeobox domain-containing protein. | 0.679 |
elt-1 | scrt-1 | W09C2.1a.1 | C55C2.1.1 | Transcription factor elt-1; Transcriptional activator that binds to the consensus sequence 5'-[AT]GATA[AG]-3' and variations thereof. During embryonic development, required for specification of cell fate of major hypodermal (epidermal) cells at the blastomere stage. The requirement is true for all four lineages derived from ABarp, ABpra and C blastomeres. Required for seam cell maintenance in late embryogenesis, for proper formation of dauer larvae and locomotion. Regulates expression of bro-1, a regulator of seam cell proliferation, via a GATA-like binding motif. Probably represses ex [...] | SCRaTch (Zinc finger transcriptional repressor) homolog. | 0.706 |
elt-1 | tbx-8 | W09C2.1a.1 | T07C4.2.1 | Transcription factor elt-1; Transcriptional activator that binds to the consensus sequence 5'-[AT]GATA[AG]-3' and variations thereof. During embryonic development, required for specification of cell fate of major hypodermal (epidermal) cells at the blastomere stage. The requirement is true for all four lineages derived from ABarp, ABpra and C blastomeres. Required for seam cell maintenance in late embryogenesis, for proper formation of dauer larvae and locomotion. Regulates expression of bro-1, a regulator of seam cell proliferation, via a GATA-like binding motif. Probably represses ex [...] | T-box transcription factor tbx-8; Involved in the control of early morphogenesis of the intestine, hypodermis and body-wall muscle. Appears to have partially redundant function to tbx-9. | 0.737 |
elt-1 | tbx-9 | W09C2.1a.1 | T07C4.6.1 | Transcription factor elt-1; Transcriptional activator that binds to the consensus sequence 5'-[AT]GATA[AG]-3' and variations thereof. During embryonic development, required for specification of cell fate of major hypodermal (epidermal) cells at the blastomere stage. The requirement is true for all four lineages derived from ABarp, ABpra and C blastomeres. Required for seam cell maintenance in late embryogenesis, for proper formation of dauer larvae and locomotion. Regulates expression of bro-1, a regulator of seam cell proliferation, via a GATA-like binding motif. Probably represses ex [...] | T-box transcription factor tbx-9; Involved in the control of early morphogenesis of the intestine, hypodermis and body-wall muscle. Appears to have partially redundant function to tbx-8. | 0.723 |
elt-1 | unc-62 | W09C2.1a.1 | T28F12.2a.2 | Transcription factor elt-1; Transcriptional activator that binds to the consensus sequence 5'-[AT]GATA[AG]-3' and variations thereof. During embryonic development, required for specification of cell fate of major hypodermal (epidermal) cells at the blastomere stage. The requirement is true for all four lineages derived from ABarp, ABpra and C blastomeres. Required for seam cell maintenance in late embryogenesis, for proper formation of dauer larvae and locomotion. Regulates expression of bro-1, a regulator of seam cell proliferation, via a GATA-like binding motif. Probably represses ex [...] | Homeobox protein unc-62; Acts redundantly with ceh-20 and ceh-40 to perform overlapping roles during embryogenesis. Required for postembryonic development of the ectoderm, including the Q, V and P cell lineages, playing a crucial role in ensuring that these cells and their descendants undergo their invariant patterns of cell division, migration, fusion and morphogenesis. Has a role in the mig-13 pathway to promote anterior migration of neuroblasts in the Q lineage. Required for multiple roles in regulating vulva development. Belongs to the TALE/MEIS homeobox family. | 0.444 |
nhr-25 | elt-1 | F11C1.6a.1 | W09C2.1a.1 | Nuclear hormone receptor family member nhr-25; Orphan nuclear receptor required during development. Plays a role in male tail tip morphogenesis regulating the expression of the transcription factor dmd-3 in a negative feedback loop. | Transcription factor elt-1; Transcriptional activator that binds to the consensus sequence 5'-[AT]GATA[AG]-3' and variations thereof. During embryonic development, required for specification of cell fate of major hypodermal (epidermal) cells at the blastomere stage. The requirement is true for all four lineages derived from ABarp, ABpra and C blastomeres. Required for seam cell maintenance in late embryogenesis, for proper formation of dauer larvae and locomotion. Regulates expression of bro-1, a regulator of seam cell proliferation, via a GATA-like binding motif. Probably represses ex [...] | 0.808 |
nhr-25 | nob-1 | F11C1.6a.1 | Y75B8A.2a.1 | Nuclear hormone receptor family member nhr-25; Orphan nuclear receptor required during development. Plays a role in male tail tip morphogenesis regulating the expression of the transcription factor dmd-3 in a negative feedback loop. | Homeobox domain-containing protein. | 0.793 |