node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
F46C5.6 | Y71H2AM.20 | F46C5.6.1 | Y71H2AM.20a.1 | Uncharacterized protein. | Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. | 0.958 |
F46C5.6 | ZK688.9 | F46C5.6.1 | ZK688.9.1 | Uncharacterized protein. | TIP41-like protein; Belongs to the TIP41 family. | 0.884 |
F46C5.6 | paa-1 | F46C5.6.1 | F48E8.5.2 | Uncharacterized protein. | Probable serine/threonine-protein phosphatase PP2A regulatory subunit; Acts as a scaffolding protein for phosphatase let-92 and its regulatory subunits (Probable). Probably together with let-92 and regulatory subunit sur-6, regulates centriole duplication, microtubule outgrowth and mitotic spindle stability during early embryonic cell division by preventing the degradation of sas-5 and kinase zyg-1. During vulva development, may play a role with phosphatase let-92 and regulatory subunit sur-6 in the induction of vulva cell precursors by positively regulating let-60/Ras- MAP kinase sign [...] | 0.626 |
F46C5.6 | ppfr-1 | F46C5.6.1 | F16A11.3d.1 | Uncharacterized protein. | Serine/threonine-protein phosphatase 4 regulatory subunit 1; Probable regulatory subunit of serine/threonine-protein phosphatase PP4 which may play a role in meiosis and embryonic mitosis. Probably in association with catalytic subunit pph-4.1, regulates microtubule severing during oocyte meiosis II by dephosphorylating and likely activating mei-1, a component of the katanin microtubule severing complex. | 0.774 |
F46C5.6 | ppfr-2 | F46C5.6.1 | D2092.2.1 | Uncharacterized protein. | Protein Phosphatase Four Regulatory subunit. | 0.858 |
F46C5.6 | ppfr-4 | F46C5.6.1 | Y71H2B.3.1 | Uncharacterized protein. | Serine/threonine-protein phosphatase 4 regulatory subunit ppfr-4; Probable regulatory subunit of serine/threonine-protein phosphatase PP4 which may play a role in meiosis and embryonic mitosis. Probably in association with catalytic subunit pph-4.1, regulates microtubule severing during oocyte meiosis II by dephosphorylating and likely activating mei-1, a component of the katanin microtubule severing complex. | 0.890 |
F46C5.6 | pph-4.1 | F46C5.6.1 | Y75B8A.30.1 | Uncharacterized protein. | Serine/threonine-protein phosphatase 4 catalytic subunit 1; Protein phosphatase which plays an essential role in meiosis and in early embryonic mitosis. During spermatocyte meiosis and the first embryonic mitosis, regulates centrosome maturation, and thus spindle formation, by recruiting some of the components of the pericentriolar material (PCM). During oocyte meiosis I, regulates meiotic chromosome dynamics including synapsis-independent chromosome pairing, restriction of synapsis to homologous chromosomes, programmed DNA double-strand break initiation and crossover formation resulti [...] | 0.888 |
F46C5.6 | smk-1 | F46C5.6.1 | F41E6.4a.1 | Uncharacterized protein. | SMK-1 domain-containing protein. | 0.494 |
F46C5.6 | sur-6 | F46C5.6.1 | F26E4.1.1 | Uncharacterized protein. | Serine/threonine-protein phosphatase 2A regulatory subunit sur-6; Probable regulatory subunit of serine/threonine phosphatase let-92. Together with let-92 and constant regulatory subunit paa-1, positively regulates centriole duplication during early embryonic cell divisions by preventing the degradation of sas-5 and kinase zyg-1. In addition, during vulva development, may play a role with phosphatase let-92 and regulatory subunit paa-1 in the induction of vulva cell precursors by positively regulating let-60/Ras- MAP kinase signaling, probably by promoting lin-45 activation. In intesti [...] | 0.937 |
Y71H2AM.20 | F46C5.6 | Y71H2AM.20a.1 | F46C5.6.1 | Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. | Uncharacterized protein. | 0.958 |
Y71H2AM.20 | ZK688.9 | Y71H2AM.20a.1 | ZK688.9.1 | Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. | TIP41-like protein; Belongs to the TIP41 family. | 0.907 |
Y71H2AM.20 | paa-1 | Y71H2AM.20a.1 | F48E8.5.2 | Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. | Probable serine/threonine-protein phosphatase PP2A regulatory subunit; Acts as a scaffolding protein for phosphatase let-92 and its regulatory subunits (Probable). Probably together with let-92 and regulatory subunit sur-6, regulates centriole duplication, microtubule outgrowth and mitotic spindle stability during early embryonic cell division by preventing the degradation of sas-5 and kinase zyg-1. During vulva development, may play a role with phosphatase let-92 and regulatory subunit sur-6 in the induction of vulva cell precursors by positively regulating let-60/Ras- MAP kinase sign [...] | 0.983 |
Y71H2AM.20 | ppfr-1 | Y71H2AM.20a.1 | F16A11.3d.1 | Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. | Serine/threonine-protein phosphatase 4 regulatory subunit 1; Probable regulatory subunit of serine/threonine-protein phosphatase PP4 which may play a role in meiosis and embryonic mitosis. Probably in association with catalytic subunit pph-4.1, regulates microtubule severing during oocyte meiosis II by dephosphorylating and likely activating mei-1, a component of the katanin microtubule severing complex. | 0.830 |
Y71H2AM.20 | ppfr-2 | Y71H2AM.20a.1 | D2092.2.1 | Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. | Protein Phosphatase Four Regulatory subunit. | 0.984 |
Y71H2AM.20 | ppfr-4 | Y71H2AM.20a.1 | Y71H2B.3.1 | Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. | Serine/threonine-protein phosphatase 4 regulatory subunit ppfr-4; Probable regulatory subunit of serine/threonine-protein phosphatase PP4 which may play a role in meiosis and embryonic mitosis. Probably in association with catalytic subunit pph-4.1, regulates microtubule severing during oocyte meiosis II by dephosphorylating and likely activating mei-1, a component of the katanin microtubule severing complex. | 0.946 |
Y71H2AM.20 | pph-4.1 | Y71H2AM.20a.1 | Y75B8A.30.1 | Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. | Serine/threonine-protein phosphatase 4 catalytic subunit 1; Protein phosphatase which plays an essential role in meiosis and in early embryonic mitosis. During spermatocyte meiosis and the first embryonic mitosis, regulates centrosome maturation, and thus spindle formation, by recruiting some of the components of the pericentriolar material (PCM). During oocyte meiosis I, regulates meiotic chromosome dynamics including synapsis-independent chromosome pairing, restriction of synapsis to homologous chromosomes, programmed DNA double-strand break initiation and crossover formation resulti [...] | 0.915 |
Y71H2AM.20 | smk-1 | Y71H2AM.20a.1 | F41E6.4a.1 | Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. | SMK-1 domain-containing protein. | 0.960 |
Y71H2AM.20 | sur-6 | Y71H2AM.20a.1 | F26E4.1.1 | Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. | Serine/threonine-protein phosphatase 2A regulatory subunit sur-6; Probable regulatory subunit of serine/threonine phosphatase let-92. Together with let-92 and constant regulatory subunit paa-1, positively regulates centriole duplication during early embryonic cell divisions by preventing the degradation of sas-5 and kinase zyg-1. In addition, during vulva development, may play a role with phosphatase let-92 and regulatory subunit paa-1 in the induction of vulva cell precursors by positively regulating let-60/Ras- MAP kinase signaling, probably by promoting lin-45 activation. In intesti [...] | 0.824 |
ZK688.9 | F46C5.6 | ZK688.9.1 | F46C5.6.1 | TIP41-like protein; Belongs to the TIP41 family. | Uncharacterized protein. | 0.884 |
ZK688.9 | Y71H2AM.20 | ZK688.9.1 | Y71H2AM.20a.1 | TIP41-like protein; Belongs to the TIP41 family. | Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. | 0.907 |