STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
vps-28Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex, a regulator of vesicular trafficking process; Belongs to the VPS28 family. (210 aa)    
Predicted Functional Partners:
mvb-12
MVB (Yeast MultiVesicular Body sorting factor) related.
   
 0.999
tsg-101
Tumor Susceptibility Gene homolog.
   
 0.999
vps-37
VPS37 C-terminal domain-containing protein.
   
 0.999
vps-36
GLUE N-terminal domain-containing protein.
   
 0.998
vps-25
Related to yeast Vacuolar Protein Sorting factor.
   
 0.998
vps-20
Related to yeast Vacuolar Protein Sorting factor.
   
 0.992
vps-24
Related to yeast Vacuolar Protein Sorting factor.
   
 0.987
hgrs-1
Hepatocyte Growth factor-Regulated TK Substrate (HRS) family.
    
 0.979
vps-2
Related to yeast Vacuolar Protein Sorting factor.
   
 0.975
vps-60
Related to yeast Vacuolar Protein Sorting factor.
   
  
 0.973
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.