STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZC506.1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (931 aa)    
Predicted Functional Partners:
F10C2.5
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
  
0.946
C47E12.3
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
  
 
0.938
E01G4.5
Uncharacterized protein.
      
 0.700
cysl-1
Cysteine synthase 1; Catalyzes the formation of cysteine and acetate from O- acetylserine and hydrogen sulfide. By metabolizing hydrogen sulfide produced by cysl-2-mediated cyanide assimilation, mediates resistance to P.aeruginosa infection. Mediates survival in high levels of hydrogen sulfide. By sequestering egl-9, which in turn promotes hif-1- mediated transcription, regulates behavioral responses to hypoxia ; Belongs to the cysteine synthase/cystathionine beta- synthase family.
   
  
 0.666
sel-1
Suppressor/Enhancer of Lin-12.
   
 
 0.597
C03H12.1
Uncharacterized protein.
   
 
 0.580
ribo-1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]
   
 
 0.488
uggt-1
UDP-Glucose Glycoprotein glucosylTransferase.
   
  
 0.479
aman-2
Alpha-mann_mid domain-containing protein.
   
 
 0.461
uggt-2
UDP-Glucose Glycoprotein glucosylTransferase.
   
  
 0.457
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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