STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mtx-2Metaxin-2 homolog. (260 aa)    
Predicted Functional Partners:
gop-3
SAM50-like protein gop-3; May play a role in the maintenance of the structure of mitochondrial cristae; Belongs to the SAM50/omp85 family.
   
 0.975
mtx-1
Metaxin-1 homolog; Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity); Belongs to the metaxin family.
  
 
0.921
trak-1
HAP1 N-terminal domain-containing protein.
    
 
 0.841
tomm-7
Mitochondrial import receptor subunit TOM7 homolog; Belongs to the Tom7 family.
     
 0.830
chch-3
MICOS complex subunit MIC19; Plays a role in maintaining mitochondrial morphology. May act as a component of the MICOS complex, a large protein complex of the mitochondria (By similarity). Belongs to the MICOS complex subunit Mic19 family. Metazoan Mic19 subfamily.
   
 
 0.828
ZK686.2
Putative ATP-dependent RNA helicase ZK686.2; Probable ATP-binding RNA helicase; Belongs to the DEAD box helicase family.
 
 
    0.808
tomm-20
Mitochondrial import receptor subunit TOM20 homolog; Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins (By similarity). Together with tomm-22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the translocation pore.
   
 
 0.747
immt-1
MICOS complex subunit MIC60-1; Sustains mitochondrial morphology probably through maintaining cristae morphology. May act as a component of the MICOS complex, a large protein complex of the mitochondria (By similarity).
    
 
 0.728
rpc-25
RNA Polymerase, Class III (C).
   
  
 0.707
tomm-40
Mitochondrial import receptor subunit TOM40 homolog; Channel-forming protein essential for import of protein precursors into mitochondria. Specifically required for nnt-1 accumulation in the mitochondria and may be involved in the secretion of daf-28/insulin from the mitochondria. Required for embryonic and larval development.
   
 
 0.700
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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