STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZK1127.5Probable RNA 3'-terminal phosphate cyclase-like protein; Does not have cyclase activity. Plays a role in 40S- ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA (By similarity); Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily. (379 aa)    
Predicted Functional Partners:
Y61A9LA.10
Bms1-type G domain-containing protein.
   
 0.999
byn-1
Uncharacterized protein byn-1; Belongs to the bystin family.
   
 
 0.998
utp-20
DRIM domain-containing protein.
   
 
 0.996
F55F8.3
Periodic tryptophan protein 2 homolog; Belongs to the WD repeat PWP2 family.
   
 
 0.996
T02H6.1
WD_REPEATS_REGION domain-containing protein.
   
 
 0.996
nol-14
NucleOLar protein.
   
 
 0.996
ZK795.3
Brix domain-containing protein ZK795.3.
   
 
 0.996
Y73E7A.2
Uncharacterized protein.
   
 
 0.995
toe-1
HEAT repeat-containing protein 1 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity); Belongs to the HEATR1/UTP10 family.
   
 
 0.995
B0280.9
U3 small nucleolar RNA-associated protein 18 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the WD repeat UTP18 family.
   
 
 0.993
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.