STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
wrt-6Warthog protein 6 C-product; Intercellular signal essential for a variety of patterning events during development; Belongs to the hedgehog family. (593 aa)    
Predicted Functional Partners:
wrt-10
WaRThog (Hedgehog-like family).
 
 
  
 0.843
col-79
Putative cuticle collagen 79; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment (By similarity).
   
  
 0.772
R08E5.1
Methyltranfer_dom domain-containing protein.
   
 
 0.703
wrt-4
Warthog protein 4 C-product; Intercellular signal essential for a variety of patterning events during development.
   
  
0.698
F47C12.7
Uncharacterized protein.
      
 0.696
E02H1.6
Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. AMP and dAMP are the preferred substrates, but CMP and TMP are also good substrates. ATP and dATP are the best phosphate donors. May have a role in nuclear energy homeostasis; Belongs to the adenylate kinase family. AK6 subfamily.
      
 0.695
grl-5
Ground-like domain-containing protein.
   
  
 0.677
grd-2
GRounDhog (Hedgehog-like family).
   
  
0.631
fig-1
Uncharacterized protein.
   
  
 0.625
che-14
SSD domain-containing protein.
   
 
 0.621
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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