STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lars-2Anticodon_1 domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (859 aa)    
Predicted Functional Partners:
ears-2
tRNA-synt_1c domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.983
qars-1
Probable glutamine--tRNA ligase.
  
 
 0.974
pars-2
AA_TRNA_LIGASE_II domain-containing protein.
  
 
 0.972
rars-2
DALR_1 domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.968
prx-10
Tryptophan--tRNA ligase, mitochondrial; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.968
nars-2
AA_TRNA_LIGASE_II domain-containing protein.
  
 
 0.967
fars-2
Mitochondrial phenylalanyl-tRNA synthetase.
  
  
 0.966
yars-2
Tyrosine--tRNA ligase.
  
 
 0.960
aars-2
Alanine--tRNA ligase, cytoplasmic; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family.
  
 
 0.957
eral-1
Uncharacterized GTP-binding protein E02H1.2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
  
  
 0.941
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.