node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
F52C6.3 | Y37B11A.2 | F52C6.3.1 | Y37B11A.2a.1 | Ubiquitin-like domain-containing protein. | DNA polymerase. | 0.516 |
F52C6.3 | pcn-1 | F52C6.3.1 | W03D2.4.1 | Ubiquitin-like domain-containing protein. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.821 |
F52C6.3 | polh-1 | F52C6.3.1 | F53A3.2.1 | Ubiquitin-like domain-containing protein. | UmuC domain-containing protein. | 0.765 |
F52C6.3 | polk-1 | F52C6.3.1 | F22B7.6a.1 | Ubiquitin-like domain-containing protein. | DNA polymerase kappa; DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Depending on the context, it inserts the correct base, but causes frequent base transitions, transversions and frameshifts. Lacks 3'-5' proofreading exonuclease activity. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity (By similarity). Belongs to the DNA polymerase type-Y family. | 0.618 |
F52C6.3 | rev-1 | F52C6.3.1 | ZK675.2.1 | Ubiquitin-like domain-containing protein. | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. | 0.823 |
F52C6.3 | ubq-1 | F52C6.3.1 | F25B5.4a.2 | Ubiquitin-like domain-containing protein. | Ubiquitin-related; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involved in protein degrad [...] | 0.486 |
F52C6.3 | ubq-2 | F52C6.3.1 | ZK1010.1.1 | Ubiquitin-like domain-containing protein. | Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is invol [...] | 0.920 |
F52C6.3 | uev-1 | F52C6.3.1 | F39B2.2.1 | Ubiquitin-like domain-containing protein. | Ubiquitin-conjugating enzyme E2 variant 1; Involved in protein ubiquitination, but has no ubiquitin ligase activity on its own. The uev-1-ubc-13 heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through Lys-63. Involved in sorting Lys-63-linked polyubiquitinated maternal membrane proteins for degradation by targeting to multivesicular bodies. Required for glr-1-containing glutamate receptor trafficking in neurons. May have a role in synaptic transmission at motorneurons. May be involved in the ubiquitination and growth of intracellular polygluta [...] | 0.918 |
Y37B11A.2 | F52C6.3 | Y37B11A.2a.1 | F52C6.3.1 | DNA polymerase. | Ubiquitin-like domain-containing protein. | 0.516 |
Y37B11A.2 | pcn-1 | Y37B11A.2a.1 | W03D2.4.1 | DNA polymerase. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.962 |
Y37B11A.2 | polh-1 | Y37B11A.2a.1 | F53A3.2.1 | DNA polymerase. | UmuC domain-containing protein. | 0.990 |
Y37B11A.2 | polk-1 | Y37B11A.2a.1 | F22B7.6a.1 | DNA polymerase. | DNA polymerase kappa; DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Depending on the context, it inserts the correct base, but causes frequent base transitions, transversions and frameshifts. Lacks 3'-5' proofreading exonuclease activity. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity (By similarity). Belongs to the DNA polymerase type-Y family. | 0.980 |
Y37B11A.2 | rad-51 | Y37B11A.2a.1 | Y43C5A.6a.1 | DNA polymerase. | DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. | 0.922 |
Y37B11A.2 | rev-1 | Y37B11A.2a.1 | ZK675.2.1 | DNA polymerase. | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. | 0.998 |
Y37B11A.2 | ubq-1 | Y37B11A.2a.1 | F25B5.4a.2 | DNA polymerase. | Ubiquitin-related; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involved in protein degrad [...] | 0.510 |
Y37B11A.2 | ubq-2 | Y37B11A.2a.1 | ZK1010.1.1 | DNA polymerase. | Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is invol [...] | 0.520 |
Y37B11A.2 | uev-1 | Y37B11A.2a.1 | F39B2.2.1 | DNA polymerase. | Ubiquitin-conjugating enzyme E2 variant 1; Involved in protein ubiquitination, but has no ubiquitin ligase activity on its own. The uev-1-ubc-13 heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through Lys-63. Involved in sorting Lys-63-linked polyubiquitinated maternal membrane proteins for degradation by targeting to multivesicular bodies. Required for glr-1-containing glutamate receptor trafficking in neurons. May have a role in synaptic transmission at motorneurons. May be involved in the ubiquitination and growth of intracellular polygluta [...] | 0.885 |
Y37B11A.2 | ung-1 | Y37B11A.2a.1 | Y56A3A.29a.1 | DNA polymerase. | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.711 |
pcn-1 | F52C6.3 | W03D2.4.1 | F52C6.3.1 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Ubiquitin-like domain-containing protein. | 0.821 |
pcn-1 | Y37B11A.2 | W03D2.4.1 | Y37B11A.2a.1 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | DNA polymerase. | 0.962 |